Molecular parasitologist leading a lab at the Whitehead Institute for Biomedical Research & MIT. All opinions my own. 🔬🏳️‍🌈🇨🇴

Cambridge, MA
Joined September 2016
Whitehead Institute, a leading biomedical research institute in Cambridge, Massachusetts, is hiring a Genome Technology Core (GTC) Director: wibr.wd1.myworkdayjobs.com/e…
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Sebastian Lourido retweeted
Our parasite genome databases are really gone! The lack of communication and scientific vision ⁦@NIH⁩ is hard to follow. Colossal mistake! ⁦@parasitesrule⁩ ⁦@BSPparasitology⁩ ⁦@theNASciences⁩ ⁦@ScienceMagazine⁩ ⁦@Nature⁩ ⁦@NIAIDNews⁩
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OUT NOW 👉 CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infection🐁 @ChrisJGiuliano @LouridoLab @WhiteheadInst nature.com/articles/s41564-0…
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Researchers in @LouridoLab performed the first genome-wide screen of Toxoplasma gondii in live hosts, revealing genes that are important for infection but previously undetected in cell culture experiments: wi.mit.edu/news/genome-wide-…
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Very excited to share our latest study using cryo-ET to investigate actin filaments in #Apicomplexan parasites. This allowed us to learn where do these filaments originate at the cell tip and how they could be managed down the cell body to power motility! nature.com/articles/s41467-0…
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Toxoplasma gondii causes lifelong, occasionally severe infections in humans. In this news story @LiveScience , I discuss a newly discovered Achilles’ heel in the parasite that may bring scientists closer to developing a cure. livescience.com/health/virus…
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Sebastian Lourido retweeted
How it started for @RockefellerUniv grad student Sally Kornbluth and how it’s going @MIT
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We are hiring! Interested in working for Nature Immunology AND Nature Microbiology? In this new position you can do both, and enjoy developing our coverage of all things related to host-microbe interactions. Apply here: careers.springernature.com/j…
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OUT NOW 👉@LouridoLab Mechanistic insights into how Toxoplasma gondii initiates and commits to chronic differentiation nature.com/articles/s41564-0…
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Sebastian Lourido retweeted
Bossman already said it all: our new work on #toxoplasma chronic-stage differentiation is out, with many thanks due to wonderful colleagues, reviewers, and collaborators! Exceedingly proud of this circular little story 😉
Excited to see this work from @mhlicon now published at @NatureMicrobiol describing a positive feedback loop that regulates #Toxoplasma chronic differentiation. Thank you to all our wonderful coauthors and collaborators! rdcu.be/damHQ
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The parasite toxoplasma gondii usually shifts from an initial, acute infection, to a chronic infection in their human hosts. New work from @LouridoLab uncovers a hierarchy of genes responsible for this transformation: wi.mit.edu/news/positive-fee…
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Sebastian Lourido retweeted
I am thrilled to share my first scientific paper!!! Part I'm most happy and grateful about over the years is the incredible mentorship by @Daugherty_Lab- the most amazing PI an undergrad could ever ask for - and get to do this fun project with @AlexJohnWeitzel and @BriBerryTea!
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Delivery of therapeutic molecules is a major bottleneck for treating a wide range of diseases. Today we describe a new modality for delivering proteins based on an engineered contractile injection system @nature nature.com/articles/s41586-0…
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Why Anti-Trans Laws Are Anti-Science Bills that restrict access to gender-affirming health care ignore research scientificamerican.com/artic…
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Sebastian Lourido retweeted
Excited to see our latest work out in @cellhostmicrobe from a great collaboration with @RossWaller3 and @striepenlab . We obtained the spatial proteome of Cryptosporidium sporozoite and identified novel secretory organelles sciencedirect.com/science/ar…
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Sebastian Lourido retweeted
Ohhh new @LouridoLab preprint is live! Congrats @alexwaichan! Give it a read - you’ll be HOOKed 🪝
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