Research Track Psychiatry Resident @StanfordMed | MD, PhD in Neurosciences @UCSD | Human Neurophysiology and Neuromodulation
Stanford
Joined December 2020
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In @PNASNews, we report the first recordings of human neurons during transcranial magnetic stimulation (TMS) of the prefrontal cortex, a treatment for depression. Until now, it was unknown how TMS affects neurons in deep brain regions that regulate mood. doi.org/10.1073/pnas.2610803…
These results show, at the level of individual neurons, how single pulses of TMS to the prefrontal cortex engage neurons in the deep brain networks that regulate mood. This is a fundamental step toward more effective TMS treatments for psychiatric and neurological disorders.
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I am deeply grateful to my mentors @DrCoreyKeller, Joel Berger, and @boeslab, and co-authors @neuro_engineer, Hiroto Kawasaki, Ariane Rhone, Christopher Cline, Nicholas Trapp, Matthew Howard, and the patients who participated. @PNTlabStanford @StanfordBrain @uiowa @UIowaNeuro
Outstanding work by @IlyaVerz that expands our understanding of how ripple oscillations in the human brain support memory!
Our new paper is out today in @NatureNeuro. We investigated how neural activity in physically distant brain regions coordinate during working memory, using human intracranial recordings. (1/5) 🧵👇
nature.com/articles/s41593-0…
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Charlie Dickey retweeted
New in @AmJPsychiatry — personally I think this is my best paper so far. Highest statistical rigor, strongest causal inference (via a series of natural experiments), and multiple clinical applications.
Thanks @KJBinSTL and team tagged below.
psychiatryonline.org/doi/10.…
Charlie Dickey retweeted
Our new paper is out in Brain Stimulation @brainstimj
"Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle"
With an amazing team @tobergmann, @ulfziemann1 @czrenner @ Prince Okyere & @ Milad Amini
brainstimjrnl.com/article/S1…
Charlie Dickey retweeted
1/10 We need better ways to measure brain excitability in psychiatric disorders. The prefrontal cortex—key target for brain stimulation treatments—is particularly hard to assess. Our new studies tackle this with systematic mapping! bit.ly/4cjHknX &bit.ly/3PW8RCx
Charlie Dickey retweeted
🚨 New preprint alert 🚨 Musical rhythms can boost brain stimulation effects! ⚡️ Sensory-entrained #TMS (seTMS) synchronizes TMS pulses with auditory rhythm-induced high-excitability brain states 🎶🧠
Thread below 👇 @StanfordMed @StanfordBrain (1/10)
1/5 Excited to share our new paper where we used a rare selection of direct recordings from the human thalamus to understand its role in coordinating high frequency oscillations, called ripples, in the cortex and hippocampus during sleep. plos.io/3UYXnkb
The #thalamus syncs spindles & Up states in cortex for memory, but what about co-ripples in #hippocampus & neocortex? @cdickey_ &co show that during human sleep, thalamic spindles & Up states sync networks that regulate #memory consolidation #PLOSBiology plos.io/3UYXnkb
4/5 These results show how the thalamus may orchestrate oscillations throughout the brain for memory consolidation during sleep.
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5/5 Thank you very much to everyone who helped move this research forward! @IlyaVerz
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4/5 These results show how the thalamus may orchestrate oscillations throughout the brain for memory consolidation during sleep.
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5/5 Thank you very much to everyone who helped move this research forward! @IlyaVerz
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