research lab in immunogenomics at #McGill, studying genetics and functional genomics of immunodeficiencies, infectious and autoimmune diseases. #LanglaisLab
Joined July 2013
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David Langlais retweeted
1/ We report @ImmunityCP that the PD-1:PD-L1 axis promotes the development of B-cell memory and antibody responses in mice and humans. To our surprise, the pro-B-cell effect of PD-1 and PD-L1 is, at least partially, mediated in a B-cell-intrinsic manner. cell.com/immunity/abstract/S…
David Langlais retweeted
Protestation mondiale contre la fermeture de VEuPathDB
It appears #NIAID will shutter the genome data base we all use daily. This strikes me as a significant mistake that may well endanger much of our global progress. @BSPparasitology @AS_Para @ASTMH @TrendsParasitol @AmSocParasit @parasitesrule @PiParasitology
David Langlais retweeted
🎉Congratulations to @LanglaisLab and Michel L. Tremblay from @mcgillu for their award from @GenomeQuebec for their project "Establishing therapeutic cord blood-derived NK cells for hard-to-treat cancers through omics based and pharmacological activators" buff.ly/3Rere6k
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David Langlais retweeted
What a great way to start our Single Cell Education Workshop @SingleCellClubM ! Look forward to see the community later tonight at our “Get Clean, Or Get Lost” scQC Discussion hosted by @michaelluo @theresawonder @LanglaisLab !!
David Langlais retweeted
Fundraising for the Canadian Pulmonary Fibrosis Foundation to support pulmonary fibrosis research on behalf of the McGill Against PF Team: p2p.onecause.com/cpffwalks/t…
Thrilled that our project is funded!!
My lab and Dr Michel Tremblay's lab partner with Kanyr Pharma and the MUHC Cell Therapy Lab (Drs Pierre Laneuville and Linda Peltier) to establish therapeutic cord blood-derived NK cells for hard-to-treat cancers.
@mcgillu @McGillGenome
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David Langlais retweeted
Attend the Single Cell Discussion about “Quality Control of Single Cell Data - Get clean or get lost”.
The seminar will be about quality control parameters of SC sequencing data including sample preparation, ambient RNA, and doublet detection. Details in the poster below.
David Langlais retweeted
Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. cell.com/cell/fulltext/S0092…
David Langlais retweeted
Dear SC community. Join us on April 24th, 9am for a special session with @ParseBio at our single cell monthly seminar. Link on our website. singlecellclub.openscience.m…
@TheNeuro_MNI @LabStratton @LanglaisLab
David Langlais retweeted
You can read our latest paper :) A comment on: Extracellular Vesicles: Translational Agenda Questions for Three Protozoan Parasites. Published in Traffic - Wiley Online Library onlinelibrary.wiley.com/doi/…
David Langlais retweeted
Dear SC community. We have officially opened registration for our 2024 Single cell RNA sequencing workshop!
When: June 6th-7th 2024
Registration is free at singlecellclub.openscience.m….
The final agenda of the workshop will be provided soon
@TheNeuro_MNI @LabStratton @LanglaisLab
Congratulations @Tangye_Lab Thanks for having invited us to participate in this important study!
What does human CD4 do? By studying 7 ppl from 5 families with pathogenic homozygous CD4 mutations, our latest work by @GuerinAntoine6 @GarvanInstitute @UNSWMedicine describes non-redundant functions of CD4 in human immunity.
rupress.org/jem/article/221/…
David Langlais retweeted
🚨 Job opportunity, please RT! 🚨 My lab in Kyoto 🇯🇵 is looking to recruit 2 postdocs to work on comparative epigenomics, transposable elements, and/or related topics. Come work with @TakaInoue5 and me @Ashbi_KyotoU !
ashbi.kyoto-u.ac.jp/wp/wp-co…
David Langlais retweeted
The next MIM happy hour will be on March 19 at Pub l'Île Noire! See below for details
🍻
Le prochain 5 à 7 de MIM sera le 19 mars au Pub l'Île Noire! Voir ci-dessous pour plus de détails
Another amazing discovery from @BeziatV team in @casanova_lab. The 1st humans with inherited pre-TCRalpha deficiency, published in @ScienceMagazine. Grateful that my lab participated in this study!
@mcgillu @McGillGenome
1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/scie…
David Langlais retweeted
1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/scie…
David Langlais retweeted
Dear Single Cell community!
We are really excited for Dr. Iain Clark’s Killan lecturer talk. If you share the same interest in this GREAT single cell event, please register via QR code to attend in person or via Zoom.
@TheNeuro_MNI @LabStratton @easchurr @LanglaisLab @RIMUHC1
David Langlais retweeted
Dear SC community
Join us tomorrow Jan 31st, 9am EST for Dr Yue Li talk on Single-cell deconvolution by machine learning approaches. Zoom link available via our website at singlecellclub.ca.
@TheNeuro_MNI @LabStratton @easchurr @LanglaisLab
David Langlais retweeted
🔬 Day 1 of our #ParasiteEV series: Introduction to Extracellular Vesicles (EVs) in Parasite Biology. EVs, crucial for cellular communication, play pivotal roles in parasites. Let’s unveil their mysteries! 🦠🧫 #ScienceTwitter #EVs #ISEV (1/4)