Seth Robia (@SethRobia) profile picture

Seth Robia

@SethRobia

Professor, Loyola University Chicago, Department of Cell and Molecular Physiology

 Illinois, USA
robialab.org
Joined November 2022
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  • Following111
  • Followers106
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Photo by Seth Robia (@SethRobia)Photo by Seth Robia (@SethRobia)Photo by Seth Robia (@SethRobia)Photo by Seth Robia (@SethRobia)Photo by Seth Robia (@SethRobia)Photo by Seth Robia (@SethRobia)
Also… my little project was just published!!! Thank you all my amazing collaborators who made it possible! link.springer.com/article/10…
The Quaternary Structure of the Sodium Pump Regulatory Complex Is Altered by Mutations of a Site...

The Quaternary Structure of the Sodium Pump Regulatory Complex Is Altered by Mutations of a Site...

Molecular Neurobiology - The sodium–potassium ATPase (Na+/K+-ATPase, NKA) is a P-type ATPase that plays a central role in cell physiology, establishing Na+ and K+ gradients across the plasma...

link.springer.com
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❤️🫀In this JBC paper about dilated cardiomyopathy, researchers "postulate that impaired responsiveness to physiological stress contributes to arrhythmogenesis in human carriers of the R14del mutation." ow.ly/tawg50V0CR4 #ValentinesDay #AmericanHeartMonth #OurHearts @asbmb
A schematic diagram displaying how PLB phosphorylation and DCM mutations of PLB, R14del and R9C, impact the equilibrium binding of monomeric PLB (PLB1) with pentamers (PLB5) and SERCA (PLB-SERCA) by decreasing the rate of PLB monomers unbinding from pentamers.

ALT A schematic diagram displaying how PLB phosphorylation and DCM mutations of PLB, R14del and R9C, impact the equilibrium binding of monomeric PLB (PLB1) with pentamers (PLB5) and SERCA (PLB-SERCA) by decreasing the rate of PLB monomers unbinding from pentamers.

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Check out Sean's new paper! A mutation of phospholamban reduces the heart's ability to respond to stress. jbc.org/article/S0021-9258%2… @SeeinClearly1 @Allenctteng @PKH_Lab @A_Gramolini @CatMak23
Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic...

Dilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic...

The sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is a membrane transporter that creates and maintains intracellular Ca2+ stores. In the heart, SERCA is regulated by an inhibitory interaction with...

jbc.org
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Attention undergrads! Join us in Chicago this summer for #cardiovascular research! Hands-on experience, seminars, social activities, free pizza, and attend a Nat'l Conference! Send application to [email protected]. Supported by @AHAScience. @LoyolaChicago, @CURinAction #cardiotwitter
Image from Jonathan Kirk (@jonathankirk)
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The search is on.... We are recruiting at the assistant professor level! Come join us!!! Assistant Professor job with Loyola University of Chicago - Cell and Molecular Physiology Department | 12818067 (nature.com)
Nature

Nature

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest ...

nature.com
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Attention Chicagoland cardiovascular basic science researchers! Join us for the 3rd annual CRCRS on July 12th, hosted by the Center for Cardiovascular Research at UIC. See below for abstract submission details. For more info, visit barefieldlab.org/crcrs
Image from Dave Barefield, PhD (@BarefieldD)
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Congratulations to Sean Cleary @SeeinClearly1 on the new hood and the new paper! You had a great idea and turns out you were right! jbc.org/article/S0021-9258%2… Thanks to our great collaborators who helped us figure out how it works @khandeliagroup @fonseca_lennane @JaroslavaNKA
Image from Seth Robia (@SethRobia)
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New in JBC press: "Scientists' results provide new insight into a novel allosteric pathway connecting the ATP binding site with distant Ca2+ binding sites." Learn more: jbc.org/article/S0021-9258(2…
Figure 2. Effects of ATP and PLB on structure of SERCA Ca2+ transport sites.

ALT Figure 2. Effects of ATP and PLB on structure of SERCA Ca2+ transport sites.

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Please share! Apply now for our new Masters Degree in Proteomics (mscaps.sites.luc.edu/)! Watch the video ad for the innovative program here: youtube.com/watch?v=gTN3ZNo4…. Please DM me with any questions.
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biophysics-jobs.careerwebsit…
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All of Twitter is invited to the PhD defense of Sean Cleary (@SeeinClearly1) Mon June 12, 2023 at 10:30a CDT in the CTRE auditorium. Sean will be revealing exciting secrets of the universe, so be sure to attend in person or by zoom: luc.zoom.us/j/83958656026
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Congratulations Dr. Cleary!
Image from Seth Robia (@SethRobia)
Image from Seth Robia (@SethRobia)
Image from Seth Robia (@SethRobia)
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The US pandemic response effect on learning — in one gif! us11.campaign-archive.com/?u…
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Attention undergrads! Join us in Chicago this summer to learn and perform #cardiovascular research. Hands-on experience, seminars, social activities, free pizza, and attend a national conference. Send applications to [email protected]. @LoyolaCaMP @LoyolaHSC Supported by @AHAScience
Image from Jonathan Kirk (@jonathankirk)
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Congratulations to Taylor Phillips on her new paper! Membrane micropeptides interact with each other, altering their availability to regulate the calcium pump SERCA. AddThis | Home authors.elsevier.com/a/1gKoF…
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They’ve never looked so good
Image from Seth Robia (@SethRobia)
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Apparently my style is easy to emulate. And I do thumbs up a lot.
Image from Seth Robia (@SethRobia)
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Congrats to our dear John Yap who was just awarded the American Heart Association Pre-Doctoral Fellowship! We are SO proud of you, John!
Image from Loyola MD/PhD Program (@LoyolaMDPhD)
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Getting close! Apparently these phrases are things I say. But actually “Go make me famous” is a Dave Thomas quote. And “bald is beautiful” is said by everyone. Thanks Secret Santa (probably @JohnYap94299912 )
Image from Seth Robia (@SethRobia)
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My Secret Santa has been leaving me a few puzzle pieces at a time. Typical of my students to keep me in suspense, waiting for more data @JohnYap94299912 @JaroslavaNKA @jakedcunningham @SeeinClearly1
Image from Seth Robia (@SethRobia)
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