@BashiriLab

Microbial Biochemistry and Biotechnology laboratory @AucklandUni @ScienceUoA. #AntimicrobialResistance #MethaneMitigation RT & Like ≠ endorsements

 Auckland, New Zealand
BashiriLab.org
Joined June 2019
  • Tweets436
  • Following545
  • Followers421
8Media
Bashiri Lab retweeted
NZSBMB@nzsbmbSep 28
September 2026 NZSBMB news - mailchi.mp/20f7cf34c3dc/apri…
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Bashiri Lab retweeted
NZSBMB@nzsbmbAug 10
Call for NZSBMB Early Career Awards 2026 - mailchi.mp/9473636c1b50/2026…
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Bashiri Lab retweeted
Neil Stone
@DrNeilStoneJan 17
Don't speak for Iranians Stand with them
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The Biosynthetic Pathway to the Pyrroloiminoquinone Marine Natural Product Ammosamide C | Journal of the American Chemical Society @UofIllinois pubs.acs.org/doi/10.1021/jac…

The Biosynthetic Pathway to the Pyrroloiminoquinone Marine Natural Product Ammosamide C

Abstract. Ammosamide C is a marine natural product containing a highly decorated pyrroloiminoquinone core. Studies on the biosynthetic gene cluster (BGC) t

pubs.acs.org
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Bashiri Lab retweeted
Babak Javid@javid_lab1 Dec 2025
This is a very cool study! A new antibiotic, a new mechanism of action, unlocking new ribosome biology!
WilsonLab@WilsonLab21 Dec 2025
Saskemycin, a potent and selective antimycobacterial agent targeting a unique site on the ribosome - PubMed pubmed.ncbi.nlm.nih.gov/4128…

Saskemycin, a potent and selective antimycobacterial agent targeting a unique site on the ribosome...

Tuberculosis is the deadliest bacterial disease on the planet. The months-long regimen of multiple antibiotics required to treat tuberculosis profoundly affects the microbiome and leads to the...

pubmed.ncbi.nlm.nih.gov
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Bashiri Lab retweeted
Structure@Structure_CP2 Oct 2025
Online now! Allosteric regulation of fungal fatty acid synthesis dlvr.it/TNQwwJ
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Bashiri Lab retweeted
Babak Javid@javid_lab1 Oct 2025
Mycobacterium tuberculosis growth arrest on propionate at acidic pH is suppressed by mutations in phoPR and pyrazinamide treatment biorxiv.org/content/10.1101/…

Mycobacterium tuberculosis growth arrest on propionate at acidic pH is suppressed by mutations in...

Mycobacterium tuberculosis (Mtb) arrests its growth at acidic pH, when grown on specific single carbon sources, including propionate. To understand the basis of the propionate-driven growth arrest at...

biorxiv.org
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Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊 science.org/doi/10.1126/scie…

Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance

Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialization of antibiotics influenced their evolution is limited by a paucity of data...

science.org
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Bashiri Lab retweeted
Sazanov Lab@SazanovL18 Sep 2025
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint! biorxiv.org/content/10.1101/…

Structure of E. coli Twin-arginine translocase (Tat) complex with bound cargo

How the twin-arginine translocase (Tat) system transports fully folded substrate proteins across cellular membranes without disrupting membrane integrity has been a fundamental question in cell...

biorxiv.org
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Bashiri Lab retweeted
CARB-X@CARB_X27 Aug 2025
Attending Queenstown Research Week? Join @CARB_X Chief Scientific Officer Richard Alm, PhD, for his presentation “CARB-X – Accelerating the Development of Novel Products to Tackle AMR.” 📆 Wednesday, September 3 ⏰ 3:30 PM NZST
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Out Now! Deep learning reveals antibiotics in the archaeal proteome bit.ly/4lpohMM #DeepLearning #ArtificialIntelligence #Antibiotics
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Here’s our latest biosynthetic study on swainsonine, nature.com/articles/s41589-0… — a pathway far more complex than expected and packed with enzymes brimming with synthetic potential. Led by our fantastic postdoc, @shaonan_liu, who will soon be starting his own lab in Shenzhen!

Biosynthesis of the α-d-mannosidase inhibitor (−)-Swainsonine

Nature Chemical Biology - Swainsonine is a potent α-d-mannosidase inhibitor, but its biosynthesis remains poorly understood. Here the authors reveal an intriguing epimerization mechanism...

nature.com
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Bashiri Lab retweeted
NZSBMB@nzsbmb8 Aug 2025
August 2025 NZSBMB news - mailchi.mp/6af317d64c8c/apri…
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Bashiri Lab retweeted
CARB-X@CARB_X9 Jul 2025
Join @CARB_X Chief Scientific Officer Richard Alm, PhD at a @MTPConnect_AUS panel discussing innovation in antibiotic R&D, sharing insights on translating AMR research into real-world solutions. 📆 Monday, July 14 ⏰ 12 – 2 PM ACST 🔗 Register now: bit.ly/4kWKp1x
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If you have 30 minutes or so, listen to my recently finished honours student Sarah talking about her project. plantandfood.com/en-nz/artic…

Using AI to help create new plant proteins · Plant & Food Research

Host and senior scientist Dr Jay Jayaraman chats with researcher Sarah Philp-Wright about her work on developing novel plant proteins with the help of AI.

plantandfood.com
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Bashiri Lab retweeted
CARB-X@CARB_X27 Jun 2025
A recent @OpenAccessGov piece by Melissa Gong Mitchell of @AMRAlliance highlighted the urgent need to fix the broken antibiotic R&D pipeline and the role of push incentives like @CARB_X in driving early-stage R&D. 🔗 Read more: bit.ly/43ZWj3e #AMR #StopSuperbugs

AMR: Fixing the broken pipeline for new antibiotics

AMR is projected to cause ten million deaths a year by 2050. So, what are the barriers and solutions behind the creation of new antibiotics?

openaccessgovernment.org
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Bashiri Lab retweeted
Structure@Structure_CP6 May 2025
Introducing Bonnie Murphy, Ville Kaila, Maxie Roessler, Volha Chukhutsina, Alisia Fadini, Sonya Hanson, Filipe Maia, and Kirill Kovalev dlvr.it/TKbj4s
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Thrilled to share our work that reveals unusual biosynthetic machinery for the core architecture of radarin indole-diterpenoids! Check out the incredibly complex cyclisation chemistry by the noncanonical terpene cyclase RadB.😊 @Ferrier_Inst @J_A_C_S pubs.acs.org/doi/10.1021/jac…

Non-Canonical Type II Terpene Cyclases Deliver Rare Terpenoid Architectures

Abstract. Terpene cyclases (TCs) catalyze the generation of complex polycyclic terpenoids through elaborate mechanistic cascades. Very little is known abou

pubs.acs.org
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Non-Canonical Type II Terpene #Cyclases Deliver Rare Terpenoid Architectures by Rose M. McLellan (@Dr_Rose_Gold), Daniel Berry, Rosannah C. Cameron, and Emily J. Parker at @Ferrier_Inst in @J_A_C_S pubs.acs.org/doi/10.1021/jac…
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Our website is now up and running harrislab.co.nz with gratitude to my good friend Chris at mighty.nz
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