🫀Vice Chair of Research (Surgery), Professor of Surgery & BME @ Columbia University
New York, USA
Joined May 2009
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Columbia scientists discover surprising link between serotonin and heart valve disease sciencedaily.com/releases/20… @lab_ferrari
In the tristate area? Discover what CT & vascular surgery trainees are working on! Join us at #CUMC on Oct 10 for our Regional Surgical Trainee Research Symposium. Learn from residents and fellows, share ideas, and make connections. Details below! @ColumbiaSurgery @ColumbiaCVRI
New work from our team, now accepted in Cardiovascular Research: a novel mechanotransduction pathway linking PIEZO1/2 to serotonin signaling in human mitral valve. These findings suggest new therapeutic targets to slow progression of degenerative MR. pubmed.ncbi.nlm.nih.gov/4268…
Giovanni Ferrari PhD retweeted
Congratulations to the 2026 Horwitz Prize honorees!
Columbia University will award the 2026 Louisa Gross Horwitz Prize to Adrian Bird and Huda Zoghbi for their pioneering work on epigenetic regulation in the nervous system and its role in human neurological disease, particularly Rett syndrome.
Read more: cuimc.columbia.edu/news/2026…
A short but very rewarding visit to #ESCCongress 2026 in Munich is soon coming to an end. Great science, inspiring conversations, and the opportunity to reconnect with colleagues from around the world. @Sugatrt well done @lab_ferrari
An unusual off-cycle opportunity has opened at Columbia/CUIMC: two NIH T32-funded postdoctoral research fellowship positions in Cardiac Surgery and Cardiovascular Science. We are looking to fill both ASAP @ColumbiaSurgery
This is an exceptional opportunity for MD/DO candidates committed to academic surgery, cardiovascular biology, translational medicine, biotechnology, and surgical innovation. Fellows will receive structured mentorship and academic training
Research areas include cardiac valve biology, biomaterials, implantable valve degeneration, biomedical engineering in heart transplantation, and extended cardiac preservation. NIH T32 eligibility requires U.S. citizenship or permanent residency.
Apply: [email protected]
🚨New: Pyriphenone-modified bovine pericardium mitigates AGE deposition, calcification, serum protein uptake, and platelet/WBC adhesion while preserving valve mechanics and hydrodynamics.
Relevance for #SAVR and #TAVR next-gen biomaterials
PMID: 42315002
pubmed.ncbi.nlm.nih.gov/4231…
New work with Dr Sacks shows that how we model the 3D matrix around cells can change what we think cells are doing. For mitral valve cells, better force measurements mean clearer insight into disease progression and therapeutic testing. sciencedirect.com/science/ar… @ColumbiaSurgery
Grateful to the 4 reviewers for their aligned yet mutually contradictory feedback. The manuscript is now simultaneously shorter, longer, clearer, and more comprehensive. Please find the revised version attached. P.S. I am equally complicit. Been one of them
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SERT inhibition and heart valve disease.
Serotonergic drugs (SSRIs/SNRIs) are associated with ~2.8x increased HVD risk. Mechanistically, altered serotonin signaling promotes valvular fibrosis and remodeling sciencedirect.com/science/ar…
Abstracts closing soon for the 20th Biennial @AppliedCVB Meeting (Miami, Nov 11–14)
Share your work in cardiovascular biology, biomaterials, regenerative medicine, valve disease, & transplantation.
Deadline: May 8, 2026 (11:59 PM ET) isacb.org/2026-biennial-meet…
Incredibly honored to be elected to the @AATSHQ. As a PhD in surgery for 20+ years, this reflects incredible collaborations with surgeon-scientists at @nyulangone @pennsurgery and most of all, my very own @ColumbiaSurgery @ColumbiaCTSurg the place that made everything possible 🫀
Fantastic keynote by Dr. Raza on cancer prevention and implantable intelligence. The era of biosensors is here: transforming how we detect, monitor, and intervene. Proud to be part of this evolving story #AATSHQ
The challenge of Heart and Liver Transplant in patients with adult Congenital Heart Disease. Dr Takeda @ColumbiaSurgery #CHD #ACHD #AATSHQ
We should always question what we do. TA-NRP in DCD heart transplantation is a clear example. The debate itself is a healthy driver of progress. How can biology help clarify what we mean by death? #AATSHQ
The great tradition of outstanding matches for @lab_ferrari PGY research members continues.Huge congratulations to Dr. Kosuri (MGH) and Dr. Levine (Cornell) on matching into exceptional fellowship programs. Strong science and persistence pay off @ColumbiaSurgRes @ColumbiaSurgery
