Gastro Specialist Trainee | IBD researcher
Exeter, Bristol
Joined December 2018
- Tweets61
- Following190
- Followers113
- Likes294
Simeng Lin retweeted
Not every day you see an odds ratio of 50 (for interleukin-10 autoantibodies and a common HLA allele).
~80% of patients with inflammatory bowel disease (IBD) have this HLA allele
These individuals (~3.5% of IBD) may benefit from B cell depletion (such as achieved via CAR T).
nejm.org/doi/full/10.1056/NE…
nejm.org/doi/full/10.1056/NE…
Simeng Lin retweeted
PANTS - Maximising patient data and samples + fantastic collaboration
Recruitment March 2013- July 2016
PANTS - FACTS
👥 1600+ patients
🩺13900 patient visits
🏥118 NHS Hospitals
👩💻300 NHS research staff
🧪~90000 frozen samples
💩~6000 poo samples
@tariqahmadIBD
Simeng Lin retweeted
Due to some last minute changes with HEE posts we are advertising for a trust registrar. Recent post holders have been OGD trained within 9 months and have had lots of abstracts accepted. Also change to work on the exciting liver project @PHI_Comms
@BSGTrainees
Simeng Lin retweeted
Calling all budding hepatologists!
Exciting PhD opportunity with the Exeter liver team
✅Fully funded for 3 years
✅Opportunity to continue some clinical work (inc HPB endoscopy) if desired
✅Live in beautiful Devon
Please RT!
DM for more details
jobs.nhs.uk/candidate/jobadv…
Simeng Lin retweeted
New preprint by @SimengLin identifying DNA methylation predictors of anti-TNF treatment in IBD patients. doi.org/10.1101/2023.03.22.2… @uniofexeHLS @gw4_cat @UofE_Research
Pleased to share our preprint highlighting the DNA methylation changes in anti-TNF treated patients from the @PANTSresearch study.
Link to preprint: doi.org/10.1101/2023.03.22.2…
Thanks to all our patients, collaborators and funders.
Simeng Lin retweeted
Excited to share our joint @ResearchBsg / @NIHRresearch Introduction to Research event for all #Gastro trainees 🕵🏼🧑🏾🔬🧑🏻⚕️🧑🏿💻! 21/4/23 in York. Programme below! Huge variety of speakers/topics + invaluable advice. 8️⃣ weeks to go! Sign up early, limited spaces! bit.ly/3lqWvpL
Simeng Lin retweeted
So we’ve had a string of cancellations for this Saturday night. Literally lost half the restaurant. If anyone wants to eat at Wilson’s this Saturday do get in touch. We have space!
RT
Simeng Lin retweeted
Christmas cruise on the River Exe….great afternoon with the @UniofExeter genetics and epigenetics groups.
Simeng Lin retweeted
Exeter IBD research group having a long overdue night out at @topshambrewery on Exeter Quay
Simeng Lin retweeted
The key question now is - can we improve vaccine responses in patients treated with antiTNF drugs?
The latest @clarityibd paper "Vaccine escape, increased breakthrough and reinfection in IFX-treated patients with IBD during the Omicron wave of the #COVID19 pandemic" is online via bit.ly/3zC441w @DrNickKennedy, @nchanchlani1, @SimengLin, @JamesGoodhand1, @tariqahmadIBD
Simeng Lin retweeted
Absolutely delighted to have presented this on behalf of @SPRinG__network and is a testament to the excellent work driven by @esaunsbury, Dan and expert mentoring of @hudsonbe81. We have come a long way in less than a year! Can't wait to work with everyone to improve #EOLC
Congratulations to @sheiybani for best trainee research network project . We look forward to supporting this team to scale up to a national project
@BritSocGastro @BSGTrainees
Simeng Lin retweeted
A BIG day for CLARITY IBD
1. The latest video has been released
youtu.be/R67WUchmazA
2. Data has been presented at #ECCO2022 👏👏 @SimengLin
3. @clarityibd research teams across the UK have been working hard updating data so we can release the next publication 👏👏🙏🙏
Simeng Lin retweeted
It was great to be able to share our collaborative project with the BASL End of Life Special Interest Group today. Lots of discussion about the complexity of how to introduce palliative care to patients. Should we be incorporating these skills into registrar training? #BASLEOL
@esaunsbury talking through the identification of patients with advanced liver disease and how to reduce variations in practice - excellent early data from the @SPRinG__network #palliativehepatology #BASLEOL
Simeng Lin retweeted
Great to have in person meeting with the epigenetics group for the first time since 2020…..Lots to catch up on and new faces to meet in the flesh. What an amazing set of colleagues! @UofE_Research @ExeterMed
Simeng Lin retweeted
COVID vaccines & anti-TNF drugs in IBD
We have NEW data from @clarityibd
• serological response to SARS-CoV-2 infection
• antibody & T cell responses to 1 & 2 doses of vaccine
• decay of antibodies over time
• need for boosters
Explained here 👉 youtu.be/Ft8eWa_vXfk
Simeng Lin retweeted
Latest Clarity IBD data available now in preprint. Second dose vaccine antibody and T cell responses in patients with IBD treated with infliximab and vedolizimab researchsquare.com/article/r… – at Drewsteignton, England
Simeng Lin retweeted
The latest results from @clarityibd have been published in @Gut_BMJ.
Excellent paper by @clarityibd @tariqahmadIBD @NickPowellLab @DrNickKennedy @JamesGoodhand1 et al on "Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD" available now via ow.ly/6Svt50ExuJv
Simeng Lin retweeted
Listen to the special #GUTPodcast on both @clarityibd papers by the Exeter IBD Team @tariqahmadIBD @DrNickKennedy @ClaireBewshea @JamesGoodhand1 @NickPowellLab via
ow.ly/R7nJ50ExvMA
@charlie_lees @ibdseb @UKGastroDr @DrChrisLamb @RichardPollok @j0nnymac1 @emadelomar
Simeng Lin retweeted
#GUTInTheNews #GUTPressRelease - read the important paper by @clarityibd team @tariqahmadIBD @DrNickKennedy @JamesGoodhand1 @ClaireBewshea "Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab" via ow.ly/dJTz50E2YMc #COVID19 #IBD