Insulin cells for type 1 diabetes got their blood supply weeks sooner. Karolinska researchers used an RNA switch so the cells call for blood vessels early, like ordering groceries before moving in. Human islets had blood flow in 12 days, not up to 42. sciencenews.dk/en/new-approa…
This week in stem cells:
○ The first patient given an iPS stem cell heart patch is recovering well.
○ 10 women with osteoporosis had 94% fewer broken bones after one stem cell drip.
○ Pruning unwanted cells made lab grown mini livers 3 times better at handling drugs.
Pruning makes better mini livers. Pitt scientists built SynBITE, a gene switch that tells unwanted cells in lab grown liver organoids to die, like a gardener clipping weak shoots. Drug processing jumped to 60% of real liver cells, up from about 20%.
medschool.pitt.edu/news/sele…
After one drip of their own stem cells, 10 women with advanced osteoporosis had 94% fewer broken bones in the next two years than in the two years before.
Source: Single Stem Cell Infusion Shows Promise in Advanced Osteoporosis, Suggests Study (Medical Dialogues) medicaldialogues.in/orthopae…
Up to 40% of mouse skin cells became neurons, up from about 3%, after UCLA scientists gave them a quick squeeze. Pushing cells through tiny channels loosens tightly packed DNA, like opening a stuffed suitcase so gene tools can reach what is inside. uclahealth.org/news/release/…
Brain building stem cells are easy targets for the COVID virus. UC Riverside found human neural stem cells let in safe lab copies of the virus, Omicron too. Blocking the cell's swallowing doorway cut entry by up to 85%. Next: test effects on brain growth.
news.ucr.edu/articles/2026/1…
Lab grown immune cells learned the local job in every organ. VIB scientists made early macrophage starter cells from human stem cells and put them in mice. They became microglia in the brain and matched the cleanup crews of the liver, heart and kidney.
press.vib.be/human-stem-cell…
Kids with severe heart defects often need surgery after surgery because their repair parts can't grow. Boston's new THUMPIN' project (up to $29.6M) aims to build living valves, vessels and patches that grow with a child, and one day a whole heart. seas.harvard.edu/news/boston…
Money from the world’s increasingly prosperous technology entrepreneurs has been flooding into biomedical research. Is it changing how science is done?
go.nature.com/4sfUkDV
The first patient to get RiHeart, a heart muscle patch grown from iPS stem cells, is recovering well. A week after surgery she could breathe deeper, and she goes home Oct 22. Think of it as a living bandage that helps a tired heart grow new blood vessels.
Patient recovering well after iPS heart sheet surgery in Japan english.kyodonews.net/articl…
Source: Patient recovering well after iPS heart sheet surgery in Japan (Kyodo News) english.kyodonews.net/articl…
Lab grown heart muscle clusters helped monkey hearts pump better 3 months after a heart attack. Next goal: make them from a patient's own blood cells, so no lifelong immune drugs.
Source: Human iPSC cardiomyocyte aggregate cell therapy in non human primates and correlation of heart recovery with contractile and electrophysiological cardiomyocyte properties (Nature Communications) nature.com/articles/s41467-0…
In 6 days, 7 chemicals turned about half of human stem cells in a dish into cells like those of an 8 cell embryo. Like rewinding a movie to its first scene, these cells can help build both body and placenta. The old way took 3 weeks (Cell Research). scienmag.com/seven-chemical-…
Old Blood Cells Have Been Transformed Into Brain Stem Cells That Get Younger As They Age
sciencealert.com/old-blood-c…
Stem cells by the back roads: Miami doctors got FDA clearance to send donor stem cells through the small arteries feeding painful arthritic knees, not just into the joint.
FDA Authorizes Novel Clinical Trial Exploring Artery Delivered Stem Cells for Knee Osteoarthritis news.med.miami.edu/artery-de…
Switching off one gene helped lab grown heart cells hide from the immune system. Japanese scientists turned off TAPBP in stem cells, so the heart cells show fewer ID tags. In lab tests, killer T cells attacked far less, and NK cells left them alone. doi.org/10.1016/j.isci.2026.…






