@MiloLabWIS

Ron Milo's lab at the Weizmann Institute of Science

weizmann.ac.il/plants/Milo/home
Joined March 2020
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  • Following71
  • Followers1.4K
77Media
A picture is worth 2 trillion cells The estimated distribution of immune cells in the human body 🎨
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How did I only just discover BioNumbers??? It's "the database of useful biological numbers" — amazing! This is an excellent resource to find interesting things like, "how many bacteria are in the ocean?" to add to an article or talk. Check it out --> bionumbers.hms.harvard.edu/s…
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Day 7 of our #2020InReview in memory of Arren, #arrenwithus: The reconstruction of a bacterial CO2 concentrating mechanism (CMM) in a synthetic-autotrophic E. coli. Great example of portability and investigation of CMMs By @flamholz et al. elifesciences.org/articles/5…
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How does our #planet look in 2020 compared to the early 20th cen.? Today, the mass of #materials like concrete, steel, and #plastics = mass of all #life on our #planet. Learn more: bit.ly/3a6SKOA @MiloLabWIS #environmentalawareness

The Mass of Human-Made Materials Now Equals the Planet’s Biomass

REHOVOT, ISRAEL—December 9, 2020—The mass of all human-produced materials – concrete, steel, plastics, asphalt, etc. – has now grown to equal the mass of all life on the planet, its biomass.

weizmann-usa.org
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Milo Lab @WIS retweeted
Avi Flamholz@flamholz3 Dec 2020
Our paper has reached it's final form, a fancy typeset PDF @eLife elifesciences.org/articles/5…

Functional reconstitution of a bacterial CO2 concentrating mechanism in Escherichia coli

A bacterial CO2 concentrating mechanism enables Escherichia coli to fix CO2 from ambient air into biomass.

elifesciences.org
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Milo Lab @WIS retweeted
Martin Jonikas@JonikasLab4 Dec 2020
Engineering of a CO2 concentrating mechanism into crops is likely to help make more food with fewer resources. A key breakthrough by @flamholz @SavageCatsOnly @MiloLabWIS now published: the first transfer of such a mechanism to a different organism. elifesciences.org/articles/5…
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Did you know that it is possible to recreate a carbon fixation pathway in a heterotrophic bug by recruiting only endogenous enzymes? Check out this just-published great work of ours @AriSatanowski @BDronsella and @SteffenNLindner! GED-IT-ON! nature.com/articles/s41467-0…

Awakening a latent carbon fixation cycle in Escherichia coli

Nature Communications - Current efforts to establish synthetic carbon fixation in model heterotrophs rely on expression of heterologous enzymes. Here, the authors explore the presence and activity...

nature.com
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Number 5: “Engineering Microbes to Produce Fuel, Commodities, and Food from CO₂” from @MiloLabWIS and coworkers from @WeizmannScience. cell.com/cell-reports-physic…
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Milo Lab @WIS retweeted
Avi Flamholz@flamholz21 Oct 2020
It's alive!!! elifesciences.org/articles/5…

Functional reconstitution of a bacterial CO2 concentrating mechanism in Escherichia coli

A bacterial CO2 concentrating mechanism enables Escherichia coli to fix CO2 from ambient air into biomass.

elifesciences.org
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Check out our new perspective on 'Engineering Microbes to Produce Fuel, Commodities, and Food from CO2' at @CellRepPhysSci Great team effort with @yinonbaron, Roee Ben-Nissan at the @MiloLabWIS cell.com/cell-reports-physic…

Engineering Microbes to Produce Fuel, Commodities, and Food from CO2

Combining renewable-energy-harvesting systems with synthetic-CO2-using microorganisms is a promising avenue for the sustainable capture and conversion of this greenhouse gas into useful products,...

cell.com
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Engineering Microbes to Produce Fuel, Commodities, and Food from CO2 by Ron Milo, Shmuel Gleizer and team @MiloLabWIS @WeizmannScience cell.com/cell-reports-physic…

Engineering Microbes to Produce Fuel, Commodities, and Food from CO2

Combining renewable-energy-harvesting systems with synthetic-CO2-using microorganisms is a promising avenue for the sustainable capture and conversion of this greenhouse gas into useful products,...

cell.com
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Milo Lab @WIS retweeted
Barkai Lab@BarkaiLab23 Sep 2020
We are deeply sorry for the loss of Arren Bar-Even. Arren did his masters as a joint student in Barkai and @TPilpel labs, and his PhD with @MiloLabWIS. We was a great scientist and a fascinating person. We send our condolences to his family, friends and colleagues.
Bar-Even Lab@WeTheBarEvenLab23 Sep 2020
Our lab has faced the greatest loss imaginable. To us Arren was a mentor, a supervisor, a friend and the head of a family. We are shocked and speechless. Our thoughts are with everyone who got to know this unique genius. He will be sorely missed.
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Issue 18 on the cover: fastest RUBISCO by @MiloLabWIS Features on LRRK2 & endomembrane repair, Timeless G4 recognition, & SIRT7 in skin stem cells Also: structure & mechanism of SARS-CoV2 ubiquitin/ISG15-cleaving protease PLpro embopress.org/toc/14602075/2…
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Milo Lab @WIS retweeted
Dan Davidi@dan_davidi15 Sep 2020
Our work on finding the fastest rubisco in nature is featured today on @embojournal cover! Beautiful illustration by @skrahl who made enzyme kinetics look appealing...
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Milo Lab @WIS retweeted
David Heckmann@d_heckmann2 Sep 2020
Very happy to have more work from my time at @ucsd_sbrg out. We estimated maximal in vivo catalytic rates in growth-optimized knock out strains and show that max rates are robust and consistent. Building on fantastic work by @dan_davidi and @MiloLabWIS. pnas.org/content/early/2020/…
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transcriptional- and posttranscriptional control of gene expression in scale. All structures from David Goodsell & RCSBPDB @buildmodels
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Milo Lab @WIS retweeted
Zohar Meir@Zohar__Meir29 Jun 2020
Our work on epigenetic memory at single cell resolution is finally (!) out nature.com/articles/s41588-0… 👏👏 @ZMukamel @aviezer_l @realchimpsky from Amos Tanay group @WeizmannScience @NatureGenet. (1/14)
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The fastest #RUBISCO in nature - identified by @MiloLabWIS @dan_davidi @ShamshoumMelina Z. Guo et al @WeizmannScience using systematical mining of genomics and #metagenomics data as alternative to #syntheticbiology embopress.org/doi/10.15252/e…
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My pride, our new paper at @MiloLabWIS discovering fastest Rubisco from nature! Sixfold faster than plant rubiscos by screening >100 variants @dan_davidi @omc111 @yinonbaron embopress.org/doi/full/10.15…
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Milo Lab @WIS retweeted
Dan Davidi@dan_davidi5 Jun 2020
Plants fix CO2 to biomass. At the core of this process, there is one particularly slow enzyme - rubisco. For decades scientists have tried to improve it with no success. At @MiloLabWIS we asked if #evolution already gave rise to fast variants... embopress.org/doi/full/10.15…

Highly active rubiscos discovered by systematic interrogation of natural sequence diversity

The EMBO Journal - CO2 is converted into biomass almost solely by the enzyme rubisco. The poor carboxylation properties of plant rubiscos have led to efforts that made it the most kinetically...

link.springer.com
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