PEDS is an Oxford University Press journal publishing the latest research in #proteinengineering, #proteindesign and #proteinscience.
Joined January 2020
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PEDS: Protein Engineering, Design & Selection retweeted
We are recruiting: @ProtEngDesSel is looking for an Editor-in-Chief to lead the journal into the future! If you’re a leader in protein engineering with a strong vision for the field, we want to hear from you.
View more details and apply: oxford.ly/3Y3Hzxg
#JournalEditor
ALT PEDS is now recruiting for a new Editor-in-Chief. Learn more and apply today, featured with the journal's cover.
PEDS: Protein Engineering, Design & Selection retweeted
New article alert!
@CarlDenard et al. present a series of YESS plasmids that provide a robust platform to observe and quantify PTM-enzyme activity in yeast.
Modular and integrative activity reporters enhance biochemical studies in the yeast ER academic.oup.com/peds/articl…
PEDS: Protein Engineering, Design & Selection retweeted
Check our latest work about shortest path method (SPM) webserver for computational enzyme design by @GuillemCasaF J Casadevall @CrisDuran25 @silviaosu in @ProtEngDesSel
#IQCCpaper @TCBioSys @UdGRecerca
academic.oup.com/peds/articl…
PEDS: Protein Engineering, Design & Selection retweeted
It's been three years since the revolutionary announcement of AlphaFold2, and @Chica_lab and I discuss at @NatureBiotech whether such a moment will take place in protein engineering too. Optimistic for the future - but with loads of challenges to address!
nature.com/articles/s41587-0…
PEDS: Protein Engineering, Design & Selection retweeted
🎉 Exciting News! Our paper "TIMED-Design: Flexible & Accessible Protein Sequence Design with Convolutional Neural Networks" has been accepted for publication in Protein Engineering, Design and Selection!
👉 Try the UI: pragmaticproteindesign.bio.e…
📖 Paper: academic.oup.com/peds/advanc…
PEDS: Protein Engineering, Design & Selection retweeted
We are thrilled to present a new #enzyme to the world, the first shown to break the man-made carbon-silicon bonds in #siloxanes, which are persistent in the environment.
caltech.edu/about/news/teach…
PEDS: Protein Engineering, Design & Selection retweeted
Happy to have one of my first projects at MSR out at @ProtEngDesSel!
With @nc_znc and Hugh Yeh, we feed outputs from a pretrained masked language model into structure-GNN to learn a joint embedding for protein representation.
academic.oup.com/peds/articl…
PEDS: Protein Engineering, Design & Selection retweeted
I'm excited to present @FrancPesce's work on developing, applying & testing a method to design intrinsically disordered proteins 🍝
While there has been much work on design methods for folded proteins, much less has been done for IDPs. 1/n
doi.org/10.1101/2023.10.22.5…
Design of intrinsically disordered protein variants with diverse structural properties biorxiv.org/cgi/content/shor… #biorxiv_biophys
PEDS: Protein Engineering, Design & Selection retweeted
With @nicdou and #JoellePelletier, we recently reviewed the state of knowledge in ‘dynamic engineering’, i.e. the rational modification of #protein dynamics to alter #enzyme function! doi.org/10.1093/protein/gzac…
#ProteinEngineering
@ProtEngDesSel @NSERC_CRSNG @inrsciences @UMontreal
PEDS: Protein Engineering, Design & Selection retweeted
#finally caught up with @CarolynBertozzi and Jennifer @doudna_lab #nobelweek #chemnobelles @NobelPrize
PEDS: Protein Engineering, Design & Selection retweeted
Check out our latest review paper, "Engineering the Enzyme Toolbox to Tailor Glycosylation in Small Molecule Natural Products and Protein Biologics" by @syntheticsara, @SynBioDulce, @IfthihaMohideen, and me!
🎉
Published in @ProtEngDesSel
doi.org/10.1093/protein/gzac…
#glycotime
PEDS: Protein Engineering, Design & Selection retweeted
Engineering the Enzyme Toolbox to Tailor Glycosylation in Small Molecule Natural Products and Protein Biologics dlvr.it/SdZ3qB
PEDS: Protein Engineering, Design & Selection retweeted
Browse the latest article addition to the Hot Topics collection of reviews from @ProtEngDesSel. The article dives into how #protein stability, dynamics, & function are intricately linked. View the full collection of free-to-read articles: bit.ly/3BJW1On @Chica_lab
PEDS: Protein Engineering, Design & Selection retweeted
Happy to share our latest work! Generation of high-affinity TCR-like antibodies by use of phage display and structural models @rahelfrick @geiralo @jeffreyjgray @JCoDiRC
New article alert! Geir Åge Løset (@biovitenskap), in collaboration with @jeffreyjgray, show how structural models and phage display enable the generation of TCR-like antibodies with picomolar affinities.
academic.oup.com/peds/advanc…
PEDS: Protein Engineering, Design & Selection retweeted
Join us for the 4th @PEC_conference!
Abstract Deadline: Apr. 29 bit.ly/PECAbstract
Speakers: Andreas Plückthun, Bill DeGrado, Birte Höcker, Basil Hubbard, Liz Meiering, @keating_lab @befcorreia @PPYlabGT @DodaniLab @HuiminZhaoLab @ChemSynthBiol @DekWBristol @BudisaNed
PEDS: Protein Engineering, Design & Selection retweeted
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Save the date!
Happy to announce the 4th Protein Engineering Canada (PEC) Conference, which will be held at Concordia University in Montreal on June 21-23, 2022. This is an in-person event, with emergency backup plan to go fully virtual if conditions necessitate.
PEDS: Protein Engineering, Design & Selection retweeted
Check out my recent paper with @LauraItzhaki Here we show that a series of binding peptides can be grafted into the protein loop of a repeat protein to confer nanomolar affinity for an E3 ubiquitin ligase.
academic.oup.com/peds/articl…
PEDS: Protein Engineering, Design & Selection retweeted
Excellent work showing how a single mutation can lead to low-T thermoadaptation by changing protein rigidity!
Am I spotting curved T-dependencies / negative activation heat capacities in the low-T adapted variants? 🧐❄️🥶
Increasing loop flexibility affords low-temperature adaptation of a moderate thermophilic malate dehydrogenase from Geobacillus stearothermophilus academic.oup.com/peds/articl…
PEDS: Protein Engineering, Design & Selection retweeted
Discounted registration ends on Nov 30 for #Biomolecule Modeling & #ComputationalDesign!
Explore #StructuralBiology #DeepLearning for #DrugDiscovery & connect with leading journal Editors like @OxUniPress @ProtEngDesSel Roberto Chica @OxUniPress
keystonesymposia.org/KS/Onli…
PEDS: Protein Engineering, Design & Selection retweeted
📢New @CRC1357 publication @ProtEngDesSel: How long does it take to degrade PET with a PET degrading enzyme? Weigert, Gagsteiner, Menzel, Höcker provide "A versatile assay platform for enzymatic poly(ethylene-terephthalate) degradation“ to measure it.academic.oup.com/peds/articl…
