The Hughes Lab at UCI. Developing blood vessels-on-a-chip and vascularized micro-organ (VMO) technologies to study vascular biology, cancer, and rare diseases.
Joined July 2020
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Check out our 2nd place @NikonSmallWorld video. Images in our vascularized micro-tumor device, it shows microvessels (red) forming over time and growing micro tumors (cyan) as they respond to contact with those vessels.
This time-lapse video shows a human micro-tumour growing over 10 days in a lab. 🤯
The tumour, in blue, grows with the support of vessels, shown in red.
Dr Stephanie Hachey and Dr Christopher Hughes were awarded second place for their video. @NikonSmallWorld @HughesLabUCI
Hughes Lab - UCI retweeted
Any cardiovascular postdocs looking for a job? A tenure-track faculty position for cardiovascular research is open at LSU Health Shreveport. Excellent research infrastructure in a collaborative and supportive environment. Great place to start a lab.
lsuhsc.edu/shv/CareerOpportu…
Hughes Lab - UCI retweeted
Excited to share our organoid model of vascularized stem cell islets.
Great teamwork led by @KVyNguyenNgoc and Yesl Jun. Thanks to @someshtweet, @HughesLabUCI, @steven_c_george, @ChristmanLab, @Hugh_Bender, @KravetsVira, @HIRN_CC . 1/4
biorxiv.org/content/10.1101/…
Our postdoc Steph is participating in the Anti Cancer Challenge at UCI this year to support junior scientists through @ARCS_OC. If you can take a couple minutes and make a donation to our cause Steph would be very grateful!
anti-cancerchallenge.rallybo…
Our postdoc Jenn presenting our work on the HHT-on-a-Chip model at last night’s MPS-World Summit! Thanks to everyone for stopping by!
Hughes Lab - UCI retweeted
Thrilled to have the opportunity to partner with @AracariBio @HughesLabUCI this week at #2022MPSWorldSummit to present a workshop to trainees discussing ways to allow physiology to inform development of micro physiological systems, and to demo the VMO platform!
Congratulations to our graduate students who presented an incredible joint poster at tonight’s MPS-World poster session!
We hope you were able to see our post doc Jenn this morning presenting a joint demo of our platform along with Will from @AracariBio!
Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi!
mpsworldsummit.com/mps-world…
In the first poster session, which will be Wednesday evening 6-8, we have several graduate student posters highlighting recent work on several of our healthy and disease #MPS models. Please stop by!
Are you in New Orleans this week for the MPS-World Summit? So are we! Most of our lab is in town and we are presenting several posters and talks about our work! Please come by and say hi!
mpsworldsummit.com/mps-world…
Thank you so much @HIRN_CC for highlighting our work to develop a Vascularized islet-on-a-chip model, the culmination of many years of work by our team!
@Hugh_Bender @msanderlab @steven_c_george @KimVyNguyenNgo1
Highlighting #HIRN manuscript:
A vascularized 3D model of the human pancreatic islet for ex vivo study of immune cell-islet interaction @biorxivpreprint tinyurl.com/vasc3D
@allysonshughes @KimVyNguyenNgo1 @steven_c_george @msanderlab @HughesLabUCI
#HIRNFundedResearch
Thank you! We are so excited to share this incredible work by our talented postdoc @Hugh_Bender!
Wonderful islet on a chip platform elevating islet culture conditions to include the #vasculature which provides functional support and models immune cell extravasation. Congratulations @Hugh_Bender @HughesLabUCI @msanderlab
Hughes Lab - UCI retweeted
We agree @BlumLabWisc ! It’s been fun to develop this together with @HughesLabUCI led by @Hugh_Bender .
Congratulations to our postdoc Satomi Matsumoto for receiving an Outstanding Talk award at this year’s #NAVBO @vascularbiology!
➡️Outstanding Talk in the Vascular Matrix Biology and Bioengineering Workshop
Suhaas Anbazhakan @suhaasaz
Kaveeta Kaw from @DiannaMilewicz Lab
Satomi Matsumoto from @HughesLabUCI
Scott Paulissen @ScottPaulissen
Michael Warkala @mwarkala
Thank you! So excited to share our ideas!
Partial #EndMT & #Angiogenesis
"Why do EndoMT transcription factors appear to be more essential in pathological angiogenesis compared to during development..."
An insightful review from Dr. Christopher Hughes lab🤓
@HughesLabUCI @FrontCellDevBio 2021
frontiersin.org/articles/10.…
Are you at @vascularbiology 2021 starting this week? Here’s where you can check out the latest work from the Hughes lab!
And last but certainly not least, don’t miss our illustrious leader Dr Chris Hughes when he co-chairs the Patterning and Morphogenesis I session tomorrow 10/27 at 2:00pm EST / 11:00am PST!
We’re so excited to present our latest work at @navbo #navbo2021 this week and hope you find this thread helpful in finding our research group members at the conference! Come say hi - we’d love to talk with you about our work!