Yuling Chow (@yulingchow) profile picture

Eats shoots and leaves, not necessarily in that order || Filmmaker/DP/Videographer from Hong Kong || Appalled by our response to Covid-19 & climate change

Joined June 2011
Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)Photo by Yuling Chow (@yulingchow)
👏👏Sjogrens is a serious multisystem disease not a mild dryness Syndrome It doesn’t start with sicca and “progress”to systemic. Time for better data. Dump the dogma!
"El síndrome seco es lo menos Sjogrenesco de la enfermedad de Sjogren" 🥹🥹 Años esperando las autoridades lo reconocieran Hasta el 70% de los pacientes jovenes con Sjogren no tendran sindrome seco y el sx seco es muy comun en pacientes SANOS de mayor edad.
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Yuling Chow retweeted
Air purifiers are a critical tool. You can’t, however, remove an N95 mask from the equation when other people are present even with complete air exchange cycles. Proximity (someone infected and breathing or talking right by you) is a risk only knocked down with a respirator mask.
With an N95 mask, at least 95% of the viruses and bacteria in every breath you take are filtered out. With an air purifier, it takes three air changes for 95% of the viruses and bacteria to be filtered out. The advantage of an N95 mask is that you don’t have to wait for three air changes, and it can block droplets, which an air purifier cannot do directly. Of course, you don’t have to choose one or the other—you can use both at the same time.
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Two mild COVID infections may weaken brains vulnerable to Alzheimer's, a study suggests In mice, repeated infections reduced neuron connections in memory-related brain regions and increased amyloid plaques, raising concerns about cumulative effects. Inflammation may play a role.
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Yuling Chow retweeted
Mice got a mild covid infection that never reached the brain. No inflammation, no neuron loss. Every check you'd run came back clean. Two weeks on - fewer synapses in the memory region, more amyloid. The protein that builds up in Alzheimer's🧵
Recurrent mild SARS-CoV-2 infection affects the lung-brain axis in wild type and Alzheimer’s mice 🚨New mouse study: two mild COVID infections (ancestral then Omicron) quietly damage hippocampal synapses and worsen amyloid plaques in Alzheimer’s models, no brain virus, no microglial activation. Lung–brain axis in action! 🚨Interesting BELGIUM study, that sparked broad MSM coverage, and that’s unique!🤔 ➡️“Even mild corona infections can leave traces in the brain: Ghent researchers discover possible link with Alzheimer's" ➡️Let’s dig into the study: - Mice received sequential mild intranasal infections: ancestral SARS-CoV-2 (10 PFU) followed 14 days later by Omicron BA.1 (7000 PFU), - Lungs showed detectable virus after each exposure, no viral RNA was found in brain (cortex/hippocampus) at the final time point (day 28), - Disease remained sublethal with low systemic/brain cytokine responses, - Two weeks after the second infection, microglia (IBA1) and astrocytes (GFAP) showed no significant changes in number, density, or reactivity in hippocampus or cortex of either genotype, - Hippocampal synaptic integrity was reduced (lower SYP+ presynaptic and SYP/PSD-95 colocalized puncta), most clearly in the Alzheimer’s disease model mice(AD mice), no neuronal loss (NeuN) was observed, - In AD mice only, repeated infection increased hippocampal Aβ plaque number (with area trend) and cortical insoluble Aβ1-40/1-42 levels. Soluble Aβ and microglial plaque association/phagocytosis were largely unchanged, - Effects appear mediated indirectly via the lung–brain axis rather than direct CNS infection. ➡️Attention: THIS STUDY IS EXPLICITLY A REINFECTION MODEL! ‼️So, even mild, repeated SARS-CoV-2 infections leave a measurable footprint on the brain, eroding hippocampal synapses and accelerating amyloid pathology in susceptible hosts, without triggering detectable neuroinflammation. And indeed, this study adds further experimental support to the idea that repeated SARSCOV2 exposures can produce lasting, subtle CNS effects relevant to longC0VID “brain fog,” cognitive complaints, and possible accelerated neurodegenerative risk. The absence of overt gliosis suggests the damage can be stealthy and cumulative rather than driven by classic neuroinflammation. For people with genetic or early Alzheimer’s risk, or those experiencing successive infections, the findings underscore the value of monitoring cognitive trajectories and considering cumulative viral burden as a potential modifier of brain health. It does not yet prove causation in humans but strengthens without any doubt the biological rationale for taking mild reinfections seriously! #AvoidSars2 #AvoidReinfections link.springer.com/article/10… hln.be/gent/zelfs-milde-coro…
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Yuling Chow retweeted
The Lyme Playbook, applied to Covid.
Imagine your job was to make the public doubt Long COVID. You wouldn't try to prove it isn't real. You'd just make it look unsettled, forever. That's the playbook that kept tobacco and climate science "debatable" for decades. Here's what it would look like applied to Long COVID:
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Yuling Chow retweeted
BioVie presented new findings from our Phase 2 ADDRESS-LC trial that suggest two distinct biomarker-defined #LongCOVID endotypes are associated with different patient responses to bezisterim treatment. See details about our presentation at the @FNIH_Org @NIH RECOVER-TLC workshop here: investors.bioviepharma.com/n… #LongCOVID $BIVI
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コロナ後遺症患者46人を対象としたJAK阻害薬「アブロシチニブ」の第2a相試験で、12週間の投与により疲労スコアが大幅に改善。炎症やT細胞の免疫疲弊に関連する経路も減少した。慢性炎症と免疫疲弊の関与を示唆する結果だが、小規模試験であり、今後さらなる検証が必要。 thesicktimes.org/2026/11/04/…
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Yuling Chow retweeted
New Zealand researchers followed 843 children over 5 years and found RSV caused more respiratory illness than COVID-19 or flu. Flu vaccination was associated with a 34% lower risk of illness. Age shaped flu and RSV risk, but not COVID-19. journals.asm.org/doi/10.1128…
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Yuling Chow retweeted
COVID-19 and dementia: Could the neurological impact last for years? ➡️ A massive UK study involving 18.3 million adults, followed for up to 5.5 years, found: Diagnoses of cognitive impairment and dementia increased sharply during the first month after COVID-19. ➡️ The increased incidence persisted for up to 4 years, particularly among patients hospitalised with COVID-19. Unvaccinated individuals showed a greater increase in risk than vaccinated individuals. 1/
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Yuling Chow retweeted
Public Health Wales researchers studied 410 communities in Wales and 120 Kentucky counties. Former coal mining regions had higher COVID-19 infections and deaths, even after accounting for poverty, age, and chronic illness. sciencedirect.com/science/ar…
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“Cattle movement consistently explained interstate viral spread more strongly than geographic proximity” — Discussion, p. 18 “we found no evidence that wild birds contributed to the geographic spread of B3.13 among dairy cattle.” — Discussion, p. 18 “each week of delay in policy implementation was associated with an additional median 11–12 infected counties per week” — Counterfactual simulations, PDF p. 16 “Real-time effluent or wastewater monitoring could reduce detection times further still, potentially to days rather than weeks or months.” — Discussion, p. 20.
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Yuling Chow retweeted
I’ve tried brain retraining, somatics, visualization, meditation, and every mind-body trick out of sheer desperation to recover from ME / long covid. Hands down some of the most useless things I’ve ever tried. Zero improvement in my functionality. If you claim you cured your mecfs by retraining your brain, forgive me for questioning that narrative. Some of us are dealing with a debilitating physiological illness, not a mindset problem.
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Yuling Chow retweeted
COVID does that. 2 of my doctors in their 40s have had strokes shortly after COVID infections. They're both practicing, but have different ways of dealing with the reality of a dangerous virus: One became a denier, and the other treats Long Covid.
News that U.S. Sen. Chris Murphy suffered a stroke was jolting in part because of his age: 53. Stroke rates are generally higher among older adults, but the data shows they’ve been rising among people younger than 55. (via @PolitiFact) to.pbs.org/3UDyq0M
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Yuling Chow retweeted
There's just zero good research on MCAS. There exist no *validated* diagnostic criteria at all. You cannot study a condition if you can't tell who has it. Hard to beat ME/CFS at being neglected but they've managed to do it to MCAS. (I don't have MCAS)
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No one who judges you for wearing a respirator will be there for you if you find yourself chronically ill or Disabled. #MaskUp
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Yuling Chow retweeted
Adverts on the telly for monitoring your new onset atrial fibrillation, but no adverts on the telly telling you how to avoid the virus that gives you atrial fibrillation. If my eyes rolled any harder I'd bore a hole into the earth.
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PJ.2.1 • First detected in Canada in May 2026 • Spreading across the US, Europe and Asia • Symptoms resemble a cold or flu • The WHO says there is no evidence of more severe illness • Older adults & people with weakened immune systems or chronic conditions face higher risk
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Yuling Chow retweeted
I've had a few people privately concede that they know that repeat COVID infections are harmful but they try not to think about it because it's too overwhelming. I think a decent amount of people understand this but they are stuck.
Has anyone been able to have a real conversation with a 'normal' person about Covid in the past 6.5 years? If so, what was it like?
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Yuling Chow retweeted
#H5N1 ➡️⚠️ U.S. Global Health Strategy Jeopardizes Prevention of Pandemics, Experts Warn - The Trump administration has been negotiating agreements with dozens of individual countries. Public health experts say a global agreement would be far more effective. - ➡️ Country by country, the Trump administration has been negotiating secretive agreements with nations across Africa to provide health aid under strict conditions. ➡️ The agreements, ➡️ structured to benefit the United States, ➡️ are undermining efforts to prepare the world for the next pandemic, putting even Americans at risk, public health experts warn. - In one striking example, under an agreement signed in February that was never made public, ➡️ the United States is set to stop funding health care workers in the Democratic Republic of Congo by the end of the year. Congo has been struggling to contain an Ebola outbreak that has topped 10,000 cases and has spread to two other regions of Africa. - The plan, a copy of which was obtained by The New York Times, provides Congo with $900 million over the next five years, and was signed before the Ebola outbreak was detected. - Still, several public health experts said it was an example of ➡️ the Trump administration’s focus on near-term benefits for the United States over the long-term partnerships needed to weather international crises. - “They have shown incredibly poor foresight proposing further cuts right where workers are needed to fight infectious threats that we all know are coming,” said Peter Maybarduk, the director of access to medicines for the advocacy group Public Citizen. - In response to questions from The New York Times, the State Department said it would work with Congolese officials to ensure they can pay government health workers, but did not say whether it would grant an extension on the Dec. 31 deadline. - ➡️ The administration has signed ➡️ 36 such agreements so far, but ➡️ has not released them publicly. Some agreements, including most recently for Botswana, Cameroon, Eswatini, Ethiopia, Congo and Lesotho, were obtained by Public Citizen through a freedom of information request and made available to The Times. - The State Department has said it ➡️ intends to eventually sign agreements with about 70 countries across the developing world. - ➡️ “One deal at a time risks building 50 slow systems instead of one fast one,” said Dr. Raj Panjabi, who served as the White House’s senior director for global health security and biodefense during the Biden administration. ➡️ “The only way to see that new biological threat fast is a global system where every country is expected to share, and where the U.S. is at the table helping write those rules.” - The next grave health threat could come from a country that has not signed a deal with the United States, he said, or it could be an accidental or deliberate release, perhaps of a pathogen engineered to be more deadly. - The State Department said partnerships with individual countries and regions deliver faster results, and are more accountable, than multilateral agreements. - Dr. Panjabi helped write ➡️ the newest version of the International Health Regulations, ➡️ a legally binding set of rules for countries to detect and disclose outbreaks that could breach borders. ➡️ Member nations of the World Health Organization began following those rules last year. (The rules have since prompted disclosure of the hantavirus outbreak in May and the accidental death of a lab worker in Serbia last month.) - ➡️ But the Trump administration, which ➡️ withdrew the United States from the W.H.O. in January 2025, ➡️ rejected the regulations, inaccurately saying they “would give the W.H.O. the ability to order global lockdowns, travel restrictions, or any other measures it sees fit” during a public health emergency. - ➡️ The United States, along with Israel and Argentina, ➡️ also rejected an agreement last month by member countries of the United Nations ➡️ that pledged collaboration and solidarity in responding to pandemics. - ➡️ “The United States just seems really determined to increase our vulnerabilities by sitting out of the most important conversations,” said Jennifer Nuzzo, a co-developer of the Global Health Security Index, which assesses pandemic preparedness in countries. - Since the Covid-19 pandemic, in which low-income nations lagged richer ones by more than a year in gaining access to vaccines, members of the W.H.O. have been ➡️ trying to hammer out a global treaty that would allow for faster, more equitable access to diagnostic tests, vaccines and treatments the next time. They have until May to finalize the terms. . - But the path to consensus has been rocky. In negotiations, including this week in Geneva, ➡️ low-income nations, including a coalition of African countries, are holding out for guarantees of early and affordable access to medical tools in return for sharing information. ➡️ Higher-income nations are trying to shield intellectual property rights. - ➡️ The United States was involved in the global discussions until President Trump withdrew the nation from the W.H.O. on his first day back in the White House. The administration also cut much of the foreign aid the country disbursed to low-income nations, instead pursuing bilateral deals with countries as part of its “America First Global Health Strategy.” - ➡️ At least 11 of the new agreements, including the one with Congo, include ➡️ requirements to share information from outbreaks in exchange for foreign aid. - ➡️ They require countries to share specimens and related data from an outbreak within five days of receiving a request from the United States. Under the terms, the United States then can share that information with other entities — pharmaceutical companies, for example — that can develop tests and medical countermeasures. - But ➡️ the agreements do not guarantee early or equitable access to the new tests, treatments or other tools that might result. Many give the United States direct access to national health databases, but without privacy protections or oversight from civil society organizations. - The agreements instead say the United States would “prioritize” providing the country with medical tools “behind the U.S. government’s domestic need” and at costs “equal to or below those paid by” the United States. - By contrast, ➡️ the global agreement, once finalized, would provide affordable medical tools to all low-income nations, not just the one that provides information. - Some experts worried that by setting up a parallel process, the American agreements would undermine the already contentious global negotiations. - “The bilateral approach will weaken the effort we are doing to bring the continent together,” said Dr. Jean Kaseya, director general of the Africa Centers for Disease Control and Prevention. - Dr. Kaseya said he advised African ministers to agree to the bilateral deals only if they were satisfied with the terms, and helped some countries like South Sudan negotiate more “respectful” language. But ultimately, he said, “we need to respect sovereignty of our countries.” - A few countries, including Zimbabwe and Namibia, rejected the Trump administration’s demands, saying the terms violated their sovereignty or their laws. The United States withdrew all health aid from Zimbabwe as of Sept. 30, and announced that it would stop funding H.I.V. programs in Namibia after 2027. - Other countries successfully pushed for more favorable terms than their contracts initially proposed. Zambia’s agreement, signed after 10 months of negotiation, is no longer contingent on the Trump administration’s access to Zambia’s minerals, and does not require the country to share information on pathogens for 25 years. - But ➡️ many countries that rely on aid from the United States are not in a position to fight back and forgo aid, Mr. Maybarduk noted. - ➡️ “This is the take-it-or-leave-it deal that the United States has put in front of them in order to restart some of the health funding that was taken away,” he said. “These are the offers you can’t refuse.” - Dr. Samu Bijou Pekwa, chief of staff in Congo’s health ministry, said her country welcomed the agreement with the United States because it would give local officials more control over the funds. American aid was previously carried out by organizations that gave the Congolese government little say over how the money was spent, she said. The organizations were “not even involving us,” she added. - According to the memorandum of understanding with Congo, the United States plans to stop paying health care workers “by the end of 2026, costing $12,025,689,” transitioning that responsibility to the Congolese government. - Dr. Pekwa said Congo and other international partners can take over the payments but the government must ensure the workers exist and then confirm their credentials. That process will take at least six months, she said. - The State Department noted that the United States is the largest donor to the current Ebola response, contributing more than $1.2 billion in health and humanitarian assistance. But experts have said that the loss of logistical and scientific support, once provided by the U.S. Agency for International Development and the U.S. Centers for Disease Control and Prevention, has hindered efforts to contain the outbreak. - Yet some public health experts saw ➡️ reasons for optimism. - Some money for logistics, including transport and testing of patient samples, has come from ➡️ the Pandemic Fund, set up in 2022 to move money quickly in outbreak situations. ➡️ The fund now has a portfolio of $11.5 billion of investment across 128 countries, according to Priya Basu, its director. - She added that new sources, including private companies and countries that have not traditionally been large donors, now seem poised to invest in the fund. - Other experts noted that low- and middle-income countries were learning to collaborate — pooling their resources, expertise and purchasing power — rather than rely on richer nations. - “I think it was just laid bare during Covid that they were on their own,” said Rachel Cohen, a senior adviser for the Drugs for Neglected Diseases Initiative. - ➡️ “There is such an incredible amount of work that’s happening at the national level, at the regional level, at the continental level,” she said. ➡️ “Nobody is waiting around for the U.S. to lead anymore in the same way as before.” By Apoorva Mandavilli nytimes.com/2026/11/06/us/po…
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