Simeng Lin (@SimengLin) header
Simeng Lin (@SimengLin) profile picture

Gastro Specialist Trainee | IBD researcher

Exeter, Bristol
Joined December 2018
Photo by Simeng Lin (@SimengLin)Photo by Simeng Lin (@SimengLin)Photo by Simeng Lin (@SimengLin)
Simeng Lin retweeted
Not every day you see an odds ratio of 50 (for interleukin-10 autoantibodies and a common HLA allele). ~80% of patients with inflammatory bowel disease (IBD) have this HLA allele These individuals (~3.5% of IBD) may benefit from B cell depletion (such as achieved via CAR T). nejm.org/doi/full/10.1056/NE… nejm.org/doi/full/10.1056/NE…
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PANTS - Maximising patient data and samples + fantastic collaboration Recruitment March 2013- July 2016 PANTS - FACTS 👥 1600+ patients 🩺13900 patient visits 🏥118 NHS Hospitals 👩‍💻300 NHS research staff 🧪~90000 frozen samples 💩~6000 poo samples @tariqahmadIBD
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Simeng Lin retweeted
Due to some last minute changes with HEE posts we are advertising for a trust registrar. Recent post holders have been OGD trained within 9 months and have had lots of abstracts accepted. Also change to work on the exciting liver project @PHI_Comms @BSGTrainees
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Replying to @DrNickKennedy
@DrNickKennedy sharing data on the 3-year anti-TNF outcomes from the PANTS study (awarded Best Clinical Science abstract) On behalf of @nchanchlani1 @exeteribdresea1 and with thanks to all the PANTS collaborators and patients.
We are delighted to congratulate Dr Neil Chanchlani on winning the BMJ Open #Gastroenterology best clinical science abstract for oral presentation with Dr Nick Kennedy presenting on his behalf at the #BSGLIVE23 🎉 @BMJ_Open
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This is indeed a great achievement from @esaunsbury @dan_maggs , from a local audit, to a South West trainee network project @SPRinG__network , to a BSG endorsed national audit @EVOLVE_EOLC @ibdseb ! #BSGLIVE23
Fantastic to see how the EVOLVE national audit has developed from the initial regional project we supported in 2021/2022. A great example of what can be achieved by trainee-led initiatives. @EVOLVE_EOLC #BSGLIVE23
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Calling all budding hepatologists! Exciting PhD opportunity with the Exeter liver team ✅Fully funded for 3 years ✅Opportunity to continue some clinical work (inc HPB endoscopy) if desired ✅Live in beautiful Devon Please RT! DM for more details jobs.nhs.uk/candidate/jobadv…
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Replying to @sheiybani
Congratulations Gio! Great achievement with everything else you have going on!
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Thank you @gw4_cat for the support, right from the start to finish (hopefully soon!)
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New preprint by @SimengLin identifying DNA methylation predictors of anti-TNF treatment in IBD patients. doi.org/10.1101/2023.03.22.2… @uniofexeHLS @gw4_cat @UofE_Research
Pleased to share our preprint highlighting the DNA methylation changes in anti-TNF treated patients from the @PANTSresearch study. Link to preprint: doi.org/10.1101/2023.03.22.2… Thanks to all our patients, collaborators and funders.
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This work has also been presented at #ECCO23 DOP88, a recording of which can be found on the ECCO'23 Virtual Platform. ecco-ibd.eu/ecco23.html
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Pleased to share our preprint highlighting the DNA methylation changes in anti-TNF treated patients from the @PANTSresearch study. Link to preprint: doi.org/10.1101/2023.03.22.2… Thanks to all our patients, collaborators and funders.
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Excited to share our joint @ResearchBsg / @NIHRresearch Introduction to Research event for all #Gastro trainees 🕵🏼🧑🏾‍🔬🧑🏻‍⚕️🧑🏿‍💻! 21/4/23 in York. Programme below! Huge variety of speakers/topics + invaluable advice. 8️⃣ weeks to go! Sign up early, limited spaces! bit.ly/3lqWvpL
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So we’ve had a string of cancellations for this Saturday night. Literally lost half the restaurant. If anyone wants to eat at Wilson’s this Saturday do get in touch. We have space! RT
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Christmas cruise on the River Exe….great afternoon with the ⁦@UniofExeter⁩ genetics and epigenetics groups.
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Exeter IBD research group having a long overdue night out at @topshambrewery on Exeter Quay
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Risk of immunogenicity and rates of drug persistence to second anti-TNF following immunogenicity/treatment failure to first anti-TNF. Results summarised here: @nchanchlani1 @exeteribdresea1
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Great project led by @esaunsbury and Dan Maggs!
We’re delighted to launch our trainee-led national audit, focusing on end of life care in patients with advanced chronic liver disease. Keen to get involved? See the below details to sign up! Thanks to @BritSocGastro, @NIHRresearch and @uk_torch for their support #LiverTwitter
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Results from the latest @clarityibd paper published in @Gut_BMJ summarised here:
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