
Staff š @MixMax - Author of "Serverless Applications with Node.js" @JSBelgrade & @MapMeetup co-organizer #WardleyMaps. AWS Serverless Hero, ex @Stedi
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Joined December 2010
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Super happy to announce that, we, the three Serverless musketeers (@gojkoadzic, @slobodan_ and me), are writing a new book āReal-time GraphQL applications with AppSyncā :)
so, apparently this is happening :) serverless.pub/running-serveā¦
One person biotech company acquired
āProphesiedā 8 years ago @swardley
Here
xitter.cf/swardley/status/106646ā¦
Surprise 1: Anthropic acquired a one-person biotech
.
.
.
Surprise 2: that person is me
Surprise 3: Iām here to tell you all about it
Yes, this is what you think it is; after 6 yrs of increasingly loose anonymity: the Professor Oak reveal post
ā¦and yes, it has gotten so boring around here that Iām literally doxxing myself to spice up the timeline
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Ok, allow me to introduce myself. My name is Cody Tranbarger. I mostly tweet, but occasionally find time to dabble in drug dev & starting/building biotechs. My past lives span the VC, crossover, startup continuum; Prof Oak has been my way of keeping a digital foot in those worlds, despite having my physical feet planted elsewhere.
The past 18 mo, āelsewhereā was Mithril Medicine, a co. I founded to develop bsAbs for LAMA2-CMD & other ECM-related genetic diseases.
Mithril was born out of hands-on building with @MikeNGladstone, @JasonPaulRhodes, @LifeSciVC, & team @atlasventure. Somehow, I made enough half-decent calls along the way (even a broken clock is right twice a day, eh?) to convince them Mithril/I warranted a small seed. While I can hardly rationalize such an outrageously cavalier bet, Iām grateful for it, & I'd partner with Atlas again in a heartbeat.
In typical AV fashion, Mithrilās primordial form was virtual, decentralized, & ultra-lean. This stage tends to be short-lived, but for Mithril, it worked surprisingly well, for surprisingly long, thanks in part to the rapid maturation of the AI tools I used liberally.
Eventually, Mithril became a bit of an experiment itself - to find the upper bound of how far it could scale as a single operator + a bunch of Claude (+ a stellar bench of part-time consultants).
In parallel, I started spending time with @nc_frey, @an1lam, & @CoefficientBio team; and promptly experienced, for the 1st time, AI at the frontier. Soon thereafter, Mithril stopped looking like an experiment, & started looking like a preview of an entirely new operating model.
From that spark came āPipeline-in-a-Person.ā The idea immediately resonated when we shared it here back in April; and it was central to the shared vision that led to Anthropicās acquisition of Mithril, & my joining the team.
Why join Anthropic? Three reasons.
(1) For Mithril, the programs continue, with more resources & infrastructure behind them, and as much Claude as I can put to work.
(2) For me, the chance to start several more programs, & find out how many one person can actually run in parallel - an almost unprecedented luxury for a curious drug hunter.
(3) For our mission, a path to institutionalize & scale this new way of working, then put it in the hands of all of biopharma, all over the world - which, candidly, I find the most energizing.
Will AI x Bio cure diseases? Unequivocally yes, imo⦠but not by the route that gets the most airtime. Rather than timeline acceleration & compression, I see orchestration & parallelization as today's low-hanging fruit.
Most drug hunters see a handful of go/no-go calls in a career, & spend entirely too much of the rest trading emails (my inbox can attest).
Give them the bandwidth to run several programs at once, and the time to focus on scientific judgment, and Iām willing to bet theyāll make better calls. And at scale, better calls translate to more drugs, higher hit rates, broader patient impact, & likely, a disease or 10 or 100 cured. I couldn't be more excited to build toward that future @AnthropicAI.
Finally, a heartfelt thank you to BioTwitter/X. The end of anonymity is bittersweet, but if anyoneās earned a proper introduction, you all have.
Itās difficult to overstate how much this app has done for me: a decade of education, plenty of friends, many job opportunities, several mentors, a few investors, even a co-founder (fmr). It was the generosity of this community that inspired me to start posting 6 years ago, after just as many years lurking. I hope Iāve been able to pay it forward, in my own small way.
But, to be clear, Prof Oak isnāt going anywhere. Same beat, same themes, and now, a front-row seat to drug development at the frontier. Stay tuned for dispatches from the trenches; and remember...
Gotta Cure 'Em All
Aleksandar Simovic retweeted
My fav presentation from AWS Community day Adria. Live demo with voice agent that worked perfectly well. @simalexan @siaterliskonsta
We put a voice agent on stage and let it listen to the whole room.
It knew who was speaking, designed the architecture with us, drew it, and flagged the risks
named it Ultron.
@siaterliskonsta and I talked about it at AWS Community Days Adria
Slides:
simalexan.com/presentations/ā¦
We put a voice agent on stage and let it listen to the whole room.
It knew who was speaking, designed the architecture with us, drew it, and flagged the risks
named it Ultron.
@siaterliskonsta and I talked about it at AWS Community Days Adria
Slides:
simalexan.com/presentations/ā¦
Aleksandar Simovic retweeted
Technical moats are mostly over at this point. If youāre building something that is meant to be durable, the only moats now are:
⢠Proprietary data
⢠Network effects
⢠A physical component
As @swardley predicted⦠SpimeScript
After six years in stealth, Atomic Machines is out. Our mission: on-demand, universal command of matter. First beachhead: the Matter Compiler, an AI-native manufacturing system that builds working micro-machines from code alone. No per-product tooling. No process development. Different code, different machine.
Aleksandar Simovic retweeted
Users now discover products through AI agents. Our apps need to evolve so that AI agents can sign up and show our product's value before a human visits. This looks like a natural PLG extension: provide value fast, then let an agent sell the "Aha!" moment.
Aleksandar Simovic retweeted
I built a @cursor_ai client that runs inside World of Warcraft as an addon so I can keep an eye on my agents and prompt them when i need.
Aleksandar Simovic retweeted
BIG ANNOUNCEMENT FROM HUGGING FACE TODAY:
We're unveiling Microduck š„š¤
It's a tiny $399 open-source robot you can teach new tricks with reinforcement learning. It can walk, pick things up, get back up when it falls, and even roller-skate.
Welcome to the era of open-source affordable robots to democratize physical AI and world models!
š¤š¤š¤
Aleksandar Simovic retweeted
What can Competitor Tracker do? Let me show you!
We watch more than 2,000 companies (and adding more daily; the goal is to have 5,000+ in a few weeks). The weekend crawl discovered 4,333 changes (1,920 are high-priority ones), peaking at 656 page changes in one hour.
We crawl hardest on weekends, sites are quieter, snapshots are cleaner. However, the market doesn't take weekends off. We know that because we caught Runway mid-migration to cfo_ai.
Here are the 5 most interesting changes we caught this weekend:
1ļøā£ G-P put a public price on enterprise EOR: $599/employee/month, one plan. And they weren't alone: CoAd, OnTheClock, and Employment Hero all published payroll pricing in the same sweep. The EOR/payroll space went price-transparent in one week. šŖ§
2ļøā£ Relay_app announced it's shutting down. Free users lose access on Aug 15, paying customers on Sep 14. An AI workflow automation player leaving the field. ā ļø
3ļøā£ Cloudchipr, the cloud cost-optimization tool, optimized the cost by doubling its own price. The Pro plan went from $445 ā $890/mo. šø
4ļøā£ Okta shipped agent-to-agent connections, GA. Agents can now securely call other agents under admin policy. The identity layer for the agent economy is being poured right now. š¤
5ļøā£ Runway, caught mid-migration to cfo_ai. The login, docs, and sales domains had already been moved. Websites often talk before the press release.Ā The migration now seems to be finished. šµļø
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You can try Competitor Tracker for free. The first 25 coins šŖ are on the house and cover 5 competitors for 5 months (1 coin tracks 1 competitor for 1 month).
Signing up and setting up the system takes just a few minutes. š competitortracker.io
š¤ Made with AI
Aleksandar Simovic retweeted
Building an AI demo is easy. Building a full product is still hard and takes weeks or months (luckily not years anymore).
@lavcrnobrnja and I built our new product Competitor Tracker with a pack of AI agents (mostly hands-off, but never unsupervised).
Here's the origin story (with the architecture, workflows, what didn't work, etc.):
slobodan.me/posts/introducinā¦
Aleksandar Simovic retweeted
A while ago, @lavcrnobrnja and I started building a small prototype: an app that tracks your competitors and emails you the most important changes every Monday. With help from a few people, it started working about a year ago. Early users liked it, so we turned it into a product.
While building and testing it, we began tracking changes across many industries, and the initial results are quite interesting. Itās been clear for a while that B2B is embracing AI. Now we have some numbers.
Hereās a snapshot across 20 selected industries (754 tracked products, charts below):
š 1 in 4 products added or at least mentioned an MCP, an AI agent, or both in the last 3 months.
š Customer Support, Workflow Automation, Sales Engagement, and AI Meeting Notes are clearly leading. HR-related industries are still lagging, though a few are starting to move.
š¤ MCP has been around for a while, but agents seem to be overtaking it now, running ~2x ahead this quarter.
Adoption is uneven but accelerating, and AI integrations are shifting quickly from a competitive advantage to a baseline expectation.
šø There are early signs that pricing is following the agent trend, with credits and usage-based models.
ā ļø Some companies are doubling down on AI and quietly dropping other verticals or product lines. Too early to call it a trend, but itās worth watching.
Aleksandar Simovic retweeted
We were very early huh @simalexan
We want to hook it up to our conversational programming system on top of the AWS serverless ecosystem. Sent requests through the form, I will shoot you an email. Here is an early demo youtu.be/XMrtHQ6ohcg
Aleksandar Simovic retweeted
I built a Claude Code notification system that uses Warcraft III Peon voice lines.
It's probably the stupidest thing I've ever shipped. And according to everybody that has used it, it's also incredibly useful.
(sound on)
Aleksandar Simovic retweeted
Cowork but with local models not to send all your data to a remote cloud!
Replying to @claudeai
In Cowork, you give Claude access to a folder on your computer. Claude can then read, edit, or create files in that folder.
Try it to create a spreadsheet from a pile of screenshots, or produce a first draft from scattered notes.
Aleksandar Simovic retweeted
AWS Meetup Belgrade Dec 25 5:30 PM- join us at our in-person event at the end of this year. We will review the latest releases from AWS straight from Las Vegas re:invent that has just finished. It will be a friendly, open discussion on what's cool, what is boring and general direction AWS is going. Organizing this event for you: @simalexan @extraequal and @goranopacic meetup.com/awsugbelgrade/eveā¦
Aleksandar Simovic retweeted
This year's Now Go Build Award goes to Raphael Quisumbing @RaphaelFra20009āa true "renaissance developer." He builds communities, mentors others, and translates tech into real solutions. Kudos to all 265 AWS Heroes across 58 countries leading the way. Now, go build!
Aleksandar Simovic retweeted
After almost 11 years, it's time for a new organization team to take over the @JSBelgrade meetup.
The journey started in December 2014, when @ispijac_kafe and I decided to organize our first JavaScript meetup and start the first (as far as I know) JavaScript meetup group in Belgrade. Even in the first meetup, we met some awesome people who quickly became friends, including @simalexan (who also became our coorganizer), @dejan_dimic, and several others.
Everything went smoothly until covid. We had many monthly meetups (with amazing speakers, the list would be too long), countless Coffeejs meetups, and some great free workshops. We met many awesome people. And, I personally learned a lot! However, after covid, many things changed, and with our limited free time, the meetup was no longer a priority. We organized a few events, just to keep it alive.
And then, last year, @simalexan and I met Ilija. He just started the Belgradejs meetup group, and we recognized the enthusiasm and passion we had when we started the JS Belgrade meetup. In the next year and a half, Ilija and his coorganizers, Sanel and Nikola, organized many other great events. We even organized one together in April. Finally, a few months ago, @simalexan and I sat down with Ilija, Sanel, and Nikola and agreed to merge our meetup groups. They'll continue as the main JS Belgrade organizers, and we'll help with everything we can.
I hope this marks the start of the next 10 years of JS Belgrade meetup, with many, many more events, workshops, and amazing people, of course.
Btw, join us on Thursday to meet the new organizing team: meetup.com/js-belgrade-meetuā¦
Also, if you want to speak at one of our future meetups, let us know!
Last week I enabled @kirodotdev AI Steering to help with build vs buy decisions and use Wardley Maps principles when building products
Showed a few gaps and how rules/steering evolution can potentially help with scaling principles across an organization
simalexan.com/posts/wardley-ā¦
























