Manager of Manchester Brain Bank (@MancBrainBank) and researcher in the neuropathology of ageing and neurodegenerative disease. Views are my own.
Joined July 2017
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Our latest collaborative paper suggests long-term intellectual engagement, particularly in academic professions, may offer benefits for cognitive aging.
sciencedirect.com/science/ar…
Andrew Robinson retweeted
Check out our recent paper in @braincomms: C9orf72 dipeptides activate the NLRP3 inflammasome 👇🏻👇🏻👇🏻
With @choyle22, @mere_conjecture, @ComorbidCath, @DNS_UOM, @GJBrainResearch & funded primarily by @AlzSocResearch
Rivers-Auty et al., find that C9orf72 dipeptides cause neuroinflammation in frontotemporal dementia and amyotrophic lateral sclerosis, and highlight the inflammasome as a therapeutic target. Please read the full paper at: edin.ac/3XMzmyV @DrSarahRyan
New paper: Our findings suggest that anti-Aβ therapies are more effective if given before Aβ3pE-42 deposition.
life-science-alliance.org/co…
New publication - Depression in older adults and its associations with sleep and synaptic density.
authors.elsevier.com/c/1jiNB… [kwnsfk27.r.eu-west-1.awstrac…]
Andrew Robinson retweeted
Another interesting clinico-pathological case study using tissue from @MancBrainBank
doi.org/10.1002/mdc3.14125
New paper alert!
Blocking Hippo to boost cognition: science.org/doi/10.1126/scis…
Andrew Robinson retweeted
Don’t miss this week’s issue of #ScienceSignaling!
Experiments in mice suggest that a neuron-supporting factor could be a promising target in depression, scientists discover a new approach that boosts memory in models of Alzheimer’s disease, and more. scim.ag/6N0
Andrew Robinson retweeted
**NEW PAPER ALERT** Delighted for the first work from the Pick’s disease International Consortium (PIC) to be published in Lancet Neurology.. (1/12) thelancet.com/journals/laneu…
Andrew Robinson retweeted
Tissue from Manchester Brain Bank was utilised in this very important study
thelancet.com/journals/laneu…
Self-reported late-life hypertension is associated with a healthy cognitive status and reduced Alzheimer's disease pathology burden:
pubmed.ncbi.nlm.nih.gov/3855…
Great to have been involved in this important work led by @jakobhartmann28 and @GassenNils.
nature.com/articles/s41467-0…
Very proud that my daughter is involved in this great initiative
Our Varsity Academy programme continued today for students from @HathershawC @saddleworth_sch @TheRadclyffe and @OasisLeesbrook ⠀
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We hope you enjoyed your second day of sessions at OSFC!⠀
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#WeAreOSFC⠀
Andrew Robinson retweeted
Our Varsity Academy programme continued today for students from @HathershawC @saddleworth_sch @TheRadclyffe and @OasisLeesbrook ⠀
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We hope you enjoyed your second day of sessions at OSFC!⠀
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#WeAreOSFC⠀
Andrew Robinson retweeted
My first ever research paper is out !! 👩🏼🔬🎉
👉👉pubmed.ncbi.nlm.nih.gov/3832…
A natural product "brazilin" inhibits the NLRP3 inflammasome pathway, a key driver of numerous inflammatory human diseases including those affecting the brain such as stroke and dementia. – at Manchester, England
Andrew Robinson retweeted
Apolipoprotein-E genotyping in formalin-fixed and paraffin-embedded post-mortem brain tissue
#neurodegeneration
onlinelibrary.wiley.com/doi/…
ALT Formalin-fixed paraffin-embedded brain tissue held in tissue banks constitutes a valuable research resource, especially when associated with clinical annotations and longitudinal psychometric testing. Apolipoprotein-E (APOE) genotyping is important to fully characterize this resource. A maximum of three years in paraffin was determined for robust APOE genotyping of FFPE tissue using PCR-RFLP.
Andrew Robinson retweeted
Latest paper from the team at MBB!
Apolipoprotein‐E genotyping in formalin‐fixed and paraffin‐embedded post‐mortem brain tissue onlinelibrary.wiley.com/doi/…
Congratulations to @MinshNeuro on his first 'first author' paper!
Proud to share my first first-name paper! It's been a long time coming. @MancBrainBank
Apolipoprotein‐E genotyping in formalin‐fixed and paraffin‐embedded post‐mortem brain tissue - Minshull - Brain Pathology - Wiley Online Library onlinelibrary.wiley.com/doi/…
Andrew Robinson retweeted
The countdown is on to the Jeff Showcase 2024! We're really looking forward to welcoming everyone this Friday at Hyatt Regency Manchester. All the details, from venue to programme can be found here:
eventbrite.co.uk/e/geoffrey-…
See you there! #Jeffshowcase2024
