Associate Professor and Neuroscientist at McGill University https://xitter.gq/t.co/xjzOfSHwLN https://xitter.gq/t.co/DmMYVJkUCP
Montréal, Québec
Joined April 2017
- Tweets1.6K
- Following326
- Followers1.1K
- Likes2.2K
Mark Brandon, PhD. retweeted
In @PNASNews, we report the first recordings of human neurons during transcranial magnetic stimulation (TMS) of the prefrontal cortex, a treatment for depression. Until now, it was unknown how TMS affects neurons in deep brain regions that regulate mood. doi.org/10.1073/pnas.2610803…
Mark Brandon, PhD. retweeted
1/3 We built COMET (Cortex-wide Observational Miniature Epifluorescence Technique), a 3.75-g head-mounted mesoscope for cortex-wide, cellular-resolution calcium imaging in freely moving mice.
φ10-mm FOV, single-cell resolution.
biorxiv.org/content/10.64898…
#neuroscience #miniscope
Mark Brandon, PhD. retweeted
Large-scale neural activity data across wakefulness, sleep, and anesthesia are now open. Includes EEG/EMG, brain states, Ca²⁺ traces, and spikes. Please download and play with the data!
Cell Reports: doi.org/10.1016/j.celrep.202…
Scientific Data: doi.org/10.1038/s41597-026-0…
Mark Brandon, PhD. retweeted
Miniscope Zero, the first fully wireless Miniscope, is on @biorxivpreprint!
Wireless power + data enable neural recordings in enclosed mazes, 3D environments & from two animals at once! @BroschMarcel @MiniscopeTeam
Paper: doi.org/10.64898/2026.09.05.…
Wiki: miniscope.org/wiki/Miniscope…
Mark Brandon, PhD. retweeted
🎉 Congratulations to Zach Pennington on receiving this year's @BantingResearch Discovery Award!
I worked closely with Zach when he was a postdoc in my lab and I know he is incredibly deserving of this award.
Read more about his award here: psych.ubc.ca/news/zachary-pe…
Mark Brandon, PhD. retweeted
Not all neurons were created equal. Our marmoset cell type V1-LPFC resource is available and ready to serve the community. We used the same stimulation protocols as @AllenInstitute celltypes.brain-map.org/expe…, so the data can be compared to mice and humans
primatedatabase.com/ephysCT.…
Mark Brandon, PhD. retweeted
A partial list of speakers for our 2027 Gordon Conference on Entorhinal-Hippocampal Memory Circuit in California is up!
grc.org/entorhinal-hippocamp…
Speakers, please retweet!!
@brainrhythms @Serenadudette @pgolshani @Franklandlab @mazen_kheirbek @MacAskillAF @aa_fenton @LMPrida
Mark Brandon, PhD. retweeted
🌎 Check out the new GLOBE tool that uses protein tape recorders to measure single-cell activity on a brain-wide scale.
Congratulations to Changyang and team on developing and sharing this platform. Let us know what you think!
biorxiv.org/content/10.64898…
Introducing GLOBE—a new technology for brain-wide, single-cell recording of cellular activity in vivo. GLOBE can continuously record from nearly a quarter million individual neurons simultaneously across a mouse brain.
Preprint out on bioRxiv: doi.org/10.64898/2026.05.21.…
🧵(1/6)
ALT Recording scalability in vivo
Mark Brandon, PhD. retweeted
#MayThe4th be with you! Meet FORCE1s, a new positive‑going, ultrasensitive voltage indicator. Optimized for 2P imaging at slower acquisition speeds, FORCE1s is easy to use on almost any microscope. Bonus: it even powers 2P miniscope experiments!📄Preprint: biorxiv.org/content/10.64898…
Mark Brandon, PhD. retweeted
computational neuroscience has always known that real computation is spatial, temporal, and deeply non-linear. but for 30 years, simulating that reality meant relying on CPU-bound, non-differentiable tools. we built the engine to break that bottleneck.
Mark Brandon, PhD. retweeted
Sharing the latest from the lab. Led by Yunlong Liu, this work explores how microglia and engram neurons interact during fear extinction in the hippocampus.
rdcu.be/fgNH7
Mark Brandon, PhD. retweeted
🧵 Our new review is out in @AnnualReviews of Neuroscience. We examine path integration in Alzheimer’s disease and ask what early navigational changes can reveal about the underlying brain circuits.
Co-first-authored with Misun Kim and senior-authored by @NeilBurgess10
/1
Mark Brandon, PhD. retweeted
New preprint from our lab on 3‑photon microscopy with deep, fast, Ca-imaiging on a large field of view. It started with @a_negrean and @tgeiller and was led by an outstanding student, Tiberiu Mihaila, with major collaboration with
@DarcyPeterka.
biorxiv.org/content/10.64898…
Mark Brandon, PhD. retweeted
Functional neuromics in 3D... honored to be part of this team!
Excited about this project combining 2-photon imaging & spatial transcriptomics:
biorxiv.org/content/10.64898…
Lead scientist: @jason_hc_yong
Collaborator: @erdem___varol
Video: memorylongevity.org
Website: memorylongevity.org/merscope…
Mark Brandon, PhD. retweeted
Excited about this project combining 2-photon imaging & spatial transcriptomics:
biorxiv.org/content/10.64898…
Lead scientist: @jason_hc_yong
Collaborator: @erdem___varol
Video: memorylongevity.org
Website: memorylongevity.org/merscope…
Mark Brandon, PhD. retweeted
The Lippi lab is hiring a postdoctoral associate! We built new technologies to study post-transcriptional regulation in the healthy and diseased brain. We are recruiting motivated and talented scientists who will use these tools to discover new biology and new therapies.
Mark Brandon, PhD. retweeted
New paper out @NatureNeuro! Congrats to @EmilyAeryJones & team! The brain doesn’t just map where you are, it maps where it matters. Entorhinal cortex represents important, distant reward locations. A step toward understanding how experiences are linked across space.
rdcu.be/fbcS4
Mark Brandon, PhD. retweeted
add check out our work in M1. We also see this localized NA release, and the pattern of release actually changes with motor skill learning ;-)
biorxiv.org/content/10.1101/…
Wait… localized norepinephrine transients in the awake visual cortex?!
Who would have guessed this neuromodulatory signal is that spatially precise, right where visual processing is happening. Brain state control just got a lot more local. nature.com/articles/s41592-0…
Mark Brandon, PhD. retweeted
New preprint! Circuit wiring isn’t just anatomy, it shapes computation. Disrupting CA1→subiculum topography reorganizes spatial coding and destabilizes network dynamics. Great collab led by Yanjun Sun, & with D Pederick, X Xu & L Lou!
biorxiv.org/content/10.64898…
Mark Brandon, PhD. retweeted
The 3rd Neural Circuits and Behaviour satellite is happening May 18th at @CAN_ACN in beautiful Montreal. Registration is now open (link below).
eventbrite.ca/e/neural-circu…
