Jack Hall (@Hall8Jack) profile picture

Biotech, Commodities, etc. A like is not necessarily a like.

United States
Joined July 2014
Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)Photo by Jack Hall (@Hall8Jack)
“That’s complete BS,” said Jeff Leiden, executive chairman of Vertex Pharmaceuticals , recalling a recent conversation with a tech leader who claimed AI would cure 90% of human disease in the next seven years. Vertex has used roughly 50 AI companies to comb through its data set of 10,000 drug compounds, Leiden said. Not one managed to generate a working drug. wsj.com/tech/ai/silicon-vall…
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For the 95% of rare disease patients still without an approved treatment, FDA is working for you. Acting Commissioner Kyle Diamantas shares how FDA is transforming rare disease drug development through the new Rare Disease Framework Initiative. Because every family deserves answers, action, and hope. fda.gov/news-events/fda-voic…
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It is so fucking hard to want to like either party. They are both so full of shit. I love this country so much. But I absolutely cannot stand our politicians.
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$SRPT Sarepta Therapeutics Q3 earnings — Revenue $381.40M vs $350.10M est, down 5.00% YoY — EPS $0.13 vs $0.36 est, a big miss — 2026 net product revenue guide $1.25B-$1.3B, low end raised by $50M Not financial advice.
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$ALNY Alnylam Announces $1 Billion Share Repurchase Program and Change in Commercial Leadership - Alnylam expects approximately $500 million of repurchases by year-end 2026, with the balance during 2027, subject to market conditions. stocktitan.net/news/ALNY/aln…
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BREAKING: Secretary of State Marco Rubio now expected to resign and launch a presidential bid, as he "needs to distance himself from the Iran war and pin that one on Trump," per The Independent. He will "run for the hills in the aftermath of the midterms humiliation," one Rubio ally said. "Rubio will be gone after the midterms. There will be about four or five of them running for the hills," the Rubio ally adds. A Republican source close to Rubio said "The country has completely turned against Trump. People cannot even say where Iran is on a map and do not get this war. The cost of gas has really pissed people off."
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BREAKING: The Volatility Index, $VIX, surges over +70% on the day, on track for its biggest daily gain since February 2018. Not even March 2020 saw a daily jump in volatility like we are seeing now.
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When we return next week, we’ll get 218 signatures for Epstein Files Transparency Act II, which guarantees a vote. Survivors will be able to get their own records, State Attorneys General can prosecute crimes, and we can take the DOJ to court for keeping critical files hidden.⚖️
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Absolute insanity. In just 40 minutes, the S&P 500 has now erased -$2 trillion in market cap. The entire post-Midterm Election rally has been erased in a matter of minutes. This is one of the fastest market cap losses in stock market history.
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Our new SHASTA-3 and SHASTA-4 data was published by @NEJM, showing percentage change in fasting serum triglyceride levels from baseline and acute pancreatitis risk reduction in adults with severe hypertriglyceridemia (sHTG).
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I’ve been quiet these days on the current events at @Alnylam. Lots of people asking me these days if/how/when the company will recover. Reminds me of October 2016 when revusiran showed a safety imbalance in the ill-fated ENDEAVOUR Phase 3 study. Stock lost 50-60% of its value, investors lost hope in RNAi. Within a year, APOLLO read out positively and the stock bounced back (and then some). So…. As people mull over the CardioTTRansform implications, 340B headwinds, payer dynamics, TRITON-CM…. I have ZERO doubt about Alnylam’s future bright prospects!
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BREAKING: Iran's Speaker of the Parliament responds to Vice President JD Vance after he blamed the Iran War for the Republicans' loss: "Losing gambler energy, can't walk away from the table... Why not say this to your boss?"
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$ANIP has launched a recommended offer to acquire Egetis Therapeutics for about $560 million, adding the approved rare disease drug EMCITATE. notreload.xyz/xy/anip-offers…
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$ONC Q3 BRUKINSA global revenue $1.4B ↑ 34%
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🚨 WOW. Gov. Ron DeSantis is GOING OFF right now post-blue tsunami: "I see the ad, 'so and so voted against releasing the Epstein Files.' I'm like, that's a bad vote. We ran as Republicans saying we need to do that. And you have people in Congress voting against release when the Attorney General said she had all the all this horrific stuff on her desk and that people are gonna be held accountable?!" "It's untenable when you have people going in trading stocks! I've never traded stocks since I've been in elected office. How do you have no investment acumen, and then all of a sudden get elected to Congress, and then you're outperforming Warren Buffett?" "I saw how they were running and it was a rejection of what was going on in DC."
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Look at that - our VP JD Vance was honest about why we lost. Will the message finally be heard?
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Replying to @goddek
Yep
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