Cesar Bautista Sotelo (@bautistascience) header
Cesar Bautista Sotelo (@bautistascience) profile picture

Cesar Bautista Sotelo

@bautistascience

He/Him. SouthTX➡️MA. @UTRGV alumni. PhD Candidate at @UMassChan. In the @_MikeLodato Lab 🧬🔬. Pres of @DIGGSBS. Helping lead DEI efforts at UMass Chan.

 UMass Chan Medical School
linkedin.com/in/cesar-bautista-sotelo-6504b7107/
Joined December 2018
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  • Followers148
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Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)Photo by Cesar Bautista Sotelo (@bautistascience)
New preprint from @ScotWolfe1's lab. We address two different bottlenecks of #primeediting (solubility of the PE protein & dNTP concentration in the cell) by rationally engineering new prime editor variants. biorxiv.org/content/10.1101/…
Addressing the dNTP bottleneck restricting prime editing activity

Addressing the dNTP bottleneck restricting prime editing activity

Prime editing efficiency is modest in cells that are quiescent or slowly proliferating where intracellular dNTP levels are tightly regulated. MMLV-reverse transcriptase - the prime editor polymerase...

biorxiv.org
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Congratulations Job Dekker of @UMassChan, newly inducted NAS International Member! #NAS160 #NASmember #genetics #molecularbiology
Image from National Academy of Sciences (@theNASciences)
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Congratulations to @TianxiongYu and @ZhipingWeng on a beautiful paper exploring what drives transposon insertion in Drosophila! academic.oup.com/nar/advance…
Epigenetic and chromosomal features drive transposon insertion in Drosophila melanogaster

Epigenetic and chromosomal features drive transposon insertion in Drosophila melanogaster

Abstract. Transposons are mobile genetic elements prevalent in the genomes of most species. The distribution of transposons within a genome reflects the ac

academic.oup.com
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MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
MD/PhD student Tomás Rodríguez

ALT MD/PhD student Tomás Rodríguez

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Cesar Bautista Sotelo retweeted
Sharon B. Cantor (@CantorLab) profile picture
Sharon B. Cantor@CantorLab8 Jul 2022
In case you missed this point, It’s all about the gaps for therapy response!
Molecular Cell (@MolecularCell) profile pictureMolecular Cell@MolecularCell8 Jul 2022
Exploiting replication gaps for cancer therapy dlvr.it/STYbm1
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Gavin Sherlock (@gsherloc) profile picture
Gavin Sherlock@gsherloc24 Jun 2022
Calling on all conference organizers and professional scientific societies - please do not organize conferences in states that restrict women’s rights. I will certainly not attend and I urge other scientists to not attend. Yes, I know there are also good people in these states 1/
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Eric Green (@NHGRI_Director) profile picture
Eric Green@NHGRI_Director2 Jun 2022
The field of genomics requires deep mental flexibility to solve some of biology’s most challenging questions. A diverse, inclusive genomics workforce is critical so that we gain different perspectives and experiences.
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María Maldonado (@mm5200) profile picture
María Maldonado@mm52002 Jun 2022
How we came to use agar for bacterial plates 😱
Image from María Maldonado (@mm5200)
Image from María Maldonado (@mm5200)
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Sarah Cleveland & Judy Huang, diversity and inclusion co-chairs for the Graduate Student Body Council and active participants in @DIGGSBS, are the winners of the second Student Justice, Equity, Diversity, Inclusion (JEDI) Leadership Award. @Sarahb_clev @judyqyhuang @UMassChanGSBS
Image from UMass Chan Diversity & Inclusion Office (@UMassDiversity)
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Lucas (@lucas__restrepo) profile picture
Lucas@lucas__restrepo1 Jun 2022
My first author paper is out in @Dev_Cell !! We suggest an important functional role for gamma secretase in synapse maturation, many thanks to @drosophilosophy and all of @MoscaLab for their incredible efforts! cell.com/developmental-cell/…
Image from Lucas (@lucas__restrepo)
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Yvon Woappi (@DrWoappi) profile picture
Yvon Woappi@DrWoappi16 May 2022
I am distinguishably honored to announce that I will be joining @Columbia University as the Endowed Herbert and Florence Irving Assistant Professor of Physiology & Cellular Biophysics, and Dermatology, affiliated with Biomedical Engineering @ColumbiaBME, this fall.
Image from Yvon Woappi (@DrWoappi)
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Jill Moore (@MooreJillE) profile picture
Jill Moore@MooreJillE2 May 2022
Excited to announce that today is my first day as an Assistant Professor @UMassChan in @UmassMedbioinfo and @RTI_UMassChan. The Moore Lab is officially open! moore-lab.org 1/4
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Peter J Park (@peter_j_park) profile picture
Peter J Park@peter_j_park29 Apr 2022
I'm thrilled to share our MuSiCal (Mutational Signature Calculator) manuscript: biorxiv.org/content/10.1101/… Mutational signature analysis, pioneered by colleagues at Sanger, has become a key tool for interpreting somatic mutations identified in sequencing data. 3 main concepts (1/8):
Accurate and sensitive mutational signature analysis with MuSiCal

Accurate and sensitive mutational signature analysis with MuSiCal

Mutational signature analysis is a recent computational approach for interpreting somatic mutations in the genome. Its application to cancer data has enhanced our understanding of mutational forces...

biorxiv.org
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New dog paper! #tweetorials from first author @morrilleen and me on way as soon as we figure out how to distill 8 years of work into 280 chars. HUGE thanks to 18K+ dogs & owners @UMassChan @broadinstitute @karlssonlab @darwinsarkfnd #ScienceResearch science.org/doi/10.1126/scie…
Image from Elinor Karlsson (elinork.bsky.social) (@eenork)
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This is really cool unexpected mechanism to cause chromothripsis ! nature.com/articles/s41586-0…
Image from KJ Patel CAM-OX traveller (@ketanpatelimmo1)
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Cesar Bautista Sotelo retweeted
Alper Kucukural (@nephantes) profile picture
Alper Kucukural@nephantes27 Apr 2022
Melissa’s Ted talk ted.com/talks/melissa_j_moor…
Melissa J. Moore: How mRNA medicine will change the world

Melissa J. Moore: How mRNA medicine will change the world

The secret behind medicine that uses messenger RNA (or mRNA) is that it "teaches" our bodies how to fight diseases on our own, leading to groundbreaking treatments for COVID-19 and, potentially one...

ted.com
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Cesar Bautista Sotelo retweeted
Bede Portz (@YSPTSPS) profile picture
Bede Portz@YSPTSPS25 Apr 2022
If I’m faculty at NYU, I’m looking at the female trainees in my lab and at my female colleagues and realizing my institute doesn’t care about them, and I’m considering my exit strategy.
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antisense. (@razoralign) profile picture
antisense.@razoralign23 Apr 2022
Pangolin: Predicting RNA splicing from DNA sequence genomebiology.biomedcentral.…
Image from antisense. (@razoralign)
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Speaks highly of the culture at @nyugrossman. Their statement was heard, “We welcome sexual assault at our institution”
News from Science (@NewsfromScience) profile pictureNews from Science
@NewsfromScience25 Apr 2022
Biologist David Sabatini, who has been forced out of or fired from three leading institutions for sexual misconduct, may now be hired by the New York University Grossman School of Medicine. fcld.ly/m23kyhr
NYU may hire biologist pushed out of MIT, Whitehead for sexual misconduct

NYU may hire biologist pushed out of MIT, Whitehead for sexual misconduct

David Sabatini, forced out of three institutions, appears to have support from NYU medical school dean and a New York billionaire philanthropist

science.org
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Cesar Bautista Sotelo retweeted
Michael Miller (@M_B_Miller) profile picture
Michael Miller@M_B_Miller20 Apr 2022
Excited to share our paper “Somatic genomic changes in single Alzheimer’s disease neurons”, published today in @nature! nature.com/articles/s41586-0… [1/19]
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