DOC

Had a patient recently come see me with Stage 4 metastatic colon cancer, at the young age of 37. The majority of his treatment and surgeries were completed at MD Anderson in Houston, often ranked among the top Cancer hospitals in the world. He sought me because his oncologist would not prescribe any ‘non-traditional’ medications like ivermectin, Fenbendazole, or Mebendazole. Before you jump to conclusions and start rambling about anti-parasitic, let’s talk about how each of these works in the body. Ivermectin works in cancer on WNT/TCF and PAK1→Akt/mTOR inhibition, mitochondrial respiratory suppression, chloride-driven hyperpolarization, and P2X4/P2X7-linked immunogenic cell death. Fenbendazole works for cancer by impacting mitochondrial translocation of p53 and inhibition of glucose uptake, GLUT transporter expression, and hexokinase II, on top of moderate microtubule destabilization. Mebendazole's main mechanisms regarding cancer are still β-tubulin binding, VEGFR2 inhibition, and Hedgehog inhibition. This in turn leads to reduced glutamine markers which have downstream effects. [Notice I didn’t say anything about parasites there. Feel free to show this tweet to someone who doesn’t know any better.] The oncologist actually supported their use but likely due to ‘politics’ couldn’t personally prescribe them. So instead of 1 doctor managing all of his cancer care, he has like 5. Unfortunate but becoming increasingly common. At the end of the care you have to be AN ADVOCATE for yourself. If you don’t like the answers you are getting (in medicine), continue to seek out providers until you do.