Hannah Stuart (@H_T_Stuart) profile picture

Sir Henry @wellcometrust postdoc fellow with @Tanaxolotl & @briscoejames labs | @ImpVienna & @TheCrick | PhD @SCICambridge | never too many cacti or hamsters |

Joined January 2012
Hannah Stuart retweeted
So happy to finally share for the first time how to obtain neural organoids from human naïve pluripotent stem cells! Thanks to the huge effort of @CeciliaLaterza_ @cesare_elisa @H_T_Stuart and all the contributors 🥳
From naïve pluripotency to human neural organoids through a three-dimensional morphogenetic continuum biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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From naïve pluripotency to human neural organoids through a three-dimensional morphogenetic continuum biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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I am beyond excited and happy to share that our work is finally out in @Dev_Cell as of today🥹🥳 “Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition” sciencedirect.com/science/ar…
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I am very excited to share our latest manuscript on the axolotl nervous system. We established the use of adeno-associated viruses (AAVs) to perform circuit tracing in the axolotl brain and retina: doi.org/10.1101/2024.02.15.5… with @Tanaxolotl @IMPVienna
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It is out 🧧! Huanhuan Li et al report on the generation of mouse cells with molecular and functional properties of embryo morula cells. @JiekaiChen @guomingyue_tj @zhangman1019 @MMingwei @H_T_Stuart @LawrenceEBates @olidailyflash @jywu_wu cell.com/developmental-cell/…
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📢 It is with joy and humbleness that I share our first contribution to Huntington Disease(HD) research, out in @NatureComms. We identified genes with therapeutic potential against HD using pluripotent cells. 1/11 shorturl.at/dvEH8 #HuntingtonsDisease #stemcells
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Have you ever wondered who organizes the organizer? Excited to share our latest discoveries about how a global application of retinoic acid (RA) can induce polarized neural tube organoids (NTOs). For more details, check out our pre-print below: biorxiv.org/content/10.1101/… 1/6
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Hannah Stuart retweeted
I find so eternally alluring this developmental biology question of ‘who organises the organisers?’. Check out this beautiful and relevant new preprint of work spearheaded by @teresakatharin1, @Hstuart21, Elena Gromberg and others. Congratulations! biorxiv.org/content/10.1101/…
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New from Teresa Krammer, @Hstuart21 & co Organisers organise in organoids. But how? BMP signaling & physical sorting is responsible for self-organisation of FoxA2 expressing floorplate in neural tube organoids derived clonally from ES cells in vitro biorxiv.org/content/10.1101/…
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Hannah Stuart retweeted
Amazing science, people and location. Thanks @ScienceCluster for the opportunity to share our recent work
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3D ECM-rich environment sustains the identity of naive human iPSCs dlvr.it/SdhzXp
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Hannah Stuart retweeted
We are really excited our work is finally out @CellStemCell! Have a read if you want to know more about the supportive role of ECM on human naive pluripotency. Congrats to @cesare_elisa @UrciuoloLab @Hstuart21 for the amazing work 👏
3D ECM-rich environment sustains the identity of naive human iPSCs dlvr.it/SdhzXp
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I am full of joy to see our paper exploring the axolotl telencephalon published in @ScienceMagazine today. What an honor to work together with such a dream team: @AshleyMaynard10, @tomsgoms, @josch_f, @GrayCampLab, @Tanaxolotl and @TreutleinLab!!!
So exciting to explore the #axolotl brain, its regeneration and evolutionary conservation through single cell omics! Outstanding collaboration with @Tanaxolotl @IMPvienna lead by talents @LustKatharina, @AshleyMaynard10, @tomsgoms! @ScienceMagazine @ETH_en science.org/doi/10.1126/scie…
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So pleased to see our latest work published! This investigates how cellular identity change is instructed using reprogramming as a model system. Distinct Molecular Trajectories Converge to Induce Naive Pluripotency cell.com/cell-stem-cell/full…
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Stat3 induction reprograms through an early ICM state cell.com/cell-stem-cell/full… - nice demonstration that LIF/Stat3 signalling could be more about ICM identity than just epiblast.
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