@JABLab3

Jen A-Brett MD PhD ATSF | 🫁 transplant & critical care | mechanisms of #chronic airway disease | cytokines and extracellular vesicles | @CSCTR_org President

 St Louis, MO
sites.wustl.edu/jablab
Joined August 2018
  • Tweets1.1K
  • Following787
  • Followers530
203Media
Congrats to @DuttSohini on her first publication in the lab! Stay tuned for her exciting work, much more to come! doi.org/10.1016/j.healun.202…
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Proud to celebrate Omar Osorio, PhD @JABLab3, a 2026 Henry Christian Award recipient from the American Federation for Medical Research. A national honor recognizing outstanding early-career research. #WashUMedPCCM @WashUDeptMed Read more>pulmonary.wustl.edu/omar-oso…
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I mean, who doesn’t think AP-1 is a central player? We agree 😁
Thomas Vierbuchen@TommyVierbuchenMar 26
Apparently it's AP-1 controls cellular memory week. Congrats @chris_cowley14 ! I guess I convinced you AP-1 is so interesting that you never need to work on anything else again... science.org/doi/10.1126/scie…

Distinctive DNA sequence features define epigenetic longevity of inflammatory memory

Tissues harbor memories of inflammation, which heighten sensitivity to diverse future assaults. Whether and how these adaptations are sustained through time and cell division remain poorly understo...

science.org
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AP-1 TFs control everything, example #312: nature.com/articles/d41586-0… nature.com/articles/s41586-0…

Remembrance of inflammations past

Nature - Chronic inflammation increases the risk of colon cancer. This inflammation drives epigenetic changes in the nucleus of stem cells that promote tumour formation.

nature.com
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Jen A-Brett retweeted
EXOKĒRYX@exokeryxMar 19
With just a few minutes of hands-on set-up, #DemeterEVPrep's hands-off, automated workflow isolates #EVs from up to 8 samples simultaneously. Visit us at @SelectBio's Next-Gen Instruments & Tools Driving EV Research 2026 to learn how Demeter EVPrep can speed your discovery. 🔗👇
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Abstract deadline is today!!! Join @CSCTR_org @AFMResearch for a fantastic program! csctr.org/annual-meeting/202…
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Minus the ‘and providers’ yes, you are correct.
Mark Cuban
@mcuban24 Dec 2025
If we fined insurers and providers $100 every time they over-billed, incorrectly denied care or misrepresented any amount of patient out of pocket, we could pay of the national debt They play on the fear and information asymmetry that exists in healthcare Break them up. Make them divest non insurance companies. And when we are done with the insurance companies , we go to the hospitals and then to the pharma wholesalers. Break em up. Make the markets efficient again.
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Jen A-Brett retweeted
Science News@SciencNewsJan 5
How to write an excellent Review article #PhD #phdlife #postdoc #Science #academia
Science News@SciencNewsJan 4
How to Write Your First Research Paper. #phdlife #PhD #academic #academictwitter #Science #research
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Jen A-Brett retweeted
Science News@SciencNewsJan 6
How to Be a Graduate Advisee
Science News@SciencNewsJan 4
How to Pick a Graduate Advisor #PhD #Science #academia #phdlife
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A previously unrecognized estrogen-dependent signaling pathway in the gut regulates visceral pain sensitivity in mice, according to a new Science study. The findings provide a pathway toward targeted therapeutic strategies. Learn more in a new #SciencePerspective: scim.ag/4j8UAA6
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Spermidine deficiency induces BNIP3/LC3B-mediated mitophagy in the salivary glands of accelerated aging mice sciencedirect.com/science/ar…
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Jen A-Brett retweeted
Dr. Dominic Ng
@DrDominicNgJan 2
New Cell paper from the team that discovered glymphatic clearance (how your brain removes waste during sleep). Sleep hours DIDN'T predict brain cleaning. Neither did REM or deep sleep. They found what actually matters - and why some sleeping pills might undermine it 🧵
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Organ-specific proteomic aging clocks predict disease and longevity across diverse populations nature.com/articles/s43587-0…
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Is fibroblast proliferation important in pulmonary fibrosis? Finally an answer - great paper by the super team of Christopher Molina,Tatsuya Tsukui, and Dean Sheppard #זScienceMatters #CureIPF jci.org/articles/view/191826
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Jen A-Brett retweeted
Lior Pachter@lpachter22 Nov 2025
Academic flexes that I dislike: 1/🧵
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Let’s be data driven! Supported access to professional coaching should be a standard part of every contract 😁
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Thanks for the shout out!
WashU Medicine Department of Medicine@WashUDeptMed14 Oct 2025
The @JABLab3 led by Jen Alexander-Brett, MD, PhD, @WashUMedPCCM analyzed COPD biospecimens released from cells into the airways. Findings help uncover cellular processes that drive chronic inflammation, tissue damage, and poor lung function. Learn more> internalmedicine.wustl.edu/b…
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🌎 Today is #WorldAlzheimersDay! Make a gift in honor of the 55 million people worldwide living with Alzheimer’s or another dementia and have DOUBLE the impact on accelerating research and helping provide vital care and support: bit.ly/4pDc2iY. #ENDALZ
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I recently learned that the novelist, Cormac McCarthy, spent several years at the Santa Fe Institute helping scientists write papers. His advice was condensed into a brief Nature column. The first three points, and some of the final points, are really good. (h/t @eryney_ok)
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Thanks for including us! @omar_ohhh @WashUMedPCCM @WashUDeptMed
EXOKĒRYX@exokeryx9 Sep 2025
Every #EV researcher knows - the quality of the sample is the quality of the experiment. If the sample quality is poor, the analytical result will be compromised. We discuss more with @JABLab3 in our latest blog post. #extracellularvesicles #EVs hubs.ly/Q03Hr9xv0

The Quality of the Sample is the Quality of the Experiment

The quality of the sample is the quality of the experiment

exokeryx.com
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