Gastro Specialist Trainee | IBD researcher
Exeter, Bristol
Joined December 2018
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Simeng Lin retweeted
Not every day you see an odds ratio of 50 (for interleukin-10 autoantibodies and a common HLA allele).
~80% of patients with inflammatory bowel disease (IBD) have this HLA allele
These individuals (~3.5% of IBD) may benefit from B cell depletion (such as achieved via CAR T).
nejm.org/doi/full/10.1056/NE…
nejm.org/doi/full/10.1056/NE…
Simeng Lin retweeted
PANTS - Maximising patient data and samples + fantastic collaboration
Recruitment March 2013- July 2016
PANTS - FACTS
👥 1600+ patients
🩺13900 patient visits
🏥118 NHS Hospitals
👩💻300 NHS research staff
🧪~90000 frozen samples
💩~6000 poo samples
@tariqahmadIBD
Simeng Lin retweeted
Due to some last minute changes with HEE posts we are advertising for a trust registrar. Recent post holders have been OGD trained within 9 months and have had lots of abstracts accepted. Also change to work on the exciting liver project @PHI_Comms
@BSGTrainees
This is indeed a great achievement from @esaunsbury @dan_maggs , from a local audit, to a South West trainee network project @SPRinG__network , to a BSG endorsed national audit @EVOLVE_EOLC @ibdseb !
#BSGLIVE23
Fantastic to see how the EVOLVE national audit has developed from the initial regional project we supported in 2021/2022. A great example of what can be achieved by trainee-led initiatives.
@EVOLVE_EOLC #BSGLIVE23
Simeng Lin retweeted
Calling all budding hepatologists!
Exciting PhD opportunity with the Exeter liver team
✅Fully funded for 3 years
✅Opportunity to continue some clinical work (inc HPB endoscopy) if desired
✅Live in beautiful Devon
Please RT!
DM for more details
jobs.nhs.uk/candidate/jobadv…
Simeng Lin retweeted
New preprint by @SimengLin identifying DNA methylation predictors of anti-TNF treatment in IBD patients. doi.org/10.1101/2023.03.22.2… @uniofexeHLS @gw4_cat @UofE_Research
Pleased to share our preprint highlighting the DNA methylation changes in anti-TNF treated patients from the @PANTSresearch study.
Link to preprint: doi.org/10.1101/2023.03.22.2…
Thanks to all our patients, collaborators and funders.
Pleased to share our preprint highlighting the DNA methylation changes in anti-TNF treated patients from the @PANTSresearch study.
Link to preprint: doi.org/10.1101/2023.03.22.2…
Thanks to all our patients, collaborators and funders.
This work has also been presented at #ECCO23 DOP88, a recording of which can be found on the ECCO'23 Virtual Platform.
ecco-ibd.eu/ecco23.html
Simeng Lin retweeted
Excited to share our joint @ResearchBsg / @NIHRresearch Introduction to Research event for all #Gastro trainees 🕵🏼🧑🏾🔬🧑🏻⚕️🧑🏿💻! 21/4/23 in York. Programme below! Huge variety of speakers/topics + invaluable advice. 8️⃣ weeks to go! Sign up early, limited spaces! bit.ly/3lqWvpL
Simeng Lin retweeted
So we’ve had a string of cancellations for this Saturday night. Literally lost half the restaurant. If anyone wants to eat at Wilson’s this Saturday do get in touch. We have space!
RT
Simeng Lin retweeted
Christmas cruise on the River Exe….great afternoon with the @UniofExeter genetics and epigenetics groups.
Simeng Lin retweeted
Exeter IBD research group having a long overdue night out at @topshambrewery on Exeter Quay
Risk of immunogenicity and rates of drug persistence to second anti-TNF following immunogenicity/treatment failure to first anti-TNF.
Results summarised here:
@nchanchlani1 @exeteribdresea1
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Great project led by @esaunsbury and Dan Maggs!
We’re delighted to launch our trainee-led national audit, focusing on end of life care in patients with advanced chronic liver disease. Keen to get involved? See the below details to sign up! Thanks to @BritSocGastro, @NIHRresearch and @uk_torch for their support #LiverTwitter
Results from the latest @clarityibd paper published in @Gut_BMJ summarised here:
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Simeng Lin retweeted
The key question now is - can we improve vaccine responses in patients treated with antiTNF drugs?
The latest @clarityibd paper "Vaccine escape, increased breakthrough and reinfection in IFX-treated patients with IBD during the Omicron wave of the #COVID19 pandemic" is online via bit.ly/3zC441w @DrNickKennedy, @nchanchlani1, @SimengLin, @JamesGoodhand1, @tariqahmadIBD
Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic @Gut_BMJ
Glad to have been a part of this international collaboration @LouisHSLau @nchanchlani1 @DrNickKennedy @Siew_C_Ng
🔥 in press!
What do we need to know about #IBD and #COVID? 🦠
Glad to share our latest review article published on @Gut_BMJ together with @SimengLin @nchanchlani1 @DrNickKennedy @Siew_C_Ng @CUHKGI @CUHKMedicine 🌏🌟
#GITwitter #MedTwitter #COVID19
gut.bmj.com/content/early/20…
Simeng Lin retweeted
Absolutely delighted to have presented this on behalf of @SPRinG__network and is a testament to the excellent work driven by @esaunsbury, Dan and expert mentoring of @hudsonbe81. We have come a long way in less than a year! Can't wait to work with everyone to improve #EOLC
Congratulations to @sheiybani for best trainee research network project . We look forward to supporting this team to scale up to a national project
@BritSocGastro @BSGTrainees