Manchester Brain Bank provides human brain tissue samples to #neuroscience researchers worldwide. Part of @FBMH_UoM and sits within @DNS_UOM. Admin is @MBB_Andy
Joined April 2023
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Are you a #neuroscience researcher looking for access to human brain tissue samples to use in your research? Visit sites.manchester.ac.uk/manch… to find out how we can help!
Congratulations to our collaborator, Liam Walker, on being awarded the @NCAresearchNHS Star of the month!
Manchester Brain Bank retweeted
Check out our recent paper in @braincomms: C9orf72 dipeptides activate the NLRP3 inflammasome 👇🏻👇🏻👇🏻
With @choyle22, @mere_conjecture, @ComorbidCath, @DNS_UOM, @GJBrainResearch & funded primarily by @AlzSocResearch
Rivers-Auty et al., find that C9orf72 dipeptides cause neuroinflammation in frontotemporal dementia and amyotrophic lateral sclerosis, and highlight the inflammasome as a therapeutic target. Please read the full paper at: edin.ac/3XMzmyV @DrSarahRyan
PhD opportunity - Investigate the Role of Neurovascular Potassium Channels in Aging and Alzheimer's Disease with @GinnyHawkins4, @MBB_Andy and the rest of the specialised supervisory team!
findaphd.com/phds/project/th…
Manchester Brain Bank retweeted
New paper: Our findings suggest that anti-Aβ therapies are more effective if given before Aβ3pE-42 deposition.
life-science-alliance.org/co…
Manchester Brain Bank retweeted
New publication - Depression in older adults and its associations with sleep and synaptic density.
authors.elsevier.com/c/1jiNB… [kwnsfk27.r.eu-west-1.awstrac…]
Manchester Brain Bank retweeted
Pick's Disease Presenting as Tremulous Parkinsonism with Limited Levodopa Response—A Rare Cause of Corticobasal Syndrome - Bhattacharjee - Movement Disorders Clinical Practice - Wiley Online Library movementdisorders.onlinelibr…
Another interesting clinico-pathological case study using tissue from @MancBrainBank
doi.org/10.1002/mdc3.14125
Manchester Brain Bank retweeted
New paper alert!
Blocking Hippo to boost cognition: science.org/doi/10.1126/scis…
Manchester Brain Bank retweeted
Registration is open for our ‘IHC workshop: Post-mortem human brain tissue’
📆 May 2nd 2024
⏰ 9am CDT · 3pm BST · 4pm CEST
🖥 Via Zoom
Register early to secure your free place:
ptglab.zoom.us/webinar/regis…
@MancBrainBank #ProteintechEvents #Immunohistochemistry #Neuroscience
Manchester Brain Bank retweeted
**NEW PAPER ALERT** Delighted for the first work from the Pick’s disease International Consortium (PIC) to be published in Lancet Neurology.. (1/12) thelancet.com/journals/laneu…
Tissue from Manchester Brain Bank was utilised in this very important study
thelancet.com/journals/laneu…
Manchester Brain Bank retweeted
Self-reported late-life hypertension is associated with a healthy cognitive status and reduced Alzheimer's disease pathology burden:
pubmed.ncbi.nlm.nih.gov/3855…
Manchester Brain Bank retweeted
Great to have been involved in this important work led by @jakobhartmann28 and @GassenNils.
nature.com/articles/s41467-0…
Manchester Brain Bank retweeted
Apolipoprotein-E genotyping in formalin-fixed and paraffin-embedded post-mortem brain tissue
#neurodegeneration
onlinelibrary.wiley.com/doi/…
ALT Formalin-fixed paraffin-embedded brain tissue held in tissue banks constitutes a valuable research resource, especially when associated with clinical annotations and longitudinal psychometric testing. Apolipoprotein-E (APOE) genotyping is important to fully characterize this resource. A maximum of three years in paraffin was determined for robust APOE genotyping of FFPE tissue using PCR-RFLP.
Latest paper from the team at MBB!
Apolipoprotein‐E genotyping in formalin‐fixed and paraffin‐embedded post‐mortem brain tissue onlinelibrary.wiley.com/doi/…
Manchester Brain Bank retweeted
The countdown is on to the Jeff Showcase 2024! We're really looking forward to welcoming everyone this Friday at Hyatt Regency Manchester. All the details, from venue to programme can be found here:
eventbrite.co.uk/e/geoffrey-…
See you there! #Jeffshowcase2024
Manchester Brain Bank retweeted
My buddies @MancBrainBank just reminded me of this nice wee paper showing that extended post mortem delay does not meaningfully impact metrics of tissue quality.
link.springer.com/article/10…
Manchester Brain Bank retweeted
It’s the NIHR Great Northern Research Conference today in Manchester @alishaneuro @stu_art_here & @josiemthomas are manning our exhibition stand. Come and say hello! #GNRC2023
Manchester Brain Bank retweeted
Senior Lecturer Dr Claire Troakes showing Sophia how Alzheimer’s Disease looks under the microscope! #AD #neurotwitter #neuroscience #kclbrainbank – at Camberwell, London