🫀🧬 Cardiologist and genetic epidemiologist @PennCardiology and @VAPhiladelphia focused on translating human genetic insights into better cardiovascular care
Philadelphia, PA
Joined February 2008
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🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_:
jamanetwork.com/journals/jam…
Michael Levin retweeted
In @JAMA_current, we report that a single African ancestry-enriched CD36 variant (Y325*) contributes more to the population burden of dilated cardiomyopathy (DCM) in individuals of African ancestry than TTN truncating variants or other known DCM genes.
ja.ma/3Wy9k40
Michael Levin retweeted
Very excited to share our preprint led by @MGLevin @skoyamamd @jakob_woerner & with @damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations!
medrxiv.org/content/10.1101/… @medrxivpreprint
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Michael Levin retweeted
Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum | @NatureGenet nature.com/articles/s41588-0…
Michael Levin retweeted
Check out this editorial just published in @JAMACardio by our very own💫@PennCardiology fellow Anthony Anguiera & @sabramowitz_ under the mentorship of the one & only @MGLevin!
Unfolding the Link Between Transthyretin Stability and Survival
jamanetwork.com/journals/jam…
Michael Levin retweeted
New research by @damrauer & @MGLevin suggests that polygenic risk scores may provide conflicting results for detecting heart disease risk. spr.ly/6018scAup
Michael Levin retweeted
Now out in @JAMA_current: How well do individual risk estimates from different CHD polygenic scores agree? Grateful to work on this with a dream team of mentors and co-authors @damrauer @MGLevin @bpasaniuc @MarylynRitchie @dokyoon_kim @bvoight28 @BoulierKristin @karlkeat
🚨 Our work exploring polygenic risk scores for Coronary Heart Disease is now out in @JAMA_current and presented at #AHA24 by all-star @SarnoffCardio fellow @sabramowitz_:
jamanetwork.com/journals/jam…
13/ It was fun working with the team:
@sabramowitz_, @damrauer, @BoulierKristin, @karlkeat, @MarylynRitchie, @bvoight28, @bpasaniuc and everyone else. More exciting work to come!
14/ To learn more,
- Check out this editorial: jamanetwork.com/journals/jam…
- Listen to this AI-generated podcast summary: notebooklm.google.com/notebo…