@Structure_CP

Structure is a monthly publication of @CellPressNews dedicated to research at the cutting edge of #structuralbiology. Tweets are by the Editors.

 Cambridge, MA, USA
cell.com/structure/home
Joined August 2012
  • Tweets8.6K
  • Following988
  • Followers6.9K
1KMedia
Online now! Structural analysis of de novo-designed binders targeting the closed state of HSP90 dlvr.​it/TVxXTq
1
2
8
581
Online now! Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region dlvr.​it/TVtQzB
2
10
672
A missing piece of the WFC trafficking complex revealed by cryo-EM dlvr.​it/TVnZd9
6
19
1,361
Q&A with Christopher O. Barnes dlvr.​it/TVnVYb
254
Meet the author: Nadia Izadi-Pruneyre dlvr.​it/TVnNmY
245
Structures of the human sodium-citrate cotransporter NaCT with and without substrates dlvr.​it/TVnDws
4
11
840
γ-glutamyl carboxylase inhibition by Anisindione dlvr.​it/TVljjk
2
4
23
1,342
Shared ligand-blocking mechanism but distinct conformational modulation by α5-targeting antibodies BIIG2 and MINT1526A dlvr.​it/TVlcnB
1
1
11
2,693
Structural plasticity drives convergent evolution and functional diversification of GNAT polyamine acetyltransferases dlvr.​it/TVlQCj
2
7
418
Structural determinants of endopilus assembly, stability, and functional specificity in bacterial type II secretion dlvr.​it/TVlGGQ
1
294
Morphotype-resolved 3D morphometry reveals a structure-density-location coupling in mitochondrial networks dlvr.​it/TVkrRd
2
285
Cryo-EM structure of the WDR11-FAM91A1-C17orf75 complex involved in retrograde trafficking dlvr.​it/TVkkm9
3
7
657
Conformational signatures of native ligand and pharmacochaperone binding in rhodopsin dlvr.​it/TVkfFm
1
6
18
1,157
Ligand-dependent interdomain rearrangements drive catalysis by acetyl-CoA synthetases dlvr.​it/TVkWWv
288
Online now! Virulence gene regulation in Pseudomonas aeruginosa is mediated by a novel hinge motion in the signaling helix of GacS histidine kinase dlvr.it/TVhvPM
2
5
551
Online now! Reconstructing hidden GPCR conformations and ligand binding modes through integrative DEER modeling dlvr.it/TVhn4w

Reconstructing hidden GPCR conformations and ligand binding modes through integrative DEER modeling

Belyaeva and Elgeti present an integrative modeling pipeline for proteins that combines experimental DEER data with deep-learning techniques and short molecular dynamics simulations. Application to...

cell.com
4
11
901
Online now! Chaperoning by dynamic encasement: Structural basis of linker histone H1 nuclear import dlvr.it/TVf4qn

Chaperoning by dynamic encasement: Structural basis of linker histone H1 nuclear import

Combining cryo-EM and molecular dynamics, Fu et al. show how two importins form an acidic cage around the extremely basic linker histone H1 for nuclear import. Rapidly exchanging contacts shield the...

cell.com
2
3
654
Online now! Structures of distinct human acetylcholinesterase tetramer forms in complex with synaptic anchoring proteins dlvr.it/TVbgWl
2
7
1,212
Online now! Molecular basis of metal transport by human ZnT10 dlvr.it/TVbY70
2
1
19
1,766
Online now! Cryo-electron tomography of functionally validated synapses in human induced neurons dlvr.it/TVY02m

Cryo-electron tomography of functionally validated synapses in human induced neurons

Houcek et al. investigated the function and structure of synapses formed between induced human neurons using electrophysiology and cryo-ET. They compared synapse function between iNs off and on EM...

cell.com
5
18
1,623
Load more