@Icli_Lab

Noncoding RNAs| Angiogenesis| Tackling the role of microRNAs in the microvasculature in obesity & T2D| Assoc Prof @TuftsMedCenter| Harvard/BUMC/TTU

 MCRI- Boston,MA
tuftsmedicalcenter.org/physiciandirectory/basak-icli
Joined August 2022
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Excited to share our latest publication in ATVB! We show that SGLT2 inhibitors are not all alike. ahajournals.org/doi/10.1161/… @TuftsMedicalCtr @TuftsMedicine @TuftsMCResearch

SGLT2 Inhibitors Promote Diabetic Wound Healing Via AMPK/AKT/mTORC1-Regulated Endothelial Angioge...

BACKGROUND: Approximately 25% of patients with type 2 diabetes are at risk of developing diabetic ulcers, which can progress to amputations. A key challenge in diabetic wound healing is impaired...

ahajournals.org
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Excited to share that our lab received the Russo and the Springboard Awards in support of our research on RNA regulation, and obesity-associated cardiovascular disease. Thankful to my collaborators, trainees, and mentors for their support. @TuftsMedicine @TuftsMedicalCtr
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On the cover of the June issue of @Genes_MDPI: @Icli_Lab publication on Obesity and Heart Failure: Mechanistic Insights and the Regulatory Role of MicroRNAs mdpi.com/2073-4425/16/6/647 #TuftsMedicine
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Happy to share our latest publication from the Icli Lab @TuftsMCResearch @TuftsMedicalCtr @TuftsMedicine mdpi.com/2073-4425/16/6/647

Obesity and Heart Failure: Mechanistic Insights and the Regulatory Role of MicroRNAs

Heart failure (HF) remains a leading cause of morbidity and mortality worldwide, driven by diverse pathophysiological mechanisms. Among its major risk factors, obesity has emerged as a lobal public...

mdpi.com
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Congratulations Rachel Barber, MD candidate, for receiving the summer research award from Tufts Medical School to join our lab this summer! @TuftsMCResearch @TuftsMedicine
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Congratulations Furkan Bestepe, for presenting our latest research on the role of SGLT2 inhibitors in wound healing at the AHA Vascular Discovery Sessions in Baltimore. @AHAScience @VascularDiscovery2025 @TuftsMCResearch @TuftsMedicalCtr @TuftsMedicine
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So proud of our talented fellows Dr. Bestepe and Dr. Sahu. They both sucessfully presented their work during the MCRI retreat at Woodshole, MA and Furkan won the 1st place award in the fellows poster competition. 🧿 @TuftsMCResearch @TuftsMedSchool
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@Icli_Lab
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🎉 Congrats to Dr. Iris Jaffe (@IrisJaffeLab) of TUSM on her appointment to the AHA ATVB Women’s Leadership Committee! A leader in molecular cardiology and a dedicated cardiologist, Dr. Jaffe’s work is truly inspiring. #TuftsMedicine #AHA #Congrats
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What a remarkable young physcian-scientist. Dr. Sezan Vehbi’s time in my lab is coming to an end as she is moving on to residency. Thank you for all your hard work Sezan! Manuscripts to come soon from her amazing work. @TuftsMCResearch @Icli_Lab
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Our new paper made the cover @Icli_Lab Congratulations to @furkanbestepe for making the cover of the @FASEBorg Faseb Journal and George Ghanem, Sumedha Sahay for staining these beautiful sections of mouse dorsal wounds.
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@TuftsMCResearch @TuftsMedicalCtr @TuftsGSBS
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Basak Icli, MS., PhD. retweeted
Basak Icli, MS., PhD.@Icli_Lab9 Feb 2024
Please check out our latest publication from the @Icli_Lab focusing on microRNA regulation of angiogenesis and wound healing. @TuftsMCResearch @TuftsGSBS faseb.onlinelibrary.wiley.co…

MicroRNA‐409‐3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice

In the skin of patients with type 2 diabetes or in response to glucose in endothelial cells, miR-409-3p is significantly increased. This increase is associated with decreased activation of the...

faseb.onlinelibrary.wiley.com
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So proud of the recent @Icli_Lab alumni Carlos Sanchez and James Weston! Carlos will start Yale next year as a freshman and James will be starting his Medical school journey.
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Please check out our latest publication from the @Icli_Lab focusing on microRNA regulation of angiogenesis and wound healing. @TuftsMCResearch @TuftsGSBS faseb.onlinelibrary.wiley.co…

MicroRNA‐409‐3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice

In the skin of patients with type 2 diabetes or in response to glucose in endothelial cells, miR-409-3p is significantly increased. This increase is associated with decreased activation of the...

faseb.onlinelibrary.wiley.com
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Every once in a blue moon, things align perfectly and a manuscript is accepted with minor revisions. Can’t wait to share it once it is out soon! #Woundhealing #microRNAs @Icli_Lab
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@furkanbestepe @amandakmauro @mgood695
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Proud PI moment. The first postdoctoral fellow recruited to the @Icli_Lab a little over 2 years ago received the BCVS Travel Award. @furkanbestepe well deserved! @TuftsMedSchool @TuftsMCResearch #AHA23
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If you are attending #AHA23, stop by to hear more about the research in my lab Interorgan Cross-Talk in Cardiovascular Health and Disease Sunday Nov 12, 12:00- 1:15 PM “MicroRNA Regulation of Adipose Browning and Glucose Uptake Improves Cardiometabolic Disease” @TuftsMCResearch
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So proud of Furkan Bestepe and George Ghanem and all their hardwork. And welcome to the Icli Lab- Parul Sahu. Another wonderful retreat in the books. Thx to @IrisJaffeLab for spearheading another amazing retreat. #MCRI25
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