@RFreireLab

Replicative Stress and Tumorigenesis Lab. Research Unit-Hospital Universitario de Canarias. Fond of photography.

 Tenerife-Spain
Joined November 2019
  • Tweets128
  • Following164
  • Followers294
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Raimundo Freire retweeted
Veronique Smits@VSmitsLabOct 13
Hoy he participado en una charla de divulgación científica de Chicas con Cienci@ULL en el IES Anaga 🧬🔬 ¡Gracias por la invitación y por acercar la ciencia a las nuevas generaciones! @CienciaULL
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Raimundo Freire retweeted
Román Gonzalez-Prieto@HombreRRoSep 23
Pre-print Alert! Spearheaded by @emilyshidalgo, RNF25 ubiquitin E3 activity modulates the three processes of the central dogma of Molecular Biology: DNA replication, Transcription and Translation by promoting the rapid degradation of different substrates biorxiv.org/content/10.64898…

RNF25 Ubiquitin E3 activity Safeguards Genome Integrity by Modulating DNA Replication, Transcript...

The human genome encodes several hundreds of ubiquitin E3 enzymes, most of which have poorly understood biological roles. In search for novel ubiquitin E3 enzymes involved in DNA damage tolerance, we...

biorxiv.org
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Very happy to see this article published after years of teamwork. Thanks to everybody who contributed. nature.com/articles/s42003-0…

Impaired protein translation inhibits DNA replication by a Claspin-Chk1-Rif1 pathway

Communications Biology - Characterisation of the response to protein synthesis inhibition identifies a Claspin/Chk1/Rif1 pathway that couples translational attenuation to suppression of DNA...

nature.com
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Raimundo Freire retweeted
Veronique Smits@VSmitsLabJul 20
Our collaboration with @RFreireLab on the #PID2025 project UPGRADE has been funded! 🎉 Many thanks to the reviewers and evaluation committee at @AgEInves for their support.
Agencia Estatal de Investigación@AgEInvesJul 16
Publicada Propuesta de Resolución Provisional de la convocatoria Proyectos Generación de Conocimiento #PID2025 para impulsar la #investigación, generación de #conocimiento y búsqueda de soluciones a los grandes desafíos de la sociedad. 🔗aei.gob.es/noticias/convocat…
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Nuestro proyecto #PID2025 UPGRADE, en colaboración con @VSmitsLab, ha sido financiado! 🎉 Muchas gracias a los evaluadores y la comisión de @AgeInves por su apoyo.
Agencia Estatal de Investigación@AgEInvesJul 16
Publicada Propuesta de Resolución Provisional de la convocatoria Proyectos Generación de Conocimiento #PID2025 para impulsar la #investigación, generación de #conocimiento y búsqueda de soluciones a los grandes desafíos de la sociedad. 🔗aei.gob.es/noticias/convocat…
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A brand new doctor since last Friday: great PhD defense by @grodtor , co-supervised by @VSmitsLab. Thanks for the very interesting discussion with @PabloHuertasLab, @jonaygl and Rosa Barrio. Congratulations @grodtor !
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Estás interesado/a en solicitar una ayuda para hacer un postdoctoral por 2 años en un trabajo aplicado en colaboración con la industria? Manda un mail con tu CV a [email protected] .
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Raimundo Freire retweeted
Veronique Smits@VSmitsLabApr 20
Our latest publication by @Jessel_ap is out in @CellReports. We show that DNA damage in late mitosis triggers an ATM-dependent increase in RNF126 and BRAP, which promote cell survival under these conditions. With help from @RFreireLab. doi.org/10.1016/j.celrep.202…
Cell Reports@CellReportsApr 17
RNF126 and BRAP safeguard genome integrity after DNA damage in late mitosis dlvr.it/TS5VqX

RNF126 and BRAP safeguard genome integrity after DNA damage in late mitosis

Ayra-Plasencia et al. identify ATM-dependent upregulation of RNF126 and BRAP protein levels upon irradiation in late anaphase/telophase. These E3 ligases are required for the DNA damage response and...

cell.com
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Raimundo Freire retweeted
Cell Reports@CellReportsApr 17
RNF126 and BRAP safeguard genome integrity after DNA damage in late mitosis dlvr.it/TS5VqX

RNF126 and BRAP safeguard genome integrity after DNA damage in late mitosis

Ayra-Plasencia et al. identify ATM-dependent upregulation of RNF126 and BRAP protein levels upon irradiation in late anaphase/telophase. These E3 ligases are required for the DNA damage response and...

cell.com
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Raimundo Freire retweeted
Veronique Smits@VSmitsLabFeb 25
Fantastic seminar by Marcel van Vugt yesterday. And it was great to catch up. Thanks for stopping by! @ITB_ULL
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Durante las #SCIC25 de la @agenciaiisi, recibimos a estudiantes de bachillerato en nuestro laboratorio. Conocieron de cerca la biología molecular y celular y se informaron sobre la carrera científica 🔬🧫👨‍🔬 #somosciencia @cienciacanaria @VSmitsLab
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Raimundo Freire retweeted
Veronique Smits@VSmitsLab6 Nov 2025
It was a pleasure to host Miguel Blanco @DNA_Repair_USC in the lab today. Thanks for a great seminar Miguel!
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Raimundo Freire retweeted
Veronique Smits@VSmitsLab8 Nov 2025
Well done @CintiaFonRod on a great PhD defence! Thanks to the committee for their time and feedback. @DNA_Repair_USC @lblancodavila1 @DDRRepair Congratulations Dra. Fonseca Rodríguez! 🎓 🍾
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Raimundo Freire retweeted
Veronique Smits@VSmitsLab14 Mar 2025
Happy to share our latest publication by @YerayHdezReyes and @CintiaFonRod in @JMolBiol, highlighting two RNA helicases, DDX37 and DDX50, that ensure genome stability by preventing transcription-dependent R-loop formation. With help from @RFreireLab. doi.org/10.1016/j.jmb.2025.1…
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Our latest Method paper in @PLOSONE describing different approaches to study ATXN3 aggregation. Great work by Greg and Cristi. doi.org/10.1371/journal.pone…

Biochemical analysis to study wild-type and polyglutamine-expanded ATXN3 species

Spinocerebellar ataxia type 3 (SCA3) is a cureless neurodegenerative disease recognized as the most prevalent form of dominantly inherited ataxia worldwide. The main hallmark of SCA3 is the expansion...

journals.plos.org
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Raimundo Freire retweeted
Veronique Smits@VSmitsLab13 Dec 2024
Research Unit Christmas lunch🥂🎄🧑‍🎄🍕
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Raimundo Freire retweeted
Abraham Acevedo@Acevedo_lab4 Nov 2024
Job alert! Se ofrece contrato de doctorado asociado a proyecto (FPI) centrado en el estudio del papel central de TDP-43 en la ELA. Buscamos personas con entusiasmo y ganas de trabajar interesadas en el estudio de mecanismos moleculares de neurodegeneración en modelos de ratón
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Raimundo Freire retweeted
Abraham Acevedo@Acevedo_lab4 Nov 2024
Job alert 🚨 Fully funded PhD position associated with a project (FPI) focused on the study of the central role of TDP-43 in ALS. We are looking for enthusiastic people interested in the study of molecular mechanisms of neurodegeneration using innovative mouse models.
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Happy to see our review on ATXN3 published in Expert Reviews in Molecular Medicine. Great efford by @EsperanzaHC_ and X-less Greg. bit.ly/47MWj8m
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Raimundo Freire retweeted
Abraham Acevedo@Acevedo_lab14 Aug 2024
🚨PhD position alert🕵️ We are looking for a motivated PhD candidate to join our laboratory in Tenerife, Spain, with a 4 year fully funded PhD contract (FPI) associated with a project focussing on understanding the role of TDP-43 in amyotrophic lateral sclerosis (ALS).
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