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galante_lab

@GalanteLab

Pedro Galante's Lab: Gene expression regulation, mobile elements, cancer targets, and bioinformatics tools.

 Sao Paulo, Brazil
bioinfo.mochsl.org.br/
Joined June 2020
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Super happy to share that our paper is finally published in Aging Cell! 🥳 Read the full manuscript here: onlinelibrary.wiley.com/doi/… Our study investigated transcriptomic entropy using RNA-sequencing data from thousands of samples across human and mouse tissues.
Tissue‐Level Transcriptomic Entropy Reveals Organ‐Specific Aging Patterns and Predicts Cancer...

Tissue‐Level Transcriptomic Entropy Reveals Organ‐Specific Aging Patterns and Predicts Cancer...

Tissue-level transcriptomic entropy shows organ-specific trajectories during aging and is elevated in cancers. Across large human cohorts, higher entropy associates with proliferation, senescence,...

onlinelibrary.wiley.com
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Pesquisa desvenda como alguns tipos de #câncerdemama ‘driblam’ tratamento. Descoberta aumentou de 13 para 90 o número de variações conhecidas da proteína HER2, alvo de medicamentos avançados contra a doença; diversidade pode explicar resistência a terapias agencia.fapesp.br/56396
Image from Agência FAPESP (@AgenciaFAPESP)
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AI video about our latest preprint. I wasn't familiar with the "podcast," but the video is surprisingly accurate — almost a bit scary lol. youtube.com/watch?v=3PS7Fnx4… Read the full story here (we're adding some analyses before submission — stay tuned!): biorxiv.org/content/10.1101/…
Transcriptomic Entropy: A Molecular Signature of Aging and Cancer

Transcriptomic Entropy: A Molecular Signature of Aging and Cancer

The link to the original preprint: https://www.biorxiv.org/content...

youtube.com
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NEW PREPRINT ALERT:Transcriptomic entropy reveals tissue-specific patterns in aging and predicts cancer progression 🧵👇 biorxiv.org/content/10.1101/…
Transcriptomic entropy reveals tissue-specific patterns in aging and predicts cancer progression

Transcriptomic entropy reveals tissue-specific patterns in aging and predicts cancer progression

Aging and cancer share complex molecular mechanisms, yet distinguishing between causative factors and byproducts remains challenging. Here, we investigated the role of transcriptomic entropy in aging...

biorxiv.org
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Paper 2/2 of our pilot prediction model to determine survival probability on #immunotherapy I would like to highlight the potential importance of the HLA-A point mutations in a neoantigen-restricted scenario (TMB-low cohort) @MDAndersonNews @pmcancercentre doi.org/10.1093/oncolo/oyaf0…
Image from Camila Braganca Xavier (@CamilaBragancaX)
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The latest edition of @JPathology is now available online (Vol 256 Issue 2). onlinelibrary.wiley.com/toc/… Editor's choice & Cover Image article (free to read)- onlinelibrary.wiley.com/doi/… #PATHSOC #journalofpathology #JPATH #pathology
The Journal of Pathology- February 2022- Vol 256 Issue 2

ALT The Journal of Pathology- February 2022- Vol 256 Issue 2

Rodrigo Araujo Sequeira Barreiro, Jorge Sabbaga, Benedito M Rossi, Maria Isabel W Achatz, Fabiana Bettoni, Anamaria A Camargo, Paula F Asprino1* andPedro A F Galante* Monoallelic deleteriousMUTYHgermline variants asa driver for tumorigenesis J Pathol February 2022; 256: 214–222. https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5829

ALT Rodrigo Araujo Sequeira Barreiro, Jorge Sabbaga, Benedito M Rossi, Maria Isabel W Achatz, Fabiana Bettoni, Anamaria A Camargo, Paula F Asprino1* andPedro A F Galante* Monoallelic deleteriousMUTYHgermline variants asa driver for tumorigenesis J Pathol February 2022; 256: 214–222. https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5829

Rodrigo Araujo Sequeira Barreiro, Jorge Sabbaga, Benedito M Rossi, Maria Isabel W Achatz, Fabiana Bettoni, Anamaria A Camargo, Paula F Asprino1* andPedro A F Galante* Monoallelic deleteriousMUTYHgermline variants asa driver for tumorigenesis J Pathol February 2022; 256: 214–222. https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5829

ALT Rodrigo Araujo Sequeira Barreiro, Jorge Sabbaga, Benedito M Rossi, Maria Isabel W Achatz, Fabiana Bettoni, Anamaria A Camargo, Paula F Asprino1* andPedro A F Galante* Monoallelic deleteriousMUTYHgermline variants asa driver for tumorigenesis J Pathol February 2022; 256: 214–222. https://onlinelibrary.wiley.com/doi/epdf/10.1002/path.5829

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