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$KURA KOMZIFTI® (ziftomenib) net product revenue grew 53% sequentially to $13.9 million; new patient starts increased 30% and total prescriptions grew 65% –
– KOMZIFTI maintained majority share of new patient starts of the menin inhibitor class in the R/R NPM1-mutated AML market –
– Eight abstracts accepted for ASH 2026, including two oral presentations on FLT3 inhibitor combinations, highlighting expanding development of ziftomenib in AML –
– FDA alignment for approximately 40-patient monotherapy registrational study of darlifarnib in HRAS-mutated salivary gland cancer; study initiation targeted for 1H 2027 –
– Darlifarnib combination studies in renal cell and pancreatic cancers expected to reach key development milestones in 2027 –
– Strong financial position, supported by $492.1 million in cash, cash equivalents and short-term investments, anticipated Kyowa Kirin collaboration payments and up to $300 million additional financing capacity from Oberland Capital –
– Management to host webcast and conference call today at 4:30 p.m. ET / 1:30 p.m. PT –
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The fact that China targeted Jensen underscores the geopolitical significance of AI leadership.
That means both Democrats and Republicans will need to build lots of data centers. $NVDA
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French students frantically search Christian Dior for school uniforms after their school reportedly ran out of blazers ahead of parents evening
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Brigitte Bardot, Sophia Loren, Claudia Cardinale, Catherine Deneuve e Ursula Andress.
Saint-Tropez, 1964
Readers added context they thought people might want to know
L'immagine non è una foto reale del 1964 ma un fotomontaggio generato dall'intelligenza artificiale.
x.com/DekaGuido/stat…
vogue.fr/lifestyle/trav…
leadstories.com/hoax-alert/202…
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Jonny Kim departed NASA today, August 27, 2026. After nearly ten years with the agency, the astronaut, naval aviator, doctor, and former SEAL is heading back to active duty as a Lieutenant Commander.
This is the close of one chapter and the start of another, and his impressive record still does most of the talking. He enlisted out of high school in 2002, trained as a hospital corpsman, made it through BUD/S, and joined SEAL Team 3. Across more than 100 combat operations he worked as medic, sniper, navigator, and point man in some of the war’s hardest years, coming home with a Silver Star and a Bronze Star with Combat V.
Then he went to Harvard Medical School and practiced as an emergency physician. NASA selected him in 2017. In 2025 he launched on Soyuz MS-27 for a 245-day expedition on the International Space Station, circling Earth 3,920 times and covering nearly 104 million miles. He became the first Korean-American to serve aboard the station.
Agency leadership did not undersell the sendoff. Administrator Jared Isaacman called him someone who represents the very best of NASA, a person who kept stretching the edge of exploration while inspiring a great many others.
The chief of the Astronaut Office pointed to the humility, precision, and steady commitment he brought to every assignment. Officers detailed from the fleet to NASA and then sent back to their parent service is an established path. Kim is the latest to take it: from orbit back to Navy blue.
SEAL, doctor, astronaut, and now full time Navy again. Whatever follows is unlikely to be quiet.
Respect 🔱
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I'm looking at a summary of an analyst report on Salesforce's numbers last night (20% stock target price upgrade, of course) and I see this explanation: "NNAOV growth was the strongest in four years and significantly outpaced AOV growth, attrition was near record lows, contract duration improved across both new business and renewals, and CRPO accelerated to 14% constant currency, a point ahead of guidance"
NNAOV, AOV and CRPO?? Whatever happened to sales & earnings and balance sheet changes? Oh yeah - they don't look so good. Salesforce revenues (+10.8% Y/Y - includes price hikes/inflation). Income from operations (DOWN slightly year-over-year - the big gain in EPS was entirely due to " $2.6 billion of "gains on strategic investments." And the balance sheet: A total wreck. YTD, Debt nearly quadrupled to $39B, total assets declined, total liabilities jumped 34% and stockholders' equity plummeted 35%. I can hear the analysts' refrain on the conference call now: "Nice quarter guys!"
Come See Us!
The Humacyte team will be at leading vascular and surgical meetings across North America, sharing the science behind Symvess and offering hands-on opportunities to handle, cut, and suture the vessel.
From exhibit booths to simulation stations and symposium sessions, each meeting offers an opportunity to connect with our team, ask questions, and explore how Symvess may help in extremity arterial injury when autologous vein graft is not feasible.
We look forward to connecting with you at the following meetings:
Alabama Vascular Society
Braselton, GA | Jul 30 – Aug 1
· Experience our Simulation Station
· Join us for our Breakfast Symposium with Miguel Manzur, MD — Friday, July 31 at 7:00 AM, Elan Ballroom D
Virginia Vascular Society Annual Meeting
Irvington, VA | Sep 11 – 13
AAST 85th Annual Meeting & Clinical Congress
Dallas, TX | Sep 16 – 19
Eastern Vascular Society Annual Meeting
Washington, DC | Sep 17 – 19
· Experience our Simulation Station
· Join us for a Technology Forum presentation
Midwestern Vascular Society 50th Annual Meeting
Chicago, IL | Sep 17 – 20
· Visit our Hands-On Station at the Technology & Technique Vascular Simulation Program on Thursday, September 17
Georgia Vascular Society Scientific Sessions
Greensboro, GA | Sep 18 – 20
Western Vascular Society Annual Meeting
British Columbia, CA | Sep 26 – 29
· Join us for a Lunch Symposium on Monday, September 28
Stop by, connect with our team, and see Symvess in action.
Learn more here: symvess.com.
PLEASE SEE IMPORTANT SAFETY INFORMATION INCLUDING THE BOXED WARNING, AND FULL PRESCRIBING INFORMATION at bit.ly/4dl5tuL
INDICATION
SYMVESS is an acellular tissue engineered vessel indicated for use in adults as a vascular conduit for extremity arterial injury when urgent revascularization is needed to avoid imminent limb loss, and autologous vein graft is not feasible.
GRAFT FAILURE: loss of SYMVESS integrity due to mid-graft rupture or anastomotic failure can result in life-threatening hemorrhage.
DO NOT use SYMVESS in patients who have a medical condition that would preclude long-term antiplatelet therapy after acute injury resolution.
WARNINGS AND PRECAUTIONS: Vascular Graft Rupture, Anastomotic Failure, and Thrombosis have occurred in patients treated with SYMVESS. SYMVESS is manufactured using cells and reagents that may transmit infectious diseases or agents; none have been reported during clinical testing.
ADVERSE REACTIONS: most common (≥3%): thrombosis, fever, pain, anastomotic stenosis, rupture or anastomotic failure, and infection.
Trademarks are the property of Humacyte Global, Inc.
© 2026 Humacyte Global, Inc. All Rights Reserved. US-SYM-000357
#Symvess #VascularSurgery #TraumaSurgery #LimbSalvage #SurgicalEducation #MedicalInnovation #BioengineeredVessel $HUMA
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En 1979, un presentador de TV le preguntó a Milton Friedman si no le daba vergüenza defender un sistema basado en la codicia.
La respuesta se estudia hasta hoy:
«—Cuando ves la mala distribución de la riqueza, tan pocos que tienen tanto y tantos que no tienen nada… ¿nunca has dudado del capitalismo, de si la codicia es una buena idea?
—Primero dime: ¿conoces alguna sociedad que NO funcione con codicia? ¿Crees que Rusia no funciona con codicia? ¿Que China no?
¿Y qué es la codicia? Ninguno de nosotros es codicioso, claro. El codicioso siempre es el otro.
Los grandes logros de la civilización no salieron de despachos del gobierno. Einstein no construyó su teoría por orden de un burócrata. Ford no revolucionó el automóvil así.
Los únicos casos en la historia en los que las masas escaparon de la pobreza son aquellos donde hubo capitalismo y libre comercio.
—Pero parece premiar la habilidad de manipular el sistema, no la virtud.
—¿Y qué premia la virtud? ¿Crees que un comisario comunista premia la virtud? ¿Un Hitler? ¿Crees que los presidentes americanos eligen sus cargos por virtud… o por peso político?
Dime: ¿dónde están esos ángeles que van a organizar la sociedad por nosotros?
Yo ni siquiera confío en ti para hacerlo.»
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Popular far-left French politician Louis Boyard discreetly took off his Rolex worth $50,000 before giving an interview ‘denouncing the ultra-rich.’
Hypocrisy at its finest.
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After receiving a serious diagnosis, one patient turned to several medical institutions in search of answers. Where other institutions saw limitations, Mayo Clinic's interdisciplinary team saw a way forward.
Learn more: mayocl.in/4f92RDL
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Important points from Apollo's Torsten Slok:
"Net foreign inflows into US equities have surged to a record high, driven in large part by overseas investors seeking AI exposure"
"With most foreign equity investors not hedging their FX risk, the bottom line is that if AI disappoints, the resulting pullback in these inflows would be a significant downside risk to the US dollar."
My take: It's not IF AI disappoints, the only question is when. And when that happens, the massively overbought dollar (hedge funds are also heavily long currently) could decline significantly and that would be an important propellant for gold (which is oversold and under-owned by hedge funds). Gold is currently signaling it may have already reached a bottom.
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$TMDX expanding the donor pool across the globe.
📍 Bergamo, Italy 🇮🇹
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BREAKING NEWS! Erdogan was prepared to join forces with Iran against our country and Israel?
The president has mentioned several times that he talked Erdogan out of entering the war on the side of the Iranian regime -- meaning, he talked Erdogan out of going to war with us and Israel? I really think that this needs to be explained in detail and fully pursued. If a NATO country was going to join the enemy in our war against Iran, we need to know all about it. The president is rightly condemning the lack of support from NATO countries, but in the case of Turkey, it was prepared to fight us? Can you imagine Erdogan using our military equipment against us? Now this thug will have our F-35s? And we're praising the hell out of this guy like he's our best friend? We need to know a lot more about this.
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A new chapter for #FocalTherapy at @ImperialNHS 🎯
@imperialurology is proud to introduce @FocalOneHIFU robotic HIFU into NHS clinical practice, expanding precision treatment options for men with prostate cancer 🚀💫
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What a weekend! ⚽️
Also… huge honour to lead my first Focal One Robotic HIFU list!
@ImperialNHS @IP_London
Indebted to:
@LondonProstate1 @TaimurShah
@FocalOneHIFU @joshuarobotics
Dr Pierre Charles Henry (HIFU Proctor)
Dr Markovic (Anaesthetist)
Anmol & Alfin
Onwards & upwards. Delighted to add this fantastic focal therapy option to the armamentarium. Excellent user interface & image integration.
#HIFU #FocalTherapy #July4th #QuaterFinals – at Hammersmith, London
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Hi @BernieSanders, your silence is deafening
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Don’t forget that last time Graham Platner was accused of mistreating women, not only did Ro Khanna defend him, he flew out to Maine to campaign for him.
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A big milestone for Rio Grande Valley👏
DHR Health has successfully completed its first RNS System implant, bringing advanced, responsive neurostimulation therapy to the Rio Grande Valley, an area where expanded access to specialized epilepsy care can truly make a difference.
Congratulations to the neurosurgical team and medical leadership led by Dr. Juan Torres-Reveron and Dr. Leonel Estofan on this important achievement. We’re proud to partner with you in helping patients with drug-resistant epilepsy.
#Epilepsy #RNSSystem #NeuroPace #ResponsiveNeurostimulation #MedicalMilestone #EpilepsyCare #Innovation
Safety info: neuropace.com/safety

































