Research Fellow, Neurological Foundation NZ Human Brain Bank
Joined October 2019
- Tweets242
- Following327
- Followers182
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Blake Highet retweeted
1/ We are excited to share our new paper in @JExpMed!
doi.org/10.1084/jem.20251245
Here we show that α-synuclein, a protein involved in Parkinson’s disease, triggers inflammation at CNS borders and impairs CNS clearance.
New perspective piece out in @FrontNeurol! We share our perspective from New Zealand's only post-mortem brain bank: the Neurological Foundation Human Brain Bank 🧠 (@NeurologicalNZ @cbrnewzealand). Read it here 👉 frontiersin.org/journals/neu…
Blake Highet retweeted
Effects of prolonged post-fixation on vascular biomarkers in postmortem human brains biorxiv.org/content/10.64898… #biorxiv_neursci
Blake Highet retweeted
I am hiring! If you enjoyed our recent publication (nature.com/articles/s41588-0…) and are interested in all things systems immunology, paediatric oncology and development, please apply below! Working in the wonderful @CRUK_CI and @Gilbertson_Lab
cam.ac.uk/jobs/research-assi…
Blake Highet retweeted
Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy, including postmortem PSP brain samples and a living human brain slice culture model
nature.com/articles/s41593-0…
Blake Highet retweeted
New study identifies the #hypothalamus as a deep brain stimulation target to promote walking recovery after #SpinalCordInjury in preclinical models and in a first-in-human feasibility study. #NeuroRehabilitation #Neuroscience #Neurotrauma @gcourtine
nature.com/articles/s41591-0…
Blake Highet retweeted
Happy to interrupt your election feed, to share our own findings. In an effort guided by @sophiejccaron and @JasonSynaptic we have made some interesting findings. Come and check it out.
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Blake Highet retweeted
A substantial reduction of #Alzheimers disease associated with semaglutide (Ozempic) in > 1 million people with Type 2 diabetes from a nationwide data resource
alz-journals.onlinelibrary.w…
Blake Highet retweeted
I think this should have been published in @NatureMedicine
Good catch for @alzdemjournals😍
Title: *****Insufficient***** evidence for an association between iatrogenic Alzheimer's disease and cadaveric pituitary-derived growth hormone
alz-journals.onlinelibrary.w… – at Carmel, IN
Blake Highet retweeted
Our paper exploring the antibody labelling signature of neurofibrillary tangle maturity in Alzheimer's disease is out now in @alzdemjournals.
doi.org/10.1002/alz.13922
Blake Highet retweeted
This was quite fun to co-write! New review on retrotransposons and endogenous retroviruses in neurodegenerative disorders from @joshdubnau and yours truly:
go.shr.lc/3wcE0Ls
Blake Highet retweeted
I'm delighted to share the latest work from our lab in which @HaoChingJiang1 and SungJin Park demonstrate that MS4A1/CD20 functions as a mammalian odorant receptor in a previously uncharacterized population of sensory neurons.
rdcu.be/dE8B7
Blake Highet retweeted
Since our lab tech Alyson is moving on to grad school (🎉), we are in need of a new tech. We are especially interested in folks who have tissue culture experience as the duties will be to generate primary rodent neurons. Please RT and DM me if interested. utah.peopleadmin.com/posting…
Congratulations @AliciaRavens !
New preprint 🚨 from the lab! Another paper years in the making from @AliciaRavens and Kaelan Sullivan (not on twitter). TDLR: we describe a new form of intercellular synaptic plasticity! It involves Arc and another cool protein IRSp53. 🧵/1 biorxiv.org/content/10.1101/…
Blake Highet retweeted
Exciting PhD project also available! Can *you* help treat X-linked #MND #FTD #ALS?? Domestic and international applicants considered. profiles.auckland.ac.nz/emma…. @FMHS_UoA @UoASciResFellow @FMHS_PGSA @ScienceUoA
Blake Highet retweeted
Calling UoA Biomed/ Neurosci students for Hons/ Masters projects in 2024. Help us make discoveries about #MND #ALS brain tissues. Pls retweet. mhsfaculty.auckland.ac.nz/pg… @FMHS_UoA @UoASciResFellow @FMHS_PGSA @ScienceUoA
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JONAS VINGEGAARD WINS THE STAGE 16 COMBLOUX ITT, DESTROYING BOTH THE CLOCK AND POGACAR! 🤯 He gained 1:38 on Pogacar in just 22 kilometers, absolutely shocking performance! #TDF2023
Blake Highet retweeted
Interested in understanding how neurons transport mRNAs in dendrites and control when and where they're used for local protein synthesis? My group is hiring a postdoctoral researcher!
elxw.fa.em3.oraclecloud.com/…
Blake Highet retweeted
openai package: #Rstats pkg interface to OpenAI API github.com/samterfa/openai
A significant proportion of my thesis work is now available at @journal_ad. Many thanks to my co-authors, as well as @NeurologicalNZ and @HRCNewZealand for funding this work, as well as my awesome co-authors including @JamesAWiseman and @hcmurray6! 🧠🔬pubmed.ncbi.nlm.nih.gov/3674…
Using single-plex in situ hybridization and a tissue-microarray method developed within @cbrnewzealand (nature.com/articles/s41596-0…), we identified a global decrease in PST expression across the AD brain, which negatively correlated with tau pathology.