St Louis, MO
Joined June 2013
- Tweets65
- Following86
- Followers85
- Likes140
Peter Borchian Lin retweeted
We show that cerebellar microglia age differently from microglia in other brain regions, revealing unique molecular and spatial adaptations.
Amazing teamwork with @HenzeDoug!
Huge thanks to the @wysscoray & @StephenQuake labs and @BrainResilience!
cell.com/cell-reports/fullte…
Peter Borchian Lin retweeted
(Nov/11) Tuesday
We are thrilled to invite you to Workshop 5: Fall Intensive – General Application Workshop, co-hosted by @Stanford_AAP & @NextBioLeader !
🧠 Q&A • Peer Review • Application Feedback
💡 Also explore our new series:
🔗 NextBioLeader: sites.google.com/view/nextbi…
Peter Borchian Lin retweeted
🚀 Calling our 🎓Next BioLeader!
Join our PhD Application Workshop!
🗓️ Fri, 6/6, 4–6pm
🎤 Speakers:
🧠 Dr. @RongxinFang – fanglabstanford.org
Alena Smith & Margarita Artiukhova – LSRP ➡️ PhD!
🔗 RSVP: forms.gle/VZB71ZvxUrnTsSy9A
#NextBioLeader #PhDApps #STEMMentorship #Stanford
Peter Borchian Lin retweeted
Another @wysscoray & @StephenQuake labs collaboration! 🔬 With @HenzeDoug, we identify a subtype of disease-associated microglia with a ramified morphology, challenging conventional assumptions between cellular morphology and microglial states.🧠#Microglia biorxiv.org/content/10.1101/…
Peter Borchian Lin retweeted
Our new study! 🚀 With @HenzeDoug, we uncover region-specific adaptations in cerebellar microglia and provide detailed molecular and spatial data on age-related glial changes in the cerebellum. 🧠 #Microglia
A @wysscoray & @StephenQuake labs collaboration! biorxiv.org/content/10.1101/…
Peter Borchian Lin retweeted
Check out the latest from @Model_ad_alz alzforum.org/news/research-n…
Peter Borchian Lin retweeted
Excited to share our work published in @ImmunityCP! We validated the human genetic findings that loss- and gain-of-function PLCG2 variants have opposite effects on transcriptional mechanisms, altering microglial phenotypes and AD pathology in mouse models. cell.com/immunity/fulltext/S…
Peter Borchian Lin retweeted
Very excited to share that my first first-author paper with @jungsukim77 was published this morning in @JExpMed 😄
Thank you to all the lab members, collaborators, and everyone who made this possible!
Acri (@domjacri), @jungsukim77 et al. report transcriptomic responses to tau & elevated tau seeding activity in wild-derived mice relative to C57BL/6J. This paper creates a rich resource by combining genetics, tau biosensor assays, & transcriptomics. bit.ly/47Ky7mA
Peter Borchian Lin retweeted
Amyloid pathology dysregulates proteostasis by reducing ELP3 expression and tRNA modification levels! Congratulations to the team @SoaresRna @MarisaP49702171!
1/2 And here it is, our most recent publication showing the impact of tRNA modifications in Alzheimer's Disease! Congratulations @MarisaP49702171 for your final PhD paper! sciencedirect.com/science/ar…
Peter Borchian Lin retweeted
I'm looking for a research professional 1 to work with me on microglia, lipidome, or aging clock. Please feel free to contact me! So many opportunities and projects in the Wyss-Coray lab (web.stanford.edu/group/twcla…)!
Link for this job:
careersearch.stanford.edu/jo…
Peter Borchian Lin retweeted
Excited to share our new study about how TREM2 splice isoforms can contribute to a pool of heterogenous sTREM2 and affect synaptic plasticity. @Mad4Microglia @Andy_P_Tsai @icoronelm @LasagnaLab @BradyAtwood @pbmartinc @KwangsikN @btlamb genomemedicine.biomedcentral…
Peter Borchian Lin retweeted
Want to hear about Tau seeding, Genetic Diversity, and Transcriptomic signatures??
@allftd @alzassociation @RCFNeuro
Check out our bioRxiv below⬇️⬇️⬇️
Network analysis reveals strain-dependent response to misfolded tau aggregates biorxiv.org/cgi/content/shor… #biorxiv_neursci
Peter Borchian Lin retweeted
ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy science.org/doi/10.1126/scie… A delayed tweet. Congrats to Dong-oh Seo and all our great collaborators in this interesting and comprehensive work.
Peter Borchian Lin retweeted
Indiana University School of Medicine researchers @adrianoblak @Peter_BC_Lin are studying how the reduction of a gene variant found in the brain’s immune cells could diminish the risk of late-onset Alzheimer’s disease.
neurosciencenews.com/alzheim…
Peter Borchian Lin retweeted
Congratulations to the team led by @adrianoblak! As a follow up of our 2021 paper (sciencedirect.com/science/ar…), @Peter_BC_Lin found that INPP5D haplodeficiency perturbs microglial signaling pathways, regulating phagocytosis and amyloid plaques clearance (alz-journals.onlinelibrary.w…).
Peter Borchian Lin retweeted
Congrats to @adrianoblak and the @NeurosciStark crew on the fantastic study. INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease alz-journals.onlinelibrary.w…
Peter Borchian Lin retweeted
Check out our newest work by @Peter_BC_Lin in Alz and Dementia @alzassociation where we found reduced Inpp5d attenuates disease pathogenesis. @Andy_P_Tsai @Mad4Microglia @miguelcmoutinho @btlamb alz-journals.onlinelibrary.w…
Peter Borchian Lin retweeted
Excellent work Adrian and everyone! Not only finding keys in biology and pathology of ADRD, but also identifying key avenues for potential pharmacological approaches…clearly something special in INPP5D/SHIP1 - kind of how things go @NeurosciStark @Treat_ad_alz @Model_ad_alz
Peter Borchian Lin retweeted
The Gate lab is proud to share our first manuscript, led by the incredibly talented @PiehlNatalie and @LynnOlst. In this manuscript, we discovered CSF immune system changes that occur with healthy brain aging and cognitive impairment. 1/10 cell.com/cell/fulltext/S0092…
Peter Borchian Lin retweeted
Do you have PLCG2 variants? Which one? The one confers increased AD risk or the one protects your brain and extends lifespan? We found that PLCG2 variants can orchestrate microglial responses in AD by distinct programs that can be therapeutically targeted! biorxiv.org/content/10.1101/…
