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Ethan MacDonald, PhD, PEng Scientist, Philosopher and Enginerd

Calgary, Alberta, Canada
Joined September 2020
Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)Photo by ∑τћαη (@MEthanMacDonald)
Hermes Agent is shrinking the distance between a scientific idea and testing it. Thank you @NousResearch and @Teknium for building it.
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Weaponized incompetence is pretending not to know how to do something until the person affected by your failure does it for you. Strangely, the competence returns when the consequences do.
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Intelligence is on tap. Access is abundant. Discernment is not.
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Brains do not age uniformly. Our models should not pretend they do.
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We spent 70 years teaching computers to follow instructions. Now we’re teaching them to use judgment—and discovering that most “instructions” were undocumented judgment calls all along.
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The future arrived early and immediately asked us to verify we’re human.
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Is it reasonable to expect that at a conference centre with ~4000 participants, my laptop's Wi-Fi would work in the plenary?
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∑τћαη retweeted
Does brain aging always mean vessel loss? 🧠We found a surprising hypervascularization, driving cognitive decline & blood-brain barrier damage in aging. 👇🧵biorxiv.org/content/10.64898… Led by @MihailMuc
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∑τћαη retweeted
Happy to announce that Hermes Agent's repo just surpassed Anthropic's Claude Code repo
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If you are at #Sfn2025, come find us at the BRAIN Toolmakers Social (Sunday, 11/16, 7-9:30 pm). Learn about our simulation tools BMTK, SONATA, and VND - useful for building, sharing, and visualizing bio-realistic simulations of brain circuits! web.cvent.com/event/4a051497…
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The research team outing, they are really going places. We may have recruited a new member.
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Whole-genome analyses of whole-brain data: working within an expanded search space | Nature Neuroscience nature.com/articles/nn.3718
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Which foods have the highest amounts of NAD boosters? 1. NMN - broccoli, beetroot, green beans 2. NR - oranges, bananas 3. NAD+ - collard, spinach, parsley, cabbage But - 100 g of broccoli has only 14 mg of NMN vs. a dose that lowers cholesterol, BP & trigs of 1000 mg/day
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Short-chain fatty acids (SCFAs) promote gut health, lower inflammation and might promote longevity. New study reports sugary drinks are associated with fewer gut bacterial species that make SCFAs @Cell_Metabolism 🧵
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What a disappointment today. Can we not work together as North Americans to create an international jurisdiction force to address drug traffickers and other criminals that exploit the fact that we have separate countries and borders.. Instead of a trade war where everyone loses
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