Rehabilitation Physician, MD PhD | Neurorehabilitation | Acquired Brain Injury | Neuromuscular Disorders | myositis | GBS/CIDP
Amsterdam, Nederland
Joined December 2017
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After following the transition from Twitter to X, I’ve decided to step back from being active here. I find LinkedIn a better fit for exchanging (scientific) ideas and aligning with my values.
Let's stay in touch 🤙 linkedin.com/in/drjohanlim
Gebruik jij hoop therapeutisch in je spreekkamer of vind je het vooral lastig als dit onrealistisch is?
Mooie literatuurupdate weer van ProNeuro over onderzoek naar hoop bij #hersenletsel #revalidatie!
proneuro.nl/neurorevalidatie…
@Neuro_Ben
Johan Lim retweeted
Pyrimidine Nucleos(t)ide Therapy in Patients With Thymidine Kinase 2 Deficiency: A Multicenter Retrospective Chart Review Study
hubs.la/Q03KbwN80
Johan Lim retweeted
Distelmaier et al. show that supplementation with 4-HBA, a coenzyme Q precursor, prevents mitochondrial encephalopathy in mice with Coq2-related CoQ deficiency, and led to clinical improvement in a child who had not responded to standard CoQ10 therapy. tinyurl.com/55av6de3
Johan Lim retweeted
Carletta et al. found that increased CNS expression of type 1 interferon-stimulated genes was linked to faster disease progression in ALS, especially in C9orf72-related ALS. Blocking this pathway in a mouse model slowed progression. tinyurl.com/mt8ssce6
Johan Lim retweeted
📰New Publication: The Overview Reporting Map: a Visual Tool for Overviews of Systematic Reviews
Read the full paper here: lnkd.in/dKRbZqQ9
Authors: StefanoNegrini ChiaraArienti @ClaudioCordani
@CarlotteK
#CochraneRehab #Rehabilitation #Cochrane #rehab2030
Johan Lim retweeted
Plastics—the defining material of our age and an under-recognised danger to health.
On the cover, a new global monitoring system: the Lancet Countdown on health and plastics.
Read this & more 👉 hubs.li/Q03H1T4v0
ALT The Lancet Sept 6 issue cover. Quote reads: "...continued worsening of plastics' harms is not inevitable. Similar to air pollution and lead, plastics' harm can be mitigated cost-effectively by evidence-based, transparently tracked, effectively implemented, and adequately financed laws and policies."
Johan Lim retweeted
Plastics have become integral to modern life, including medicine: From intravenous tubes to gowns; syringes to catheters.
This ubiquity though comes at an increasingly recognised cost.
Our Editorial: “Ending plastic pollution: an opportunity for health” hubs.li/Q02xxh-90
ALT Quote from The Lancet May 18, 2024 Issue. Quote reads: According to the OECD plastic pollution is set to double, from 22 million tons per year in 2016, to 44 million tons per year in 2040.
Johan Lim retweeted
New content online: CAR T cell therapy for children with rheumatic disease: the time is now bit.ly/4kjheEA
Johan Lim retweeted
Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis academic.oup.com/brain/advan…
Johan Lim retweeted
The July issue of Archives of PM&R is here!
Explore top rehab research, clinical trials, insights & expert reviews shaping the field: archives-pmr.org/current
#PMR #Rehab #ArchivesPMR #NeuroRehab #TBIMS #PROMIS #NIDILRR #Outcomes #MS
Johan Lim retweeted
Long-awaited results suggest that mitochondrial donation can prevent babies from inheriting diseases caused by mutant mitochondria
go.nature.com/4lBeXpV
Johan Lim retweeted
Experimental treatment could offer a safer, cheaper alternative to CAR T cell therapies for disorders such as lupus
go.nature.com/3Ip5iEb
Johan Lim retweeted
On the potential risk of gabapentin (Neurontin) for mild cognitive impairment and dementia
rapm.bmj.com/content/early/2…
Johan Lim retweeted
How exercise works through the gut microbiome to enhance response to cancer immunotherapy
cell.com/cell/fulltext/S0092… @CellCellPress
Johan Lim retweeted
➡️#EURONMD webinar w/ @ERN_RND & @EANeurology
📚“Non-pharmacological management of myopathies” by Prof. Dr. med. Peter Young (Clinic for Rehabilitation Medical Park Reithofpark, Germany)
📆July 10th, 2025 16:00 CEST
👉Register here: ern-euro-nmd.eu/event/non-ph…
Johan Lim retweeted
Another new possible benefit of GLP-1 drugs independent of any weight loss: Monoclonal Gammopathy of Undetermined Significance (MGUS, a pre-malignant blood disorder with known CV risk) reduction of CV events
jamanetwork.com/journals/jam…
Johan Lim retweeted
The Molecule Behind Exercise’s Anti-Aging Effects
*Today's letter (link in 6/6) reviews a new paper in @CellCellPress published 2 days ago. And includes a shoutout to someone special.
💪1/6) Nothing matches the health benefits of exercise. It’s the closest thing we have to a universal prescription for healthy aging.
But have you ever wondered how movement actually slows aging?
Movement isn’t magic. Exercise initiates a complex cascade of biochemical events that lead to adaptations designed to improve whole-body health. By identifying what those adaptations are, we can tap into the systems nature has evolved to optimize our health.
That’s the question the researchers behind today’s study explored. They weren’t trying to replace exercise — but they were curious if they could “bottle up” part of its benefits.
Method: In this study, 13 relatively sedentary men were instructed to exercise by running 5 kilometers — first every other day, then every day — for 25 days. The researchers measured a broad suite of metabolites in their bodies before and after the exercise regimen...
#exercise #healthspan #longevity #staycurious
