New On Topic: "Viral Persistence & Long Covid. Parallels with HIV/AIDS" now available.

Thanks for taking the time to give specific examples. Some of this relates to patient advocacy rather than research findings. But being helpful to people with Long Covid who have this particular symptom pattern is quite different from demonstrating a finding about Long Covid itself. It also doesn't apply equally to every person with LC, just a subset. Likely a relatively small percentage when all LC effects are taken into consideration. Percentages will always be debateable of course but a lot of sufferers go unnoticed when one group has a lot of funding, recognition and pre-existing orgs with which to communicate. What I'm interested in is the stronger claim I often hear: that Long Covid can draw on decades of ME/CFS research to understand its underlying biology. For that claim, I'd still be interested in five specific biological/pathophysiological discoveries made through ME/CFS research that have subsequently been demonstrated to be relevant to Long Covid; rather than general energy management lessons, overlapping symptoms, or hypotheses that still need to be tested in Long Covid. The CPET, cerebral blood-flow and metabolic findings are interesting, but the question is whether they've actually helped us understand Long Covid specifically, rather than simply providing untested hypotheses for LC. Some of these findings aren't even consistent across LC studies. And finally, I'm not sure why you added the point about "solidarity & mutual support & concern for all". I haven't suggested that people with ME/CFS, or people with any other condition don't deserve support or concern. My question was specifically about the evidence for what ME/CFS research has contributed to our understanding of LC. I think it's perfectly possible to support people with ME/CFS and ask whether Long Covid has distinct biology that deserves SARS-CoV-2-specific research. Those positions aren't contradictory...but I am seeing far more focus on ME type presentations than the more frequent presentations of LC...and from a LC org that was unexpected and seems to lack focus on the wider patient community.