Nick Phillips retweeted
Our new arXiv paper: We built a generative AI model of blood glucose levels from 10 million continuous glucose monitoring measurements of 11,000 people from the Human Phenotype Project
We show that our model can predict clinical parameters such as liver-related parameters, blood lipids, and sleep-related indices. The model can also predict onset of future health outcomes even 4 years in advance, as well as outcomes of randomized clinical trials
We also integrated dietary data into the models and show that the enhanced model can accurately generate blood glucose levels using only dietary intake data, simulate outcomes of dietary interventions, and predict individual responses to specific foods.
The model also performs well on 15 different external datasets from 5 different geographical regions and 6 different continuous glucose monitoring devices
Paper: arxiv.org/abs/2408.11876
Data: humanphenotypeproject.org/
Great work led by @GLutsker, Gal Sapir, @nastya_godneva, @smadarshilo, @H_Rossman in collaboration with @SamochaBonetD and @nvidia researchers @GalChechik @MannorShie @eli_meirom
Nick Phillips retweeted
Are there universal laws driving complex systems dynamics across scales? What kind of general theory connects fluctuations in microbiomes, rainforests or economic and urban systems? Check this @PNASNews paper by ashish george & @Jp_odwyer @sfiscience pnas.org/doi/abs/10.1073/pna…
Nick Phillips retweeted
Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling dlvr.it/St16Cg
Nick Phillips retweeted
How precise are noisy #morphogen gradients in #tissue #patterning?
It turns out that the positional information they convey to #cells in the #neuraltube is much more accurate than previously estimated!
Our new #devbio paper is out in @NatureComms: rdcu.be/cH8Fx
Nick Phillips retweeted
🥳 Just awarded a Synapsis foundation grant !
➡️Open PhD student position
🔬🧠Protein homeostasis in live single human neurons in healthy/ND disease.
If you feel 🤩 tell me and apply at @epfl_edcb or EDMS PhD program. Thx for RT
Nick Phillips retweeted
We're gearing up for the final #PeakEnsemble of the year!
Join us next month to hear from @NPSysBio of @Hopitaux_unige! 🇨🇭
#AI #datascience #datacommunity
Nick Phillips retweeted
Analyses of the #CircadianOscillator at the single-transcript level --> bit.ly/3qMJt2P from @Naefelix @EPFL_en
#SingleCell #CircadianClock #QBio #transcription
Nick Phillips retweeted
OscoNet: Inferring oscillatory gene networks @MagnusRattray @Boukouva1Alexis biorxiv.org/content/10.1101/…
Nick Phillips retweeted
Our tightly collaborative work with @Naefelix and @NPSysBio is out - Transcriptional memory varies widely between genes and scales with expression variability - may play a role in tissue patterning
nature.com/articles/s41467-0…
Nick Phillips retweeted
Simone Vezzani particle rendering a portrait from the Bode-Museum using Redshift.
Nick Phillips retweeted
"All models are wrong, but some are useful" used to be my favorite quote regarding the use of models (applies equally to biological & mathematical models), but it is fast losing out to "A model is a lie that helps you see the truth". (Still need to figure out who said the latter)
Nick Phillips retweeted
A day to reflect on this continent's history, and to remember not to take peace for granted. That a German can stand in a British lecture theatre with Russian, French and American students, and nobody really cares where anyone is from. Grateful.
Nick Phillips retweeted
Climbing Perch:
🐟Crossing the road
🐟Have an accessory air breathing organ (labyrinth) which allows them to tolerate low oxygen levels and short periods out of water
🐟They move over land between pools by levering themselves along using long robust spines on their gill covers
Nick Phillips retweeted
PhD position open in my lab at EPFL through @epfl_edcb programme: understanding fate choice and cell type commitment during nervous system development using single cell genomics (RNA velocity and more...) gioelelamanno.com/people/ope… @epflSV @EPFL
Nick Phillips retweeted
Interdisciplinary PhD position with Val Wilson and myself @crm_edinburgh, on "Modelling cell state transitions in differentiating embryonic stem cells". Theory, Experiment, and Inference! @EastbioDTP competitively funded. Apply by Dec 5th.
eastscotbiodtp.ac.uk/modelli…
Nick Phillips retweeted
Our review on dynamic gene expression regulation over the 24-hour day is out! "Rhythms of the Genome: Circadian Dynamics from Chromatin Topology, Tissue-Specific Gene Expression, to Behavior"
cell.com/trends/genetics/ful…
Nick Phillips retweeted
Check out our latest paper in bioRxiv: live monitoring of transcription in dividing cells reveals a range of transcriptional memory duration - scaling with expression variability at the population level. Great collaboration with @NPSysBio and @Naefelix
biorxiv.org/content/early/20…
Nick Phillips retweeted
John Tyler, America’s tenth president, was born in 1790. He has two living grandchildren.
Yes, grandchildren.
Nick Phillips retweeted
Fast GPLVM with priors for single cell leveraging #gpflow #TensorFlow with @MagnusRattray @AhmedSumon00 xitter.gq/biorxiv_bioinfo/status…
GrandPrix: Scaling up the Bayesian GPLVM for single-cell data biorxiv.org/cgi/content/shor… #biorxiv_bioinfo


























