Antony Abraham (@antabra) header
Antony Abraham (@antabra) profile picture

Antony Abraham

@antabra

Neuroscience//Music

 North Carolina
Joined October 2008
  • Tweets768
  • Following4.1K
  • Followers1.4K
30Media
Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)Photo by Antony Abraham (@antabra)
Happy to share that I’ve started my lab in the Center for Drug Discovery at Research Triangle Institute (RTI) in North Carolina! Grateful to all the mentors, colleagues, friends, and family who have provided so much support and guidance along the way.
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mbruchas (@mbruchas) profile picture
mbruchas@mbruchas8 May 2025
Please chk out the lab's newest paper, a labor of love it was. From @aluskin & @dilithium21, w/ @madisonmartin @Braininajarr @mouse_braind @GoldenNeuron @gstuber & others. We report a new road map for the LC-NE & peri-LC systems. Thx @NIMHgov @NIDAnews nature.com/articles/s41586-0…
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David Marcus (@DavidJMarcus2) profile picture
David Marcus@DavidJMarcus210 Jan 2025
I’m excited to share the most recent study from the @mbruchas lab, which represents the culmination of my postdoctoral work, and serves as the platform for my future research programs investigating the in vivo role of the endocannabinoid signaling system! biorxiv.org/content/10.1101/…
Endocannabinoids facilitate transitory reward engagement through retrograde gain-control

Endocannabinoids facilitate transitory reward engagement through retrograde gain-control

Neuromodulatory signaling is poised to serve as a neural mechanism for gain control, acting as a crucial tuning factor to influence neuronal activity by dynamically shaping excitatory and inhibitory...

biorxiv.org
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Jibran Khokhar (@DrJKhokhar) profile picture
Jibran Khokhar@DrJKhokhar22 Oct 2024
Amazing new work by @KateNautiyal!
bioRxiv Neuroscience (@biorxiv_neursci) profile picturebioRxiv Neuroscience@biorxiv_neursci22 Oct 2024
The non-hallucinogenic serotonin 1B receptor is necessary for the antidepressant-like effects of psilocybin in mice biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Striatal Serotonin Release Signals Reward Value jneurosci.org/content/44/41/… Congrats to @KateNautiyal and team!! 👏👏

Striatal Serotonin Release Signals Reward Value

Serotonin modulates diverse phenotypes and functions including depressive, aggressive, impulsive, and feeding behaviors, all of which have reward-related components. To date, research has focused on...

jneurosci.org
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BryanRoth (@zenbrainest) profile picture
BryanRoth
@zenbrainest29 Sep 2024
Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits biorxiv.org/content/10.1101/…
Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

We present an enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits. Best-in-class vectors were curated for accessing major striatal neuron populations including medium...

biorxiv.org
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Dopamine D2/3 receptor densities may underlie the functional architecture of cocaine use. @AvramHolmes; @RicardJocelyn; @loic_lbc; @AshleaSegal; @elvisha9; @carrisa_cocuzza; @yip_lab; @SidChop doi.org/10.1038/s42003-024-0…
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Very proud to have my first first author paper published today in @npp_journal ! If you're interested in dopamine and cocaine incubation consider taking a look. nature.com/articles/s41386-0…
Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression...

Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression...

Neuropsychopharmacology - Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving

nature.com
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Congrats to our very own @TheErinCalipari on the Jacob P. Waletzky Award from @SfNtweets recognizing her work on addiction! Find out more about the award here: sfn.org/initiatives/awards/s…
Image from Vanderbilt Center For Addiction Research (@VCARScience)
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Niko Massaly (@MassalyNiko) profile picture
Niko Massaly@MassalyNiko17 Sep 2024
Our lab is looking for a motivated postdoc interested in dissecting the circuits of pain negative affect. More details about the lab here : massalylab.com/ & contact me here : massalylab.com/opportunities I will also be at #SfN24 in a couple of weeks to chat more.
Massaly Lab

Massaly Lab

massalylab.com
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Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability biorxiv.org/cgi/content/shor… #biorxiv_neursci
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We're thrilled to share the lab's first preprint- on CRF neurons, hypocretin/orexin signaling, and BNST neurophysiology in excess alcohol drinking and withdrawal-enhanced anxiety behavior! A collaborative effort with @JulieKauer75377 and @AnneVassalli, led by postdoc Dr. Yihe Ma
Image from Giardino Laboratory (@GiardinoLab)
bioRxiv Neuroscience (@biorxiv_neursci) profile picturebioRxiv Neuroscience@biorxiv_neursci8 Sep 2024
Sex-Specific Roles of Hypocretin Receptor Signaling in CRF Neurons on Alcohol Drinking, Anxiety, and BNST Neuronal Excitability biorxiv.org/cgi/content/shor… #biorxiv_neursci
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A dopamine-dependent mechanism for reward-induced modification of fear memories biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Antony Abraham retweeted
Tallie Z Baram (@z_baram) profile picture
Tallie Z Baram@z_baram3 Sep 2024
Just dropped- a really epic work from @sciencejuls and Larry Zweiffel, finally uncovering the functions of the enigmatic nucleus-accumbens CRH cells in reward behaviors. Unsurprisingly, this peptide's actions remain, ahem, WEIRD. sciencedirect.com/science/ar…
Image from Tallie Z Baram (@z_baram)
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BryanRoth (@zenbrainest) profile picture
BryanRoth
@zenbrainest22 Aug 2024
Position for computational chemist at RTI: nam12.safelinks.protection.o… Please RT
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Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit biorxiv.org/cgi/content/shor… #biorxiv_neursci
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New work out in @npp_journal from @CaitAnne @alexa_wheeler_ & team highlighting a potential role for D2Rs (but not D1Rs or D3Rs) sensitivity in the basolateral amygdala in contributing to sex differences in risk-based decision-making in🐀 nature.com/articles/s41386-0…
Image from Neuropsychopharmacology (@npp_journal)
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jneurosci.org/content/44/30/… Mixed selectivity…in the auditory midbrain? @GArtofscience certainly says so. Additional shout out to the reviewers who provided some of the most constructive and eloquently written critiques of my career thus far.
Mixed Representations of Sound and Action in the Auditory Midbrain

Mixed Representations of Sound and Action in the Auditory Midbrain

Linking sensory input and its consequences is a fundamental brain operation. During behavior, the neural activity of neocortical and limbic systems often reflects dynamic combinations of sensory and...

jneurosci.org
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Happy to have contributed to the development of novel endogenous opioid biosensors. Thank you @JasonCDong1 for being an amazing collaborator, @LinTianPhD for the opportunity, @mbruchas for the guidance and @NIDAnews for the funding!
Lin Tian, PhD (@LinTianPhD) profile pictureLin Tian, PhD@LinTianPhD15 Jul 2024
New paper out in @NatureNeuro! Collaborating with several labs, we developed genetically encoded biosensors to track opioid pharmacology in the brain & provide powerful new tools for dissecting complex circuit-specific dynamics 🔧🧠 nature.com/articles/s41593-0…
Image from Lin Tian, PhD (@LinTianPhD)
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Antony Abraham retweeted
Lin Tian, PhD (@LinTianPhD) profile picture
Lin Tian, PhD@LinTianPhD15 Jul 2024
New paper out in @NatureNeuro! Collaborating with several labs, we developed genetically encoded biosensors to track opioid pharmacology in the brain & provide powerful new tools for dissecting complex circuit-specific dynamics 🔧🧠 nature.com/articles/s41593-0…
Image from Lin Tian, PhD (@LinTianPhD)
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