Matthew Ziarnik (@MatthewZiarnik) header
Matthew Ziarnik (@MatthewZiarnik) profile picture

Matthew Ziarnik

@MatthewZiarnik

PhD candidate in Bioengineering | Polish

Joined February 2022
  • Tweets15
  • Following43
  • Followers2
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Matthew Ziarnik retweeted
Cell Reports (@CellReports) profile picture
Cell Reports@CellReports4 May 2022
Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry dlvr.it/SPlPHv
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Matthew Ziarnik retweeted
Eric Topol (@EricTopol) profile picture
Eric Topol
@EricTopol4 May 2022
As the virus evolves to be more fit over time, we're sequentially climbing the ladder of infectiousness
Image from Eric Topol (@EricTopol)
Eric Topol (@EricTopol) profile pictureEric Topol
@EricTopol4 May 2022
Omicron (BA.1) has rapidly evolved into other BA. variants with even more infectiousness and immune escape. Here's my preliminary summary based on the available data. BA.2.12.1's properties (currently 37% of new cases in the US) make it particularly formidable
Image from Eric Topol (@EricTopol)
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Thanks for all the positive responses on this poll! I am working on a video (or a short series of videos) which will go into more depth describing how T cells kill cancer and what is being shown in these videos.
Alex Ritter, PhD (@AlexRitterPhD) profile pictureAlex Ritter, PhD
@AlexRitterPhD29 Apr 2022
POLL: I'm thinking of creating a short video to explain the beautiful bit of biology we can observe in these images of immune cells killing cancer. Is this something you'd be interested in seeing? If "yes" please like - if "heck yeah!" please share 🙃
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Climate change will force new animal encounters — and boost viral outbreaks nature.com/articles/d41586-0… #ClimateEmergency
Climate change will force new animal encounters — and boost viral outbreaks

Climate change will force new animal encounters — and boost viral outbreaks

Nature - Modelling study is first to project how global warming will increase virus swapping between species.

nature.com
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Matthew Ziarnik retweeted
ASM (@ASMicrobiology) profile picture
ASM
@ASMicrobiology29 Apr 2022
Understanding how and why microbial pathogens emerge is more important than ever. @vilhelmiina_h journeys through pig guts, plastispheres and Floridian lagoons to explore what we can learn by studying pathogens on their home turf: asm.social/xG
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A look at tomorrow's front page.
Image from The Brown and White (@LUBrownWhite)
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Matthew Ziarnik retweeted
Lehigh University (@LehighU) profile picture
Lehigh University@LehighU27 Apr 2022
It's the fifth annual #LehighGivingDay! Giving Day is a 24-hour-long fundraising effort that rallies @LehighAlumni and the campus community together. This year, the goal is 100% completion on challenges/matches: bit.ly/3rV7ubh – at Bethlehem, PA
Image from Lehigh University (@LehighU)
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medrxiv.org/content/10.1101/…
SARS-CoV-2 testing of aircraft wastewater shows that mandatory tests and vaccination pass before...

SARS-CoV-2 testing of aircraft wastewater shows that mandatory tests and vaccination pass before...

Background Most new SARS-CoV-2 epidemics in France occurred following importation from abroad of emerging viral variants. Currently, the control of such risk of new variant importation is based on...

medrxiv.org
Northeastern Bioengineering Conference 2022 @Columbia
Image from Matthew Ziarnik (@MatthewZiarnik)
Fully vaccinated people had a reduced infectious viral load for the Delta variant of SARS-CoV-2 compared to unvaccinated people, according to a @NatureMedicine paper. In Omicron breakthrough cases, reduced viral load was only observed in boosted people. go.nature.com/3KLO8wS
Image from Nature Portfolio (@NaturePortfolio)
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We are thrilled to have a strong @LehighBioE presence in Lehigh's new Health, Science & Technology Building -Check it out! www2.lehigh.edu/news/new-hea… @lehighengineers @LehighResearch @pashucklab @TomasGF90 @anandjagota @HoltenNiels
New Health, Science and Technology Building: A Hub for Interdisciplinary Research

New Health, Science and Technology Building: A Hub for Interdisciplinary Research

The largest building Lehigh has ever built, HST is designed to encourage collaboration among faculty and students across disciplines.

news.lehigh.edu
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Matthew Ziarnik retweeted
Virology Tweets (@VirologyJ) profile picture
Virology Tweets@VirologyJ7 Apr 2022
In this highly cited study, researchers at @utmbhealth found that the African green monkey is an accurate model of human COVID-19 and provides new insight into several important aspects of COVID-19: virologyj.biomedcentral.com/… Blog: blogs.biomedcentral.com/on-h…
Image from Virology Tweets (@VirologyJ)
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Matthew Ziarnik retweeted
Denis Wirtz (@deniswirtz) profile picture
Denis Wirtz@deniswirtz4 Apr 2022
If you applied for but did not an NSF GRFP felloship, recycle your fellowship application! Here is a myriad of PhD fellowships you should consider apply to. Free, searchable, downloadable database of PhD fellowships: research.jhu.edu/rdt/funding…
Image from Denis Wirtz (@deniswirtz)
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Matthew Ziarnik retweeted
ASM (@ASMicrobiology) profile picture
ASM
@ASMicrobiology1 Apr 2022
The Omicron variant has quickly outcompeted the previously dominating Delta variant. This @JVirology study provides an overview of the mutations in the Omicron genome and the resulting changes in viral proteins compared to other COVID-19 strains asm.social/v0
Alterations in Nsp3, Nsp6, and Nsp8/Nsp12. (A) Schematic depiction of the domain arrangement of Nsp3. Ubl1, ubiquitin-like domain 1; ADRP, ADP-ribose-1″-phosphate phosphatase; SUD/MAC, SARS-CoV unique/macrodomain; Ubl2, ubiquitin-like domain 2; PL pro, papain-like protease; NAB, nucleic acid-binding domain; G2M, group 2-specific marker; TM, transmembrane domain; Y, Y domain. Mutations in the Omicron consensus sequence compared to Hu-1 are highlighted in red, and position is indicated with an arrow. (B) Alpha-fold prediction of the Nsp6 structure. Regions that are altered in the Omicron VOC are highlighted in red. Respective amino acid deletions (positions 105 to 107) or changes (I189V) are labeled in the box. (C) Structural representation of the complex between Hu-1 Nsp8 (tan) and Nsp12 (blue) derived from cryo-EM data (PDB 6YYT). The alteration in the Omicron VOC at the interface is highlighted in red (P323L).

ALT Alterations in Nsp3, Nsp6, and Nsp8/Nsp12. (A) Schematic depiction of the domain arrangement of Nsp3. Ubl1, ubiquitin-like domain 1; ADRP, ADP-ribose-1″-phosphate phosphatase; SUD/MAC, SARS-CoV unique/macrodomain; Ubl2, ubiquitin-like domain 2; PL pro, papain-like protease; NAB, nucleic acid-binding domain; G2M, group 2-specific marker; TM, transmembrane domain; Y, Y domain. Mutations in the Omicron consensus sequence compared to Hu-1 are highlighted in red, and position is indicated with an arrow. (B) Alpha-fold prediction of the Nsp6 structure. Regions that are altered in the Omicron VOC are highlighted in red. Respective amino acid deletions (positions 105 to 107) or changes (I189V) are labeled in the box. (C) Structural representation of the complex between Hu-1 Nsp8 (tan) and Nsp12 (blue) derived from cryo-EM data (PDB 6YYT). The alteration in the Omicron VOC at the interface is highlighted in red (P323L).

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