@HillaryLinMD

Stanford-trained longevity physician. More years. More choices. Medicine, science & AI. Co-founder, Curator. Host of The Longevity Show.

 Manhattan, NY
hillarylinmd.com/links?utm_source=x&utm_medium=social&utm_content=profile
Joined July 2009
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  • Followers1.3K
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The most promising longevity drug isn't a peptide or metformin. It's the Shingles vaccine. New data shows it slows biological aging and lowers systemic inflammation for 4+ years post-shot. We are seeing a 20% reduction in new dementia diagnoses and a 25% lower risk of stroke. Stop waiting for a magic pill. One is already on the shelf. – at New York, USA
🤖 Made with AI
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Statin side effects? You still have options. Other pills, injections, a different statin or a lower dose may help. Oats and psyllium usually have smaller effects. Ask: “How far does my LDL need to fall, and what can I tolerate that gets me there?” Chart context: each drug used alone, rounded from separate trials. The spoken injection example also describes add-on treatment. These are LDL changes, not heart-attack risk reductions. Sources: doi.org/10.1161/CIR.00000000… pubmed.ncbi.nlm.nih.gov/3687… nccih.nih.gov/health/red-yea…
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Healthcare innovation loves a launch party. The real test is Monday morning. What are the outcomes? Can a clinician act without opening ten tabs? Does the patient know what happens next? Does anyone own the follow-through? Or did we just give healthcare another dashboard? I’ll be digging into this at The Fourth Effect’s Summit 2026 in NYC on October 27. “Health, Built to Hold” brings 25 builders, investors, and operators together to get specific about where good ideas stall and what needs to be built differently. A beautiful demo is nice. But can anyone use the thing? Details + application: summit.thefourtheffect.com/
Hillary Lin, MD, Founder, Curator, is speaking at The Fourth Effect’s Summit 2026: The Build, in New York City on October 27, 2026. Navy and gold speaker card with Hillary’s portrait. Hosted by Kirkland & Ellis.

ALT Hillary Lin, MD, Founder, Curator, is speaking at The Fourth Effect’s Summit 2026: The Build, in New York City on October 27, 2026. Navy and gold speaker card with Hillary’s portrait. Hosted by Kirkland & Ellis.

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“Powerhouse of the cell.” Mitochondria need a better job description. They help power a cell and, under certain conditions, help shut it down. Keeping you alive sometimes means a cell needs to go. Energy got all the PR. pubmed.ncbi.nlm.nih.gov/1590…
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After the AI math results, I don’t doubt it’ll take over medicine. Now get a straight answer from insurance. Please hold, Claude. openai.com/index/sharing-ai-…
Black poster with off-white type and a corded telephone. Text: ChatGPT diagnosed you. Claude confirmed it. Great. Now ask it to call your insurance. Signed Hillary Lin, MD.

ALT Black poster with off-white type and a corded telephone. Text: ChatGPT diagnosed you. Claude confirmed it. Great. Now ask it to call your insurance. Signed Hillary Lin, MD.

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Would we still call aging “just part of life” if we believed we could prevent it? We don’t know how far science can extend healthy life. How hard we try is a choice. Adapted from Nick Bostrom’s The Fable of the Dragon-Tyrant. nickbostrom.com/papers/the-f…
A dragon towers over a train in a mountain valley. Text: A FABLE ABOUT AGING They fed 100,000 people to a dragon. Every night. And called it normal. HILLARY LIN, MD 1 / 4

ALT A dragon towers over a train in a mountain valley. Text: A FABLE ABOUT AGING They fed 100,000 people to a dragon. Every night. And called it normal. HILLARY LIN, MD 1 / 4

A boy faces a crowded royal court. Text: It had seemed impossible. Every weapon failed. People built trains and jobs to feed the dragon. Then scientists found a material that could pierce its armor. A boy’s plea for his granny won support. HILLARY LIN, MD 2 / 4

ALT A boy faces a crowded royal court. Text: It had seemed impossible. Every weapon failed. People built trains and jobs to feed the dragon. Then scientists found a material that could pierce its armor. A boy’s plea for his granny won support. HILLARY LIN, MD 2 / 4

A king kneels beside an empty railway. Text: They killed the dragon. Years too late. Twelve years passed before the weapon was ready. The trains kept running. The king regretted feeding the dragon when he could have worked to defeat it. HILLARY LIN, MD 3 / 4

ALT A king kneels beside an empty railway. Text: They killed the dragon. Years too late. Twelve years passed before the weapon was ready. The trains kept running. The king regretted feeding the dragon when he could have worked to defeat it. HILLARY LIN, MD 3 / 4

A modern research bench. Text: THE LESSONS The dragon is aging itself. Past failure is no reason to stop trying. Treat illness. Aim to treat aging. Let real loss guide effort and funding. Act sooner. Plan for longer lives. Adapted from The Fable of the Dragon-Tyrant Nick Bostrom · nickbostrom.com HILLARY LIN, MD 4 / 4

ALT A modern research bench. Text: THE LESSONS The dragon is aging itself. Past failure is no reason to stop trying. Treat illness. Aim to treat aging. Let real loss guide effort and funding. Act sooner. Plan for longer lives. Adapted from The Fable of the Dragon-Tyrant Nick Bostrom · nickbostrom.com HILLARY LIN, MD 4 / 4

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Should we have the right to try medicines not yet FDA-approved? Does this open up the peptide Wild West? Work toward an osteoporosis cure. CAR-T targeting senescence in mice. Boston’s ongoing Translational Longevity Summit is filled with amazing discussions like these. I wish these conversations happened more often, and were more prevalent in the mainstream where it feels like we're being distracted by incremental changes. The longevity movement has arrived, and it is here to stay. Speakers and friends here: @jeannefrances @CamilloRicordi @aubreydegrey @IanHuyett @agingdoc1 @SumeraBukhari @Dr_ReenaB @MariZazzer. #Longevity #RightToTry
Five speakers sit on stage at the Translational Longevity Summit in Boston. The moderator at the right holds a microphone.

ALT Five speakers sit on stage at the Translational Longevity Summit in Boston. The moderator at the right holds a microphone.

Five summit attendees pose for a selfie in the conference lobby.

ALT Five summit attendees pose for a selfie in the conference lobby.

Four panelists sit below a slide titled Right to Try Laws in the USA: What’s Right, Wrong or Problematic, at the Boston summit.

ALT Four panelists sit below a slide titled Right to Try Laws in the USA: What’s Right, Wrong or Problematic, at the Boston summit.

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Should you have to be seriously ill before you can try an unapproved medicine? I wrote about the Right to Try debate in today’s Longevity Letter: what wider access could mean for peptides, and the safeguards I’d want. Subscribe free to read the full issue and get my take on new longevity research: newsletter.hillarylinmd.com/…

Should healthy people have the Right to Try?

People already buy unproven peptides. What would legal access change?

newsletter.hillarylinmd.com
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Longevity: medicine or marketing? NYC, Oct 14: I’m on stage at 6 PM at The Globe Bar. Doors 5:30. Mixer + startup pitches afterward. Building in health? You can still sign up to pitch. Tickets + pitch applications: medstartr.ai/events/longevit…
Hillary Lin, MD holding a microphone at a warm, dimly lit bar. Text: “Longevity. Medicine or marketing?” “Mixer + startup pitch night.” “Oct 14 · The Globe Bar, NYC.” @HILLARYLINMD.

ALT Hillary Lin, MD holding a microphone at a warm, dimly lit bar. Text: “Longevity. Medicine or marketing?” “Mixer + startup pitch night.” “Oct 14 · The Globe Bar, NYC.” @HILLARYLINMD.

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“Backed by science” is doing a lot of work when the study subjects had tails. Promising in mice ≠ proven to extend human life.
Black poster with large off-white type and a monochrome mouse with a long tail. Text: “You found a pill that promises longevity. There’s a study. There’s a graph. There’s a scientist with an impressive title. Before you reach for your credit card, check one more thing. Did the subjects have tails?” Footer: “Results in mice need testing in people.” Signed Hillary Lin, MD.

ALT Black poster with large off-white type and a monochrome mouse with a long tail. Text: “You found a pill that promises longevity. There’s a study. There’s a graph. There’s a scientist with an impressive title. Before you reach for your credit card, check one more thing. Did the subjects have tails?” Footer: “Results in mice need testing in people.” Signed Hillary Lin, MD.

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What happens when your patient is better at using AI than you are? Her Longevity tomorrow: women’s health + longevity, then me on AI across medicine at 5:19 PM. Hopefully you’re still awake 😂 NYC/virtual yourlongevity.ticketspice.co… Code: 100off
Portrait of Hillary Lin, MD beside an invitation to Her Longevity Summit: AI in Medicine, October 3 at 5:19 PM in NYC. Get tickets: herlongevity.org. Code: 100off.

ALT Portrait of Hillary Lin, MD beside an invitation to Her Longevity Summit: AI in Medicine, October 3 at 5:19 PM in NYC. Get tickets: herlongevity.org. Code: 100off.

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My genetic test seemed wrong. High cholesterol. Clear family history. No classic familial hypercholesterolemia variant. The result didn’t rule out inherited risk. And I still needed to treat my cholesterol.
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The vial says “not for human consumption”. People are injecting it anyway. “Research use only” does not prove what is inside or that it is sterile. With Dr. Mayoni Gooneratne and CareCore.
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Peptide FOMO is ahead of what I’m seeing in practice. Beyond GLP-1s, I see more hype than substance around many popular peptides. I’ll discuss the cautions with patients. That isn’t proof of the promise. With Dr. Mayoni Gooneratne. Hillary Lin, MD · CareCore – at New York, USA
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Your genetic heart-risk score may fit its training data better than it fits you. Many scores rely heavily on European-ancestry data. Ask how well yours was validated in people like you. youtube.com/watch?v=SG1aq_6v…
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A DEXA visceral-fat estimate doesn’t measure fat inside your liver. MRI-PDFF measures liver fat. Scarring is a separate question. Before buying a scan, ask what the result would change. Save the test guide. pmc.ncbi.nlm.nih.gov/article…
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ApoB, Lp(a), fasting insulin: different clues, not a single longevity score. The question is what you'd change because of the result. From my conversation with Zach Morris on Wealth Beyond Work.
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1% for longevity. Kyle Gonzalez's way of making exercise feel less daunting: think about the small share of your week it takes, then get specific about strength, cardio and recovery. From The Longevity Show.
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Hillary Lin, MD retweeted
Steven Wardell
@stevenwardellSep 8
Longevity has become big business. But is it becoming real medicine? Join us for the next NYC Health Innovaition Night on Wed. Oct. 14 featuring Guest of Honor @HillaryLinMD, host of the Longevity Show. Co-Hosted with @MedStartr's @alexbfair. Register now: eventbrite.com/e/new-york-he…

New York Health Innovation Night: Is Longevity Becoming Real Medicine?

An evening for innovators and investors in longevity & healthcare in New York to get together and talk about the future

eventbrite.com
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Should you test your biological age? Before you pay: how repeatable is the result, and what does a “younger” score actually prove? I'll discuss this at MVMNT, Sept 22–23 in Coronado. JOINME10: 10% off registration. theemvmnt.com/
Should you test your biological age? Before you pay, how much can you trust the result? A generic sample tube rests in an unbranded collection kit. Illustrative image, not a named product.

ALT Should you test your biological age? Before you pay, how much can you trust the result? A generic sample tube rests in an unbranded collection kit. Illustrative image, not a named product.

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A 2% health risk means 2 in 100 people. If you’re one of them, you don’t experience 2% of the consequences. The percentage describes a population. You live with the outcome. My conversation with Wei-Wu He: youtube.com/watch?v=SG1aq_6v…
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