Charlie Dickey (@cdickey_) header
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Research Track Psychiatry Resident @StanfordMed | MD, PhD in Neurosciences @UCSD | Human Neurophysiology and Neuromodulation

Stanford
Joined December 2020
Photo by Charlie Dickey (@cdickey_)Photo by Charlie Dickey (@cdickey_)Photo by Charlie Dickey (@cdickey_)Photo by Charlie Dickey (@cdickey_)Photo by Charlie Dickey (@cdickey_)Photo by Charlie Dickey (@cdickey_)
New in @AmJPsychiatry — personally I think this is my best paper so far. Highest statistical rigor, strongest causal inference (via a series of natural experiments), and multiple clinical applications. Thanks @KJBinSTL and team tagged below. psychiatryonline.org/doi/10.…
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Our new paper is out in Brain Stimulation @brainstimj "Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle" With an amazing team @tobergmann, @ulfziemann1 @czrenner @ Prince Okyere & @ Milad Amini brainstimjrnl.com/article/S1…
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1/10 We need better ways to measure brain excitability in psychiatric disorders. The prefrontal cortex—key target for brain stimulation treatments—is particularly hard to assess. Our new studies tackle this with systematic mapping! bit.ly/4cjHknX &bit.ly/3PW8RCx
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🚨 New preprint alert 🚨 Musical rhythms can boost brain stimulation effects! ⚡️ Sensory-entrained #TMS (seTMS) synchronizes TMS pulses with auditory rhythm-induced high-excitability brain states 🎶🧠 Thread below 👇 @StanfordMed @StanfordBrain (1/10)
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Charlie Dickey retweeted
Want a tool that uses ML to generate REALLY good fake brain recordings? You're getting one. Julius' paper on diffusion models for brain data is published! Works with all kinds of densely sampled, multichannel continuous signals (LFP, EEG, etc.) cell.com/patterns/fulltext/S…
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Theta-burst stim (TBS) is used to treat depression, but how does it work? I dug into this question in my research yr with @DrCoreyKeller @ACPaulk, now out in @NatureComms, finding that TBS can produce plasticity-like changes in just minutes of stim. nature.com/articles/s41467-0…
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Charlie Dickey retweeted
We spent hundreds of hours recording neural activity from sleep and arousal-related cell types in the deep brain, all while delivering variant focused ultrasound pulsing schemes to gain insight into one of the most daunting questions in the field: 'What are the parameters?'.
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Ethan A. Solomon et al. found that TMS directed at the DLPFC resulted in iEEG low-frequency increases in frontolimbic cortices and high-frequency decreases in frontotemporal areas, including the hippocampus. More interesting findings can be found here: brainstimjrnl.com/article/S1…
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Delighted to announce our latest paper. We discovered single-cell correlate of theta-gamma PAC. Hippocampal PAC cells participate in control of WM through information-enhancing noise correlations and long-range frontal interactions. @Nature @CedarsSinai nature.com/articles/s41586-0…
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Stimulus-specific neurons activate together during hippocampal ripples when humans encode and retrieve associative memories @lks_kunz @neurojosh nature.com/articles/s41593-0…
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Our new study is out today in @Nature! We employed Neuropixels recordings to understand how speech is produced by single neurons in the human brain. nature.com/articles/s41586-0…
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Charlie Dickey retweeted
New paper online! In 2018, we found a human brain signal that tracks real time fluctuations in mood/anxiety. Now Adam Jackson back-translates this biomarker to mice, dissects its circuit mechanisms, & tests its causal relationship to emotional state. 🧵1/6 authors.elsevier.com/sd/arti…
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Charlie Dickey retweeted
New paper! We examined how ripples organize activity of neurons across a patch of human cortex during spontaneous behavior. Implications for neural binding, potentially across large distances. Big thanks to coauthors, @BrainGateTeam, and reviewers! pnas.org/doi/10.1073/pnas.23…
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Charlie Dickey retweeted
To treat OCD, Deep Brain Stimulation to the ventral capsule is effective – but the optimal target site remains unclear. In a huge collaborative effort @garance_meyer & @c_neudorfer set out to determine it @BiologicalPsyc1. A 🧵 👇👇 researchgate.net/publication…
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We’re excited about our first paper looking at speech encoding in single neurons across the depth of human cortex. Out today in @nature! nature.com/articles/s41586-0… [1/6]
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“Our ultimate goal is to understand the inner world of human beings, as it is experienced in health and disease.” – Karl Deisseroth, MD, PhD, the D. H. Chen Professor and a professor of bioengineering and of psychiatry and behavioral sciences med.stanford.edu/news/all-ne…
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Super proud of the team and our work demonstrating how real world network connectivity can be used to inform behavior. Cammie, @GraceNg_MD, Young-hoon, Rajat, Josh, @DaniSBassett, @halpernc @StanfordNsurg @PennNSG sciencedirect.com/science/ar…
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So happy to finally have my thesis work with the world. Our team asked how naturally occurring genetic variants in inbred strains of mice effect transcription and epigenetic regulation in vivo, using Kupffer cells as a model system nature.com/articles/s41590-0…
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Kudos to our amazing team for reaching this milestone in our #Depression #TRD #DBS work --integration of electrophysiology, behavior and imaging data leveraging neurotech/device advances and explainable AI. Next step: test the biomarkers in future patients. stay tuned.
Excited to share this paper using new neurotech and explainable AI to advance DBS for treatment resistant #depression (TRD). Team effort including @HelenMaybergMD, @sankar_alagapan and Patricio Riva-Posse. Summary thread! go.nature.com/48lmlzC @nature PC: Mike Halerz
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