Neuroscientist/CellBiologist/SoftwareEngineer. Neuroimmune, Limbic Neurcircuitry. Multiphoton microscopy/fscv/electrophys/ML. he/him
Joined September 2019
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JordanYorgason retweeted
How do you put multiple optics in a row and align them so that their optical axes agree? This is a thread where I show you how I build a compact Alignment Laser Assembly– the companion to my "Alignment Crane" from a few months ago:
xitter.gq/TanFad/status/15591872…
1/? I've had a few people ask me why I prefer @Thorlabs posts over their cages. The argument for cages is self-defeating: supposedly they provide pre-aligned centration, but mechanical tolerances =/= optical tolerances. You end up having to put everything on kinematic mounts...
JordanYorgason retweeted
Interested in a summer position at UI? This is a great opportunity for rising junior and seniors at an accredited 4-yr college, with a competitive stipend!
Fellowships like these help folks get their foot in the door. I wouldn’t be here without one :) grad.uiowa.edu/biomedical-sc…
JordanYorgason retweeted
The Centanni Lab has an official website! centannilab.com/. Like the entire lab, it's a work in progress, but check it out if you want to learn more about the lab and what we're doing
JordanYorgason retweeted
Check out our most recent paper! I've been on the pre-print train for most things, but this one never made it there.
See Chris' tweet for the thread!
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JordanYorgason retweeted
Happy to share our latest pre-print! This subthreshold cation current is ~20 pA but provides ~10 mV depolarizing drive to fire.
Tonic GluD1 channel current is independent of G protein activity in the dorsal raphe nucleus biorxiv.org/content/10.1101/…
JordanYorgason retweeted
Here is a first of its kind visualization of evoked release from a dendritic process of a dopamine neuron:
JordanYorgason retweeted
Look at those extensions! Results from today’s microglia experiment. (Red was pre-drug exposure; green was 1.5 hours post-exposure.) #2photon #microglia
JordanYorgason retweeted
We will have fully funded positions open at all levels, and are looking to recruit new technicians, grad students and postdocs. Anyone interested please send a direct message or email me at drew.kiraly at gmail.
JordanYorgason retweeted
This was an amazing project to be a part of. I was mainly involved with the immunohistochemistry experiments to demonstrate the coexpression of Rho-1 and ChAT. It was a great experience and really helped sharpened my skills in confocal microscopy.
Happy to share our latest work: Modulation of dopamine release by ethanol is mediated by atypical GABAA receptors on cholinergic interneurons in the nucleus accumbens. Description in thread below. onlinelibrary.wiley.com/doi/…
JordanYorgason retweeted
Here is the early release on our latest work on the slow and strange alpha1-adrenergic receptor-EPSC, led by our very talented post-bac research interns!
jneurosci.org/content/early/…
JordanYorgason retweeted
My paper was published last week (things have been busy ;) in @JPhysiol ! Here I show how the α2δ‐2 protein contributes to signaling in two postsynaptic, calcium-dependent processes using electrophysiology and confocal microscopy. physoc.onlinelibrary.wiley.c…
JordanYorgason retweeted
New work from the lab, and first 1st author paper from @BrainyMariam, is online! Along with our esteemed collaborator @ACArnold_Lab, we show that astrocytes are critical for acute ethanol effects at CeA glutamate synapses. I’m super excited about this work… let me tell why 1/n🧵
My first first-author publication is finally in press on @
Neuropharmacology!!!
sciencedirect.com/science/ar…
#phdlife #phdchat #AcademicTwitter
JordanYorgason retweeted
Watch the 2021 Nobel Prize lectures online!
On Tuesday 7 December and Wednesday 8 December we will be streaming this year's Nobel Prize lectures here on Twitter. Join us for an in-depth look at the Nobel Prize achievements from our 2021 laureates.
#NobelPrize
JordanYorgason retweeted
LOOK AT THAT! A dopamine D2 dendro-dendritic synapse in the SNc! Years of work. Decades of beautiful physiology by many Williams lab members (@GantzStephanie, @mjbeckstead, Chris Ford + more).
Now we see what we knew was there.
Amazing!
link.springer.com/article/10…
JordanYorgason retweeted
Had a blast working on this with @ArruCarval_lab and @tyrell_turing: Promoting and Optimizing the Use of 3D Printed Objects in Spontaneous Recognition Memory Tasks in Rodents: A Method for Improving Rigor and Reproducibility: eneuro.org/content/early/202… @JudeFrie @InayatMehreen
JordanYorgason retweeted
Lots of scientists are amazing artists. But this thread isn't about them. It's about the rest of us, who are just trying to get through our methods figure so we can get back to showing you graphs.
First, a rat made entirely out of ovals:
(Morales-Botello et al., 2012)
(1/x)
JordanYorgason retweeted
This just happened:
colleague: "I am uncomfortable with the only woman in the room delegated to note taking, I can take over that task"
me: *happy tears* ❤️
JordanYorgason retweeted
So happy that our most recent work is out @PNASNews !! Thanks to all the @Nanopdics team @ITB_ULL @invest_ull @ULL pnas.org/content/118/35/e210… looking forward to finally celebrate in person with our fully vaxxed lab ❤️🎉🥂🍻
JordanYorgason retweeted
Our new suite of cAMP sensors now online: biorxiv.org/content/10.1101/…
Highlights:
- 10-fold increased sensitivity to cAMP, enables detection of physiological levels of NMs;
- Single/subcellular imaging reveal compartmentalized/heterogenous signaling in vivo during behavior...
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