Countering deleterious phase transitions in ALS/FTD, PD, AD, and related disorders @Penn @PennMedicine @bb_upenn @BMBGGUPENN @PGGUPenn @PennNGG @CAMBUpenn
University of Pennsylvania
Joined January 2012
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ShorterLab retweeted
Sixers season opener is tonight. Every fan will get a white Sixers shirt #throwtheballup
ShorterLab retweeted
I'm obsessed with these empty clathrin cages people are seeing in neurons, and don't understand why others are not. So I put everything together and wrote a brief review (Current Opinion in Neurobiology, free access for 50 days):
sciencedirect.com/science/ar…
ShorterLab retweeted
SIXERS BEAT KNICKS 106-100 IN SEASON OPENER AT MSG
TYRESE MAXEY WITH 28 POINTS
JAYLEN BROWN WITH 19, LEBRON JAMES WITH 14, AND JOEL EMBIID WITH 13
#THROWTHEBALLUP
PLAY THE SONG
ShorterLab retweeted
City fit for a King👑
End of an era. The Phillies Daycare mural (last photo) on the side of Garage in Fishtown has come down and a new mural is being put up as we speak
I talked to the artist Liam who showed me what the new mural is going to be, and I think people will be excited about it. Should be done by the end of the week, progress pics to come🏀🌃
ShorterLab retweeted
Startup Acelot takes a swing at deadly, devastating Lou Gehrig's disease bizjournals.com/buffalo/bizw…
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Monomeric TDP-43 binds GU-rich RNA via its NTD but only its oligomers block cryptic exon inclusion biorxiv.org/content/10.64898…
ShorterLab retweeted
Engineered Chimeric Proteins Functionally Replace ALS-causing Endogenous FUS and TDP-43 to Improve Neuronal Health biorxiv.org/content/10.64898…
ShorterLab retweeted
The ALS community has lost one of its most powerful voices.
Brooke Eby was diagnosed with ALS in 2022 at just 33 years old. Instead of retreating, she made a choice that changed how the world sees this disease: she shared it all, with honesty and a sense of humor that made it impossible to look away.
She brought her employer Salesforce into the fight and raised more than $1 million for research. She helped build ALStogether so people with ALS could find one another. And she shared her story with the Today Show, The New York Times and People. In 2024, the ALS Association was proud to name her an ALS Hero.
"Brooke made ALS impossible to ignore, and she made it impossible not to love her while she did it," said ALS Association President and CEO Calaneet Balas.
Brooke died Thursday at 37. We will keep going until ALS is livable for everyone, and then cured.
Read our full statement: als.org/stories-news/brooke-…
